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Favorable long-term survival using consolidation chemotherapy without allogeneic hematopoietic cell transplantation for acute myeloid leukemia with wild-type NPM1 without FLT3-ITD

Baek DW, Lee JM, Kim JH, Cho HJ, Ham JY, Suh JS, Sohn SK, Moon JH

BACKGROUND: The role of allogeneic hematopoietic cell transplantation (allo-HCT) compared with consolidation chemotherapy alone in intermediate-risk acute myeloid leukemia (AML) patients with wild-type nucleophosmin/negative or a low level of Fms...
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Organ Preservation Strategies After Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

Yoo RN, Kim HJ

Standard use of neoadjuvant chemoradiotherapy, total mesorectal excision, and postoperative adjuvant chemotherapy in locally advanced rectal cancer has tremendously improved oncologic outcomes over the past several decades. However, these improvements...
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Is Second Look Laparoscopy for Diagnosing Remaining Ovarian Cancer Appropriate Further Treatment?

Inamdar R, Cho A, Yoo HK, Moon HS

OBJECTIVES: The aim of our study is to compare the findings of investigative modalities and second look laparoscopy in ovarian cancer and establish the safety and accuracy of second look...
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Isolated pulmonary Langerhans cell histiocytosis in a 10-month-old infant

Jang H, Kim YH, Kim KW, Sohn MH, Lyu CJ

Langerhans cell histiocytosis (LCH) is characterized by clonal proliferation and accumulation of abnormal dendritic (Langerhans) cells in various organs. Pulmonary involvement, although rare in children, has been reported in 20%–50%...
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Preoperative short course radiotherapy with concurrent and consolidation chemotherapies followed by delayed surgery in locally advanced rectal cancer: preliminary results

Aghili M, Sotoudeh S, Ghalehtaki R, Babaei M, Farazmand , Fazeli MS, Keshvari A, Haddad P, Farhan F

PURPOSE: This study aimed to assess complications and outcomes of a new approach, that is, combining short course radiotherapy (SRT), concurrent and consolidative chemotherapies, and delayed surgery. MATERIALS AND METHODS: In...
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The outcomes of intensified 5-fluorouracil plus leucovorin chemotherapy for preoperative chemoradiation in rectal cancers

Ha N, Hong KD, Ji WB, Kim JS, Um JW

PURPOSE: The clinical benefit of intensified neoadjuvant chemoradiotherapy (CRT) in rectal cancer has not been proved. We investigated clinical outcomes of intensified 5-fluorouracil plus leucovorin (5-FU/LV) chemotherapy. METHODS: We retrospectively analyzed...
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Chemoradiotherapy followed by consolidation chemotherapy involving paclitaxel and carboplatin and in FIGO stage IIIB/IVA cervical cancer patients

Mabuchi S, Isohashi F, Okazawa M, Kitada F, Maruoka S, Ogawa K, Kimura T

OBJECTIVE: To evaluate the efficacy and toxicity of paclitaxel plus carboplatin (TC)-based concurrent chemoradiotherapy (CCRT) followed by consolidation chemotherapy in the International Federation of Gynecology and Obstetrics (FIGO) stage IIIB/IVA...
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Bullae-Forming Pulmonary Metastasis from Choriocarcinoma Presenting as Pneumothorax

Hyun K, Jeon HW, Kim KS, Choi KB, Park JK, Park HJ, Wang YP

Gestational trophoblastic disease (GTD) is a condition of uncertain etiology, choriocarcioma, or placental-site hydatidiform moles, invasive moles, choriocarcinoma, and placental-site trophoblastic tumors. It arises from the abnormal proliferation of trophoblastic...
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Inadvertent Transmission of a Donor's Constitutional Chromosome Abnormality after Hematopoietic Stem Cell Transplantation

Yun J, Jo HH, Jeon BR, Lee YK, Kim CK, Park SK, Hong DS

A pre-transplant screening work-up of donors for allogeneic hematopoietic stem cell transplantation (HSCT) is essential. Inadvertent transmission of malignancy from donors with subclinical diseases to recipients has been reported recently...
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Long-Term Survival after T-cell Lymphoblastic Lymphoma Treated with One Cycle of Hyper-CVAD Regimen

Ryu IH, Cho IS, Ryu AJ, Kim MG, Jeon JW, Kim JS, Lee JJ, Choi JW, Kang DW

T-lymphoblastic lymphoma (T-LBL) is a rare form of aggressive non-Hodgkin's lymphoma. The standard approach for management of T-LBL involves intensive multiagent chemotherapy regimens for induction and consolidation phases with central...
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Cytomegalovirus appendicitis with concurrent bacteremia after chemotherapy for acute leukemia

