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Metabolic disease as a risk of hepatocellular carcinoma

Nishida N

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Alcohol-related cirrhosis: The most challenging etiology of cirrhosis is more burdensome than ever

Tonon M, Piano S

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Elimination of hepatitis C: What would be the practical approach?

Yim HJ

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Old hepatitis B virus never dies: It just hides itself within the host genome

Lee JH

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A dilemma that probably would never resolve

Thanage R, Jain S, Chandnani S, Rathi P

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Exploring the mythical abscopal effect: Radiation and programmed cell death protein 1 (PD-1) blockade for hepatocellular carcinoma

Kim JW, Lee IJ

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Outcomes of Hepatitis C Virus Treatment with Ledipasvir/Sofosbuvir in Mongolian Population: Successes and Challenges Facing Scale-up of Care

Kang SH, Kim MY

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The cutoff of transient elastography for the evaluation of portal hypertension should be different according to the etiology?

Kim BK

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Drug-drug interactions with direct-acting antivirals — less is more

Wong GLH

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Probiotics for treatment of nonalcoholic fatty liver disease: It is worth a try

Ren TY, Li XY, Fan JG

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Scaling up the in-hospital hepatitis C virus care cascade in Taiwan

Huang CF, Wu PF, Yeh ML, Huang CI, Liang PC, Hsu CT, Hsu PY, Liu HY, Huang YC, Lin ZY, Chen SC, Huang JF, Dai CY, Chuang WL, Yu ML

Background/Aims: Obstacles exist in facilitating hepatitis C virus (HCV) care cascade. To increase timely and accurate diagnosis, disease awareness and accessibility, in-hospital HCV reflex testing followed by automatic appointments and...
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Recent updates on the management of autoimmune hepatitis

Komori A

Autoimmune hepatitis (AIH) is an immunoinflammatory chronic liver disease with dynamic and rather heterogeneous disease manifestations. A trend of increasing prevalence of AIH has been observed worldwide, along with a...
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Current understanding of primary biliary cholangitis

Tanaka A

Primary biliary cholangitis (PBC) causes chronic and persistent cholestasis in the liver, eventually resulting in cirrhosis and hepatic failure without appropriate treatment. PBC mainly develops in middle-aged women, but it...
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The development of mesenchymal stem cell therapy in the present, and the perspective of cell-free therapy in the future

Watanabe Y, Tsuchiya A, Terai S

Cirrhosis is a chronic condition that can lead to liver failure. Currently, the viable option for decreasing mortality is liver transplantation. However, transplant surgery is highly invasive. Therefore, cell-based therapy...
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Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance

Jang JW, Kim JS, Kim HS, Tak KY, Nam H, Sung PS, Bae SH, Choi JY, Yoon SK, Roberts LR

Background/Aims: The role of hepatitis B virus (HBV) integration into the host genome in hepatocarcinogenesis following hepatitis B surface antigen (HBsAg) seroclearance remains unknown. Our study aimed to investigate and...
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The role of the gut microbiome and diet in the pathogenesis of non-alcoholic fatty liver disease

Jennison E, Byrne CD

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease, with a prevalence that is increasing in parallel with the global rise in obesity and type 2...
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Alcohol associated liver cirrhotics have higher mortality after index hospitalization: Long-term data of 5,138 patients

Jain P, Shasthry SM, Choudhury AK, Maiwall R, Kumar G, Bharadwaj A, Arora V, Vijayaraghavan R, Jindal A, Sharma MK, Bhatia V, Sarin SK

Background/Aims: Liver cirrhosis is an important cause of morbidity and mortality globally. Every episode of decompensation and hospitalization reduces survival. We studied the clinical profile and long-term outcomes comparing alcohol-related...
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Updates in the quantitative assessment of liver fibrosis for nonalcoholic fatty liver disease: Histological perspective

Soon G, Wee A

Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) is a major cause of liver fibrosis and cirrhosis. Accurate assessment of liver fibrosis is important for predicting disease outcomes and assessing therapeutic response...
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Efficacy and safety of ledipasvir/sofosbuvir in 5,028 Mongolian patients infected with genotype 1 hepatitis C virus: A multicenter study

Baatarkhuu O, Lee JS, Amarsanaa J, Kim DY, Ahn SH, Naranzul N, Enkhtuya D, Choijamts N, Batbayar P, Otgonbayar R, Saruul BU, Gantuul C, Gegeebadrakh B, Tuvshinbayar N, Badamsuren D, Ulzmaa G, Otgonbold J, Han KH

Background/Aims: Ledipasvir/sofosbuvir (LDV/SOF) shows high efficacy and safety in patients with genotype 1-hepatitis C virus (HCV). We aimed to investigate the efficacy and safety of LDV/SOF in real-world Mongolian patients. Methods:...
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Radiation-induced abscopal effect and its enhancement by programmed cell death 1 blockade in the hepatocellular carcinoma: A murine model study

Yoo GS, Ahn WG, Kim SY, Kang W, Choi C, Park HC

Background/Aims: The abscopal effect, a rare phenomenon induced by radiation, can be reinforced by immunotherapy. Although radiation therapy and immunotherapy are increasingly being utilized for the treatment of hepatocellular carcinoma...
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