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The prevalence of allergic diseases in school children of metropolitan city in Indonesia shows a similar pattern to that of developed countries

Soegiarto , Abdullah M, Damayanti , Suseno A, Effendi C

BACKGROUND: The prevalence of allergy among Surabaya school children is currently unknown. OBJECTIVE: To identify the prevalence of the common allergic sensitization and allergic diseases among school children and undergraduate students...
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German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells

Lee KE, Jee HM, Hong JY, Kim MN, Oh MS, Kim YS, Kim KW, Kim KE, Sohn MH

PURPOSE: Cockroach exposure is a pivotal cause of asthma. Tight junctions are intercellular structures required for maintenance of the barrier function of the airway epithelium, which is impaired in this...
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Aeroallergen sensitization and associated comorbid diseases of an adult Filipino population with allergic rhinitis

Navarro-Locsin CG, Lim-Jurado M

BACKGROUND: There is a large global variation in sensitization patterns to aeroallergens due to differences in climate, urbanization, and lifestyle. Knowledge of the most common inhalant allergens is important for...
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Relation of allergic rhinitis, allergen sensitization, and air pollutants in preschool children

Kim YJ, Yoon SA, Woo SI

PURPOSE: We aimed to investigate the prevalence and allergen sensitization of allergic rhinitis (AR) in preschool children. We assessed the relationship of AR, allergen sensitization, and air pollutants. METHODS: Between 2012...
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Dembo polymerase chain reaction technique for detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs

Rahpaya SS, Tsuchiaka , Kishimoto , Oba M, Katayama Y, Nunomura Y, Kokawa S, Kimura T, Kobayashi , Kirino Y, Okabayashi T, Nonaka N, Mekata H, Aoki H, Shiokawa M, Umetsu M, Morita T, Hasebe A, Otsu K, Asai T, Yamaguchi , Makino S, Murata Y, Abi AJ, Omatsu T, Mizutani T

Bovine abortion, diarrhea, and respiratory disease complexes, caused by infectious agents, result in high and significant economic losses for the cattle industry. These pathogens are likely transmitted by various vectors...
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Skin prick test reactivity to aeroallergens in adult allergy clinic in Thailand: a 12-year retrospective study

Oncham S, Udomsubpayakul U, Laisuan W

BACKGROUND: The global prevalence of allergic rhinitis, asthma, and atopic dermatitis has risen significantly over the last 2 decades. Allergic sensitization to aeroallergen is a major risk factor in developing...
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Accuracy of serum-specific IgE test with microfluidic array enzyme-linked immunosorbent assay for diagnosing inhalant allergen sensitization in asthma and/or rhinitis allergy patients in Jakarta, Indonesia

Sinurat J, Rengganis , Rumende CM, Harimurti

BACKGROUND: Asthma and allergic rhinitis are a global health burden. Inhalant allergens worsen the symptoms and clinical manifestations of asthma and allergic rhinitis. Skin prick test is the gold standard...
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Association Between Sensitization to Mold and Impaired Pulmonary Function in Children With Asthma

Byeon JH, Ri S, Amarsaikhan O, Kim E, Ahn SH, Choi IS, Kim HJ, Seo S, Yoon W, Yoo Y

PURPOSE: Recent data indicate that sensitization to mold contributes to the severity and persistence of asthma. In this study, we investigated the relationships between sensitization to mold and lung function...
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Patterns of Inhalant Allergen Sensitization and Geographical Variation in Korean Adults: A Multicenter Retrospective Study

Kang MG, Kim MY, Song WJ, Kim S, Jo EJ, Lee SE, Kwon JW, Lee SM, Park CS, Park HK, Park HW, Chang YS, Lee J, Lee YM, Jee YK, Lee JM, Choi IS, Cho SH

PURPOSE: Inhalant allergen sensitization is one of the major factors involved in the pathogenesis of allergic respiratory diseases. However, the sensitization is determined by interactions between genetic and environmental factors....
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Prevalence of Allergic Disease in Korean Adults: Results from the Korea National Health and Nutrition Examination Survey (2010–2012)

Im D, Yang YS, Choi HR, Choi S, Nahm H, Han K, Hong SC, Kim JK, Cho JH

BACKGROUND AND OBJECTIVES: In this study, we evaluated differences in the prevalence of allergic rhinitis, asthma, atopic dermatitis and specific immunoglobuline E (IgE) value for some respiratory antigens in Korean...
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Sensitization to common allergens among patients with allergies in major Iranian cities: a systematic review and meta-analysis

Moghtaderi M, Hosseini Teshnizi S, Farjadian

Various allergens are implicated in the pathogenesis of allergic diseases in different regions. This study attempted to identify the most common allergens among patients with allergies based on the results...
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Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-induced asthma model

Park S, Chung HS, Shin D, Jung KH, Lee H, Moon J, Bae H

Foxp3 is a master regulator of CD4⁺CD25⁺ regulatory T-cell (Treg) function and is also a suppressor of SKP2 and HER2/ErbB2. There are an increasing number of reports describing the functions...
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CpG Oligodeoxynucleotide Inhibits Cockroach-Induced Asthma via Induction of IFN-gamma+ Th1 Cells or Foxp3+ Regulatory T Cells in the Lung

Kim DH, Sohn JH, Park HJ, Lee JH, Park JW, Choi JM

PURPOSE: CpG oligodeoxynucleotide (CpG-ODN), a TLR9 agonist, activates innate immunity and induces Th1 response. Although the immune modulatory effect of CpG-ODN has been extensively studied, its function in cockroach extract-induced...
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Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin?

Wong L, Huang CH, Lee BW

Crustacean shellfish allergy is an important cause of food allergy and anaphylaxis in Asia. The major allergen in shellfish allergy is tropomyosin, a pan-allergen that is also found in house...
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Environmental Exposure and Genetic Predisposition as Risk Factors for Asthma in China

Chen Y, Wong GW, Li J

Asthma is the most common chronic pulmonary disease worldwide and places a considerable economic burden on society. China is the world's largest developing country and has the largest population. China...
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IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2

Lee MF, Chang CW, Song PP, Hwang GY, Lin SJ, Chen YH

PURPOSE: Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there...
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Allergenic Characterization of a Novel Allergen, Homologous to Chymotrypsin, from German Cockroach

Jeong KY, Son M, Lee JH, Hong CS, Park JW

PURPOSE: Cockroach feces are known to be rich in IgE-reactive components. Various protease allergens were identified by proteomic analysis of German cockroach fecal extract in a previous study. In this...
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Bacterial PAMPs and Allergens Trigger Increase in [Ca2+]i-induced Cytokine Expression in Human PDL Fibroblasts

Son GY, Shin DM, Hong JH

An oral environment is constantly exposed to environmental factors and microorganisms. The periodontal ligament (PDL) fibroblasts within this environment are subject to bacterial infection and allergic reaction. However, how these...
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Risk factors of allergic sensitization in preschool children with chronic cough

Lee ES, Bang JS, Oh YJ, Lee JW, Sung TJ, Lee YJ, Lee KH

PURPOSE: Chronic cough is one of the major symptoms of asthma and allergic sensitization and may appear prior to the onset of asthma. The object of this study was to...
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Comparison of skin prick test and serum specific IgE measured by ImmunoCAP system for various inhalant allergens

Nam YH, Jeon DS, Lee SK

PURPOSE: It appears that much of the discordance between skin prick test (SPT) and ImmunoCAP in clinical practice. We investigated the comparison and correlation between SPT and ImmunoCAP for inhalant...
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