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Clinical characteristics and associated factors of pediatric acute necrotizing encephalopathy: a retrospective study

Zhang H, Wang Y, Ding Q, Li X, Ye S

Background: In the clinic, pediatric acute necrotizing encephalopathy (ANE) primarily affects children under 5 years of age and is characterized by severe brain damage and high mortality. However, some challenges...
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Promising role of voxelotor in managing sickle cell disease in children: a narrative review

Agrawal A, Jadon G, Singh J, Janjua D

Sickle cell disease (SCD) is characterized by chronic hemolytic anemia and intermittent vasoocclusive crises. To date, 4 disease-modifying drugs have been approved for the treatment of SCD: hydroxyurea (an S-phase...
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Evaluation of pediatric migraine triggers: a single-center study

Son HJ, Jin JO, Lee KH

Background: Pediatric migraines are primarily treated with medications. However, recognizing the triggers related to patient behaviors and lifestyle is also important. Purpose: This study aimed to evaluate the factors that trigger...
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Differences in immune cells and gene expression in human milk by parity on integrated scRNA sequencing

Yi DY, Park HJ, Shin MS, Kim H, Lee SJ, Kang I

Background: Human breast milk (HBM) is an important source of tolerogenic immune mediators that influence the infant immune system. HBM-derived immune components are affected by various factors; however, few studies...
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Effect of high-frequency oscillatory ventilation with intermittent sigh breaths on carbon dioxide levels in neonates

Baingam K, Thatrimontrichai A, Praditaukrit M, Maneenil G, Dissaneevate S

Background: High-frequency oscillatory ventilation (HFOV) minimizes ventilator-induced lung injuries. Spontaneous sigh breathing may augment the functional residual capacity, increase lung compliance, and recruit atelectatic alveoli. Purpose: To evaluate the difference in...
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Characteristics of temper tantrums in 1–6-year-old children and impact on caregivers

Prutipaisan W, Chunsuwan I, Hansakunachai T, Sritipsukho P

Background: Temper tantrums are common behavioral difficulties in children. Although they are generally considered a normal part of development, certain characteristics— such as aggression, prolonged duration, and frequent occurrences—have been...
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Absolute versus functional iron deficiency

Jung HL

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Effect of metabolic syndrome on pulmonary dysfunction in children with asthma

Kim HB

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Value of transabdominal ultrasonography for diagnosing functional constipation in children: a systematic review and meta-analysis

Tran DL, Nguyen Trong Tran P, Susantitaphong P, Phinyo P, Sintusek P

Transabdominal ultrasonography is increasingly used as a novel modality for detecting pediatric functional constipation (FC). This systematic review and metaanalysis aimed to assess the diagnostic parameters of FC including rectal...
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Prevalence of childhood overweight and obesity in Malaysia: a systematic review and meta-analysis

Chua KY, Chua KY, Chinna K, Lim CL, Seneviwickrama M

The incidence of childhood obesity is increasing worldwide. National surveys in Malaysia have shown similar trends. This review aimed to increase our understanding of the prevalence and associated factors of...
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