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Effect of renin-angiotensin-system blockers on contrast-medium-induced acute kidney injury after coronary angiography

Goo JJ, Kim JJ, Kang JH, Kim KN, Byun KS, Kim MK, Kim TI

BACKGROUND/AIMS: With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI...
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Preventive Effect of Pretreatment with Intravenous Nicorandil on Contrast-Induced Nephropathy in Patients with Renal Dysfunction Undergoing Coronary Angiography (PRINCIPLE Study)

Ko YG, Lee BK, Kang WC, Moon JY, Cho YH, Choi SH, Hong MK, Jang Y, Kim JY, Min PK, Kwon HM, PRINCIPLE Investigators

PURPOSE: To investigate the effect of pretreatment with intravenous nicorandil on the incidence of contrast-induced nephropathy (CIN) in patients with renal dysfunction undergoing coronary angiography. MATERIALS AND METHODS: This randomized controlled...
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