- Proteomic Identification of Proteins Suggestive of Immune-Mediated Response or Neuronal Degeneration in Serum of Achalasia Patients
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Im SK, Yeo M, Lee KJ
- KMID: 1806638
- Gut Liver.
- 2013 Jul;7(4):411-416.
BACKGROUND/AIMS: The primary pathophysiologic abnormality in achalasia is known to be a loss of inhibitory myenteric ganglion cells, which may result from an immune-mediated response or neuronal degeneration. The aim... -
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- CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation
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Cho B, Cho HM, Kim HJ, Jeong J, Park SK, Hwang EM, Park JY, Kim WR, Kim H, Sun W
- KMID: 2155370
- Exp Mol Med.
- 2014 Jul;46(7):e105.
- doi: 10.1038/emm.2014.36
Mitochondrial functions are essential for the survival and function of neurons. Recently, it has been demonstrated that mitochondrial functions are highly associated with mitochondrial morphology, which is dynamically changed by... -
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- Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling
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Park J, Seo J, Won J, Yeo HG, Ahn YJ, Kim K, Jin YB, Koo BS, Lim KS, Jeong KJ, Kang P, Lee HY, Baek SH, Jeon CY, Hong JJ, Huh JW, Kim YH, Park SJ, Kim SU, Lee DS, Lee SR, Lee Y
- KMID: 2451076
- Exp Neurobiol.
- 2019 Jun;28(3):414-424.
- doi: 10.5607/en.2019.28.3.414
Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is... -
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- Developmental mRNA Expression of cdk5 and its Putative Regulators, p67 and p35, in Rat Brain
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Kim CM, Kim H, Uhm CS, Rhyu IJ, Park SH, Suh YS
- KMID: 2092781
- Korean J Anat.
- 2001 Oct;34(5):517-524.
Cyclin-dependent kinase 5 (cdk5) is essential for brain development and p35 and p67 are the regulatory molecules for cdk5. In this study, we have investigated the expression of cdk5, p35,... -
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- Restoration of Cdk5, TrkB and Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor Proteins after Chronic Methylphenidate Treatment in Spontaneous Hypertensive Rats, a Model for Attention-Deficit Hyperactivity Disorder
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Kim Y, Jeon S, Jeong HJ, Lee SM, Peña ID, Kim HJ, Han DH, Kim BN, Cheong JH
- KMID: 2454726
- Psychiatry Investig.
- 2019 Jul;16(7):558-564.
- doi: 10.30773/pi.2019.04.22
OBJECTIVE: Synaptic vesicle mobilization and neurite outgrowth regulation molecules were examined in modulation of effects of methylphenidate (MPH) in Spontaneous Hypertensive Rats (SHRs), a model for attention-deficit hyperactivity disorder (ADHD). METHODS:... -
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- Myricetin Protects Against High Glucose-Induced β-Cell Apoptosis by Attenuating Endoplasmic Reticulum Stress via Inactivation of Cyclin-Dependent Kinase 5
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Karunakaran U, Elumalai S, Moon JS, Jeon JH, Kim ND, Park KG, Won KC, Leem J, Lee IK
- KMID: 2442772
- Diabetes Metab J.
- 2019 Apr;43(2):192-205.
- doi: 10.4093/dmj.2018.0052
BACKGROUND: Chronic hyperglycemia has deleterious effects on pancreatic β-cell function and turnover. Recent studies support the view that cyclin-dependent kinase 5 (CDK5) plays a role in β-cell failure under hyperglycemic... -
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