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Anemia Can Be Associated with Isovaleric Acidemia

Yoon JH, Lee HJ

No abstract available.
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A Case of Successfully Treated Severe Heart Failure due to Cyclophosphamide Induced Cardiomyopathy

Park JM, Hahn SM, Han JW, Lyu CJ

Cyclophosphamide-induced cardiotoxicity is an uncommon complication especially in patients who have never undergone mediastinal irradiation or cardiotoxic chemotherapy and do not have underlying cardiac diseases. Here, we describe the case...
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A Case of Erdheim-Chester Disease Developed during Treatment of Leukemia in a Child

Hong JP, Ahn WK, Lim JY, Jung JE, Hahn SM, Han JW, Lyu CJ

Erdheim-Chester disease (ECD) is a rare non-Langerhan's cell histiocytosis disorder characterized by replacement of normal tissue by lipid-laden histiocytes affecting various organs. A few pediatric cases have been reported worldwide....
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Septic Arthritis and Infective Endocarditis in an Adolescent Hemophilia B Patient with an Inhibitor and a Central Venous Access Device

Kim J, Park YS

Central venous access devices (CVAD) provide hemophilic patients, particularly children, with prolonged reliable venous access to promote routine factor replacement therapy. However, one of the significant complications of CVAD use...
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A Case of Jacobsen Syndrome Presenting with a Huge Cephalhematoma and Thrombocytopenia after Birth

Shin J, Kim G, Lee R, Jung N, Shim YJ, Ha JS

Jacobsen syndrome (JS) is a contiguous gene syndrome resulting from a deletion of chromosome 11q, with various clinical manifestations. A post-term small for gestational age infant was born by normal...
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Effects of Low- or Moderate-dose Whole Body-X-ray Radiation on the Immune System of C57BL/6 Mice

Ko Y, Jeong YH, Lee JA

PURPOSE: Increase in the use of diagnostic imaging or occupational exposure to radiation have brought upon concerns on the safety and biological effects of low- or moderate-dose radiation. However, limited...
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Childhood Venous Thromboembolism in Yeungnam Region in Korea: Multicenter Study

Lee S, Youn JH, Lim JY, Chueh HW, Lee JM, Suh JK, Kim JY, Yang EJ, Park KM, Lim YT, Park J, Choi EM, Shim YJ, Kim HS, Park SK, Kong SG, Choi EJ, Park ES

BACKGROUND: Venous thromboembolism (VTE) is rare in pediatric patients compared to adults, but it's incidence is gradually increasing. The purpose of this study was to analyze the incidence, risk factors,...
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Educational Interventions to Enhance Adherence to Prophylactic Treatment in Korean Hemophilia Patients

Na JH, Yoo KY, Kim JY, Park SK, Kim SK, Choi EJ

BACKGROUND: A patient's adherence to prophylactic treatment is one of the most significant factors to achieve desired outcomes, in regards to the quality of life and treatment cost-effectiveness. The aim...
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Family History as a Risk Factor for Iron Deficiency Anemia among Korean Adolescents: Data from the Fifth Korea National Health and Nutrition Examination Survey (KNHANES)

Chueh HW, Choi YC, Shin JH, Yoo JH

BACKGROUND: Iron deficiency anemia (IDA) is a disease prevalent throughout the world. However, there is limited information regarding whether familial factors are associated with the risk of adolescent IDA. METHODS: This...
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Understanding the Molecular Basis of Juvenile Myelomonocytic Leukemia and Its Application for Novel Drugs Development

Jeon IS

To date, hematopoietic stem cell transplantation (HSCT) is the only choice of therapy for most patients with juvenile myelomonocytic leukemia (JMML). Relapse remains a major problem. Approximately 90% of patients...
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Progress of Hemophilia A Therapeutics in Korea

Kim DH, Kim SK

Over the past several decades, hemophilia treatment in Korea has progressed dramatically. It has become possible to prevent hemophilia complications by maintenance treatment as well as on-demand treatment with the...
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Diagnostic Approach of Childhood Immune Thrombocytopenia

Kim JY

Immune thrombocytopenia (ITP) is the most common cause of thrombocytopenia in children and can be defined as an autoimmune disorder of isolated thrombocytopenia without other causes of thrombocytopenia. This review...
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Basic Understanding of Iron Metabolism

Suh JK, Jeon IS

Iron is critical for almost all living organisms because it serves as a cofactor for many proteins and enzymes necessary for oxygen and energy metabolism. Disruption of iron homeostasis is...
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