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A meningococcal B vaccine induces cross-protection against gonorrhea

Azze RF

PURPOSE: Neisseria meningitidis and Neisseria gonorrhoeae share between 80% and 90% of their genetic sequence. Meningococcal serogroup B vaccines based on outer membrane vesicles—such as VA-MENGOC-BC—could cross-protect against gonorrhea. The...
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Evaluation of the effect of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms

Puente R, Illnait J, Mas R, Carbajal D, Mendoza S, Fernandez , Mesa M, Gamez R, Reyes P

BACKGROUND/AIMS: Nonsteroidal anti-inflammatory drugs relieve osteoarthritis (OA) symptoms but cause adverse effects. D-002, a mixture of beeswax alcohols, is effective against experimental OA. A pilot study found that D-002 (50...
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Effects of D-003 (10 mg/day) on Bone Mineral Density of the Lumbar Spine and Femoral Neck in Postmenopausal Women: A Randomized, Double-Blinded Study

Ceballos A, Castano G, Mendoza S, Gonzalez J, Mas R, Fernandez , Illnait J, Mesa M, Gamez R, Fernandez , Telles R, Marrero D, Eng MG, Ruiz D, Jardines Y

BACKGROUND/AIMS: Increased osteoclast activity is a pivotal finding in osteoporosis. This increase is mediated via the mevalonate-to-cholesterol pathway, which is involved in producing the intermediates required for osteoclast activity. D-003,...
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Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease

Illnait J, Rodriguez , Mendoza S, Fernandez , Mas R, Miranda M, Pinera J, Fernandez , Mesa M, Fernandez , Carbajal D, Gamez R

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and...
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