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A current perspective on post-micturition dribble in males

Yang DY, Lee WK

Post-micturition dribble (PMD) is the involuntary loss of urine immediately after urination. It is classified as a post-micturition symptom and is more common in males. Traditionally, PMD has been considered...
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Acute Hemodynamic Changes after Single Administration of Udenafil in Pulmonary Arterial Hypertension: a Phase IIa Study

Chang SA, Kim HK, Chang HJ, Kim DK

BACKGROUND AND OBJECTIVES: Udenafil, a new phosphodiesterase-5 inhibitor (PDE5i), has been used to treat erectile dysfunction. Given the proven benefit of PDE5i in pulmonary arterial hypertension (PAH), we evaluated serial...
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Misuse of testosterone replacement therapy in men in infertile couples and its influence on infertility treatment

Song SH, Sung S, Her YS, Oh M, Shin DH, Lee J, Baek J, Lee WS, Kim DS

OBJECTIVE: We investigated the clinical characteristics of men with testosterone replacement therapy (TRT)-induced hypogonadism and its effect on assisted reproductive technology (ART) in infertile couples. METHODS: This study examined the records...
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Oncological and functional outcomes of robot-assisted radical cystectomy in bladder cancer patients in a single tertiary center: Can these be preserved throughout the learning curve?

Tae JH, Pyun JH, Shim JS, Cho S, Kang SG, Ko YH, Cheon J, Lee JG, Kang SH

PURPOSE: To evaluate the overall and segmental oncological and functional outcome of robot-assisted radical cystectomy (RARC) during the learning curve. MATERIALS AND METHODS: From August 2007 to November 2017, a total...
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A Case of Sexual Enhancer Induced Fixed Drug Eruption

Lee SK, Kim DJ, Suh JH, Kim MS, Lee UH

  • KMID: 2436688
  • Korean J Dermatol.
  • 2018 May;56(4):269-272.
Fixed drug eruption is a commonly reported mucocutaneous drug eruption. A 61-year-old male presented to our clinic with a complaint of an itchy round erythematous patch on the left hand...
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Udenafil, a Phosphodiesterase 5 Inhibitor, Reduces Body Weight in High-Fat-Fed Mice

Ryu SY, Choi YJ, Park SY, Kim JY, Kim YD, Kim YW

PURPOSE: High-fat (HF) feeding induces hypothalamic leptin resistance via the activation of toll-like receptor 4 (TLR4). TLR4 deficiency confers resistance to diet-induced obesity. Udenafil, an anti-impotence drug, inhibits TLR4 in...
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Recreational Use of Phosphodiesterase 5 Inhibitors and Its Associated Factors among Undergraduate Male Students in an Ethiopian University: A Cross-Sectional Study

Gebreyohannes EA, Bhagavathula AS, Gebresillassie BM, Tefera YG, Belachew S, Erku DA

PURPOSE: To assess the prevalence of phosphodiesterase 5 (PDE5) inhibitor use and associated factors among University of Gondar undergraduate students. MATERIALS AND METHODS: An institution-based, cross-sectional study, using a survey questionnaire,...
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Evolution of Phosphodiesterase-5 Inhibitors

Moon DG

No abstract available.
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A Meta-Analysis of Long- Versus Short-Acting Phosphodiesterase 5 Inhibitors: Comparing Combination Use With alpha-Blockers and alpha-Blocker Monotherapy for Lower Urinary Tract Symptoms and Erectile Dysfunction

Choi H, Kim HJ, Bae JH, Kim JH, Moon DG, Cheon J, Yeo JK

PURPOSE: Combination therapy with an alpha-1-adrenergic blocker and phosphodiesterase type 5 inhibitors (PDE5Is) has shown improvements in lower urinary tract symptoms (LUTS) with negligible side effects. Nonetheless, decisive advantages in...
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Comparative Efficacy of Tamsulosin Versus Tamsulosin With Tadalafil in Combination With Prednisolone for the Medical Expulsive Therapy of Lower Ureteric Stones: A Randomized Trial

Kumar S, Jayant K, Agrawal S, Singh SK

PURPOSE: To compare the safety and efficacy of tamsulosin and tamsulosin with the phosphodiesterase-5 inhibitor tadalafil in combination with prednisolone as medical expulsive therapies for lower ureteric stones. MATERIALS AND METHODS:...
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Urologists' Perceptions and Practice Patterns in Peyronie's Disease: A Korean Nationwide Survey Including Patient Satisfaction

