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The Effect of alpha MSH Analogues on Rat Bones

Lim SK, Li SZ, Rhee Y, Chung SS, Jin YJ, Yook JI

Melanocortin is the downstream mediator of leptin signaling and absence of leptin signaling in ob/ob and db/db mice revealed the enhancement of bone formation through the central regulation. While alpha-melanocyte-stimulating...
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Altered Renal Expression of Aquaporin-2 Water Channels in Rats with Experimental Two-Kidney, One Clip Hypertension

Lee JU, Oh YW, Kim SW

The present study was aimed at examining the regulation of aquaporin (AQP)-2 water channels in the kidney in two-kidney, one clip (2K1C) hypertension. Rats were made 2K1C hypertensive for 6...
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An inhibitory compound against the interaction between Galpha(s) and the third intracellular loop region of serotonin receptor subtype 6 (5-HT(6)) disrupts the signaling pathway of 5-HT(6)

Choi YH, Kang H, Lee WK, Kim T, Rhim H, Yu YG

  • KMID: 1047084
  • Exp Mol Med.
  • 2007 Jun;39(3):335-342.
Serotonin receptor subtype 6 (5-HT(6)) is a neurotransmitter receptor, which is involved in various brain functions such as memory and mood. It mediates signaling via the interaction with a stimulatory...
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