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Circulating factors in sera or peripheral blood mononuclear cells in patients with membranous nephropathy or diabetic nephropathy

Ihm CG, Park JK, Hong SP, Lee TW, Cho BS, Kim MJ

In order to investigate the status of some circulating factors in nephrotic syndrome, we examined the secretion of monocyte chemotactic peptide (MCP)-1, tumor necrosis factor (TNF) alpha or fibronectin...
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Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells

Jeon YJ, Kim YS

BACKGROUND/AIMS: Hypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. METHODS: Huh7 cells were...
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Suppression of NF-kappaB activation in normal T cells by supernatant fluid from human renal cell carcinomas

Kim HJ, Park JK, Kim YG

T lymphocytes from patients with renal cell carcinoma (RCC) show reduced immune function and impaired activation of the transcription factor, NF-kappaB. We determined the mechanism of NF-kappaB suppression in T...
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Hypoxia Induces Connective Tissue Growth Factor mRNA Expression

Lee YK, Kim EJ, Lee JE, Noh JW, Kim YG

Connective tissue growth factor (CTGF) is known to be a profibrotic growth factor, which mediate the fibrotic effect of transforming growth factor-beta(TGF-beta) and to stimulate cell proliferation and matrix production....
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