- Immunoglobulin Gene Repertoire In Rheumatoid Synovium As A Model For Autoimmune Disease
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Lee SK, Song JH
- KMID: 2334737
- J Korean Rheum Assoc.
- 1994 Jul;1(2):200-212.
OBJECTIVE: To gain insights into structural characteristics of immunoglobulin kappa chain repertoire expressed in the inflammed synovium of rheumatoid arthritis (RA), we analyzed V kappa transcirpts expressed in the synovium... -
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- Clonality of Lymphocytic Interstitial Pneumonia in Common Variable Immunodeficiency
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Kang KW, Lee YS, Kim HM, Yae BI, Kim TH, Jung SH, Kim DJ, Lee KA
- KMID: 2072513
- Korean J Pediatr Hematol Oncol.
- 2001 Oct;8(2):355-360.
Common variable immunodeficiency (CVID) is a heterogenous syndrome characterized by hypogammaglobulinemia, various immunologic abnormalities and recurrent bacterial infections. Associated immunologic abnormalities consists of various kinds of autoimmune diseases and... -
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- Length diversity in CDR3 Domain of Immunoglobulin Kappa Chain during the Human Deelopment
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Lee JS, Lee SK, Lee CH, Song CH
- KMID: 1928282
- Korean J Immunol.
- 1998 Sep;20(3):309-316.
The third complementarity determining region (CDR3) of the immunoglobulin (Ig) kappa () chain is known to be located at the center of antigen binding groove and critical for antibody specificity.... -
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- Characterization of clonal immunoglobulin heavy (IGH) V-D-J gene rearrangements and the complementarity-determining region in South Indian patients with precursor B-cell acute lymphoblastic leukemia
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Sudhakar N, Rajkumar T, Rajalekshmy KR, Nancy NK
- KMID: 2375205
- Blood Res.
- 2017 Mar;52(1):55-61.
- doi: 10.5045/br.2017.52.1.55
BACKGROUND: This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identified age-related predominance in VDJ rearrangements. METHODS:... -
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- Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library
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Yang W, Yoon A, Lee S, Kim S, Han J, Chung J
- KMID: 2375795
- Exp Mol Med.
- 2017 Mar;49(3):e308.
- doi: 10.1038/emm.2017.22
Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development... -
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- Polymerase Chain Reaction and Sequencing of Immunoglobulin Heavy Chain Gene Rearrangement in Formalin Fixed, Paraffin-embedded Tissue of Patients with B Cell Lymphoma
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Cho SR, Park IJ, Lee MS, Kim EK, Lee WG, Han JH, Park JE, Park JS, Kim HC
- KMID: 2252221
- Korean J Hematol.
- 2007 Dec;42(4):361-366.
- doi: 10.5045/kjh.2007.42.4.361
BACKGROUND: Immunoglobulin heavy chain (IgH) gene rearrangement has been known to be a useful marker for determining the clonality as well as detecting minimal residual disease in B cell malignancies.... -
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- A phosphorylation pattern-recognizing antibody specifically reacts to RNA polymerase II bound to exons
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Han J, Lee JH, Park S, Yoon S, Yoon A, Hwang DB, Lee HK, Kim MS, Lee Y, Yang WJ, Youn HD, Kim H, Chung J
- KMID: 2362295
- Exp Mol Med.
- 2016 Nov;48(11):e271.
- doi: 10.1038/emm.2016.101
The C-terminal domain of RNA polymerase II is an unusual series of repeated residues appended to the C-terminus of the largest subunit and serves as a flexible binding scaffold for... -
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- Human Monoclonal Antibody Inhibiting Reverse Transcriptase Activity of Hepatitis B Virus Polymerase Protein
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Park SJ, Seol SY, Jee SR, Park ET, Lee YJ, Lee SH, Chung JM, Cho HD, Jeong YJ, Choi IH, Park SG
- KMID: 935184
- Korean J Gastroenterol.
- 2007 Feb;49(2):85-92.
BACKGROUND/AIMS: To develop a novel treatment method for hepatitis B virus (HBV) infection, we aimed to make a human monoclonal antibody inhibiting reverse transcriptase (RT) activity of P protein which... -
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