Ko YH, Moon KH, Lee SW, Kim SW, Yang DY, Moon DG, Chung WS, Oh KJ, Hyun JS, Ryu JK, Park HJ, Park K

PURPOSE: A nationwide survey was conducted of Korean urologists to illustrate physicians' perceptions and real practical patterns regarding Peyronie disease (PD). MATERIALS AND METHODS: A specially designed questionnaire exploring practice characteristics...
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A Case of Patient with Eisenmenger Syndrome Admitted to Intensive Care Unit Due to Septic Shock Complicated with Newlydiagnosed Down Syndrome and Moyamoya Disease

Lee SJ, Kang HW, Huh JW, Kim SW, Cho HW, Ryu YJ, Lee JH, Chang JH

Eisenmenger syndrome is a severe form of pulmonary arterial hypertension related to congenital cardiac defects. Many patients die at a young age from such complications. The treatment of primary pulmonary...
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Effects of Mirodenafil, a Phosphodiesterase-5 Inhibitor, on Female Rat Bladder in a Partial Bladder Outlet Obstruction Model: Physiological and Immunohistochemical Aspects

Kang JY, Kim EK, Kim KM

PURPOSE: We investigated the effects of mirodenafil, a phosphodiesterase-5 inhibitor developed in South Korea, on the female rat bladder in a partial bladder outlet obstruction (BOO) model. MATERIALS AND METHODS: Thirty-six...
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Therapeutic Angiogenesis as a Potential Future Treatment Strategy for Erectile Dysfunction

Ryu JK, Suh JK

  • KMID: 2320881
  • World J Mens Health.
  • 2012 Aug;30(2):93-98.
The cavernous endothelium plays a crucial role in regulating the tone of the underlying smooth muscle and physiologic penile erection. Recently, the link between erectile dysfunction (ED) and cardiovascular disease...
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A Case of Acute Pulmonary Thromboembolism after Taking Tadalafil

Lee J, Kwon JH, Lee CH, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Park YS

  • KMID: 2320198
  • Tuberc Respir Dis.
  • 2012 Oct;73(4):231-233.
Tadalafil is a phosphodiesterase-5 inhibitor (PDE5I), which is widely used to treat erectile dysfunction. Although PDE5Is have excellent safety profiles, and most of the side effects are mild, rare serious...
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Role of Phosphodiesterase Type 5 Inhibitor on Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms

Kim SD, Park JK

There is strong evidence from multiple epidemiological studies that benign prostate hyperplasia (BPH) induced lower urinary tract symptoms (LUTS) are correlated with erectile dysfunction (ED). Although a direct causal relationship...
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Analysis of Prescriptions of Alpha-Blockers and Phosphodiesterase 5 Inhibitors from the Urology Department and Other Departments

Kang DH, Lee JY, Chung JH, Cho HJ, Cho JM, Moon HS, Kim YT, Yoo TK, Choi HY, Park HY, Lee SW

  • KMID: 2232823
  • Int Neurourol J.
  • 2011 Dec;15(4):216-221.
PURPOSE: We analyzed the prescriptions of alpha-blockers and phosphodiesterase 5 inhibitors (PDE5Is) in the urology department as well as in other departments of the general hospital. METHODS: We investigated the frequency...
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Late-Onset Hypogonadism Syndrome and Lower Urinary Tract Symptoms

Shigehara , Namiki M

Androgen replacement therapy (ART) is a widely accepted form of treatment worldwide for aging men with late-onset hypogonadism (LOH) syndrome. Concurrent with the progressive decline in testosterone from middle age,...
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Corporeal Fibrosis and Erectile Dysfunction as Sequelae of Unrepaired Penile Blunt Trauma

Jo DJ, Ryu DS, Yang SJ

  • KMID: 2298761
  • Korean J Androl.
  • 2010 Dec;28(3):226-228.
Penile fracture is an injury caused by the rupture of the tunica albuginea. We report an uncommon case of penile fracture with corporeal fibrosis and erectile dysfunction in a 45-year-old...
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Vardenafil Enhances Oxytocin Expression in the Paraventricular Nucleus without Sexual Stimulation

Shin MS, Ko IG, Sung YH, Kim SE, Kim BK, Kim CJ, Lee SW, Kim DH, Chang JH, Kim KH

  • KMID: 2232770
  • Int Neurourol J.
  • 2010 Dec;14(4):213-219.
PURPOSE: Oxytocin is associated with the ability to form normal social attachments. c-Fos is an immediate early gene whose expression is used as a marker for stimulus-induced changes in neurons....
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