Cho MJ, Lee J, Hu JY, Lee JW, Cho SY, Lee DG, Lee S

No abstract available.
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Gynecologic complication of chronic graft-versus-host disease: Vaginal obstruction

Park J, Kim TH, Lee HH, Chung SH, Lee D

  • KMID: 2313963
  • Obstet Gynecol Sci.
  • 2013 Jul;56(4):277-280.
Allogenic peripheral blood stem cell transplantation (Allo-PBSCT) is being used to treat hematological malignancies with increasing frequency. Graft-versus-host disease (GvHD) is a complex complication of PBSCT. A 43-year-old woman came...
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Effect of early chemoradiotherapy in patients with limited stage small cell lung cancer

Ha IB, Jeong BK, Jeong H, Choi HS, Chai GY, Kang MH, Kim HG, Lee GW, Na JB, Kang KM

PURPOSE: We evaluated the effect of early chemoradiotherapy on the treatment of patients with limited stage small cell lung cancer (LS-SCLC). MATERIALS AND METHODS: Between January 2006 and December 2011, thirty-one...
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Phase II Study of Consolidation Chemotherapy after Adjuvant or Primary Concurrent Chemoradiation Using Paclitaxel and Carboplatin to Treat High-Risk Early-Stage or Locally Advanced Cervical Cancer

Kim HS, Kim MK, Kim HJ, Han SS, Kim JW

  • KMID: 2167594
  • Cancer Res Treat.
  • 2012 Jun;44(2):97-103.
PURPOSE: This study investigated the efficacy and toxicity associated with consolidation chemotherapy using paclitaxel and carboplatin after concurrent chemoradiation (CCR) in cervical cancer patients. MATERIALS AND METHODS: From a total of...
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A Case of Disseminated Candidiasis and Subsequent Breakthrough Pulmonary Mucormycosis after Consolidation Chemotherapy for Acute Myeloid Leukemia

Kim YM, Kong S, Kim SJ, Kim H, Lee KE, Lee SJ, Lee HN, Cho MJ, Lee JW, Lee DG

Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in patients with acute leukemia who are receiving chemotherapy. Primary prophylaxis with antifungal agents has become the standard...
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Comparison of concurrent chemoradiation therapy with weekly cisplatin versus monthly fluorouracil plus cisplatin in FIGO stage IIB-IVA cervical cancer

Kong TW, Chang SJ, Paek J, Yoo SC, Yoon JH, Chang KH, Chun M, Ryu HS

OBJECTIVE: Concurrent chemoradiation therapy (CCRT) is the standard treatment for locally advanced cervical cancer. Although the optimal chemotherapeutic regimen is not yet defined, previous randomized trials have demonstrated that 5-fluorouracil...
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Clinical Responses and Prognostic Indicators of Concurrent Chemoradiation for Non-small Cell Lung Cancer

Lee DS, Kim YS, Kang JH, Lee SN, Kim YK, Ahn MI, Han DH, Yoo IR, Wang YP, Park JG, Yoon SC, Jang HS, Choi BO

  • KMID: 1804673
  • Cancer Res Treat.
  • 2011 Mar;43(1):32-41.
PURPOSE: To evaluate treatment outcomes and prognostic factors in non-small cell lung cancer (NSCLC) patients treated with concurrent chemoradiation. MATERIALS AND METHODS: From January 2005 to June 2009, 51 patients were...
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Improved outcome in childhood ALL with intensive consolidation and hematopoietic stem cell transplant

Park JA, Ghim T, Bae KW, Koh KN, Im HJ, Seo JJ

BACKGROUND: Despite advances in chemotherapy, the prognosis of relapsed acute lymphoblastic leukemia (ALL) remains poor. Few studies on relapsed ALL have reported the importance of intensive consolidation followed with or...
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Allogeneic Hematopoietic Stem Cell Transplantation Following Imatinib Plus Idarubicin and High-dose Cytarabine in Children with Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

An SA, Kim MH, Lee JW, Lee DH, Jang PS, Chung NG, Cho B, Jeong DC, Kim HK

  • KMID: 2168944
  • Clin Pediatr Hematol Oncol.
  • 2010 Oct;17(2):163-173.
PURPOSE: To investigate the feasibility of imatinib-combined chemotherapy prior to allogeneic hematopoietic stem cell transplantation (HSCT) in childhood Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL), we treated five children with...
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Concurrent Chemoradiotherapy in Elderly Patients with Locally Advanced Esophageal Carcinoma

Jung BK, Kang KM, Lee GW, Kang JH, Kim HG, Lee WS, Chai GY

PURPOSE: The effect of concurrent chemoradiotherapy was analyzed in elderly patients when used in the treatment of locally advanced esophageal cancer. MATERIALS AND METHODS: The retrospective analysis included 28 elderly patients...
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