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Three Cases of Pulmonary Hemosiderosis with Long-term Treatment of Deflazacort in Children

Park K, Yoo Y, Pai K, Park JE

Idiopathic pulmonary hemosiderosis (IPH) is a rare respiratory disease with an unknown etiology, and is diagnosed with laboratory, radiology, and pathology tests. Chief complaints of IPH include hemoptysis, cough, and...
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A Case of Hodgkin Lymphoma Developed in an Ataxia-telangiectasia Patient

Lim JY, Jeon M, Kim HS, Han JW, Lyu CJ, Hahn SM

Ataxia-telangiectasia (AT) is characterized by cerebellar ataxia, progressive immunodeficiency, radiation sensitivity, telangiectasia, and predisposition to malignancy. AT patients have a 100-fold increased risk for the development of lymphoid malignancies. It...
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Adenovirus-induced Hemophagocytic Lymphohistiocytosis in a Previously Healthy Boy: A Case Report and Literature Review

Seo YH, Shim YJ, Kim HS, Lee HJ, Jeon DS, Im HJ

A 3-year-old previously healthy boy was admitted because of a 1-week history of fever, abdominal pain, vomiting, and diarrhea. The initial laboratory tests showed hepatic dysfunction with disseminated intravascular coagulation....
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A Case of Neonatal Langerhans Cell Histiocytosis Presenting with Generalized Skin Involvement at Birth Evolving to Hepatic Involvement

Park IS, Park JE, Lee JH

Langerhans cell histiocytosis (LCH) is a rare disease having an unknown etiology, but characterized by a disorder of antigen presenting cells and the mononuclear phagocytic system. Neonatal LCH, defined as...
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Case Report of Inferior Vena Cava Agenesis Accompanying Deep Vein Thrombosis

Lee DH, Lee YM, Park KB, Suh WS, Hong HS

A 17-year-old male patient was admitted to the author's hospital complaining of pain in both flanks. He had a history of being admitted to a tertiary-level hospital a year before,...
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A Case of Myosin-heavy-chain-9 (MYH9) Gene Mutation Confirmed May-Hegglin Anomaly: 11-year Follow-up

Park SJ, Wy H, Jung HL, Shim JW, Shim JY, Kim DS, Park MS, Seo SH, Seong MW

May-Hegglin anomaly (MHA) is a myosin-heavy-chain-9 (MYH9)-related disorder characterized by thrombocytopenia with giant platelets and inclusion bodies in leukocytes. MHA does not require treatment, but it may be misdiagnosed as...
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Autoimmune Hemolytic Anemia after Intravenous Immunoglobulin Therapy in a Child with Kawasaki Disease

Moon JW, Lee SH, Oh YK, Choi DY, Yu ST

Kawasaki disease (KD) can cause acquired heart disease and systemic vasculitis in children. It is treated with intravenous immunoglobulin (IVIG). A significant complication is development of coronary artery lesions such...
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Massive Fetomaternal Hemorrhage Diagnosed with High-performance Liquid Chromatography

Lee JY, Kim KH, Kong SG

Massive fetomaternal hemorrhage (FMH) is a major cause of unexplained fetal death and neonatal anemia. FMH can be diagnosed using the Kleihauer-Betke test or flow cytometry by identifying the presence...
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Outcomes of Hematopoietic Stem Cell Transplantation by Donor Types in Children with Acute Myeloid Leukemia

Choe HY, Kim G, Lee WJ, Choi JS, Baek HJ, Kook H

BACKGROUND: The aim of this study was to compare the outcomes of children with acute myeloid leukemia (AML) who received stem cell transplantation from different donor groups. METHODS: This study included...
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Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Genetic Rare Diseases in Children

Lee WJ, Kim G, Choi JS, Baek HJ, Kook H

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) has been established as an important curative method in genetic rare diseases in children. However, adverse effects have been obstacles for successful outcomes. This...
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Clinical Applicability of Newly Developed Image-based Cell Counter for Counting CD34+ Cells: Comparison with Flow Cytometric Analysis

Rah WJ, Shin EK, Koh H, Suh JY, Chang M, Nam E, Oh JH, Jung Y, Lee JY, Bong SR, Hong SH, Kim JY, Han S, Hwang JK, Chung C, Lee YH

BACKGROUND: Flow cytometric analysis is the standard method for enumerating CD34+ stem cells in hematopoietic stem cell transplantation. However, it has some limitations such as expensive instrumentation, high reagent costs,...
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Rare Non-Hodgkin Lymphoma in Childhood; A Single Center Experience

Kim HJ, Lee D, Koh KN, Kang SH, Kim H, Im HJ, Seo JJ

BACKGROUND: Among pediatric non-Hodgkin lymphomas, there are 4 major subtypes: Burkitt lymphoma, lymphoblastic lymphoma, diffuse large B-cell lymphoma, and anaplastic large-cell lymphoma. Understanding of other rare subtypes derives only from...
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Characteristics and Therapeutic Outcomes of Acute Promyelocytic Leukemia in Children and Adolescents

Kim G, Lee HO, Choi JS, Baek HJ, Kook H

BACKGROUND: Acute promyelocytic leukemia (APL) is rare in children, accounting for 5-7% of all acute myeloid leukemia (AML) cases. This study aimed to review clinical and laboratory characteristics of pediatric...
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Propranolol as a First-line Treatment for Pediatric Hemangioma: Outcome of a Single Institution Over One Year

Kim KM, Min DH, Jung HL, Shim JW, Kim DS, Shim JY, Park MS, Park HJ, Lee SY

BACKGROUND: Propranolol, a beta-blocker and well known anti-hypertensive medication, has been used as the first-line therapy for pediatric hemangioma since 2010. The objective of this study is to analyze the...
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A Study of Home Therapy in Hemophilia Patients

Moon HS, Huh JS, Lee OK, Kim MK

BACKGROUND: Home therapy has merits, enabling rapid treatment thereby reducing complications, but difficulty with venous access is a barrier to treatment. There is a paucity of data on this. This...
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Neutrophil to Lymphocyte Ratio (NLR) as a Predictive Marker for Prognosis in the Patients with Immune Thrombocytopenic Purpura (ITP)

Yang GE, Lee MJ, Yoo JH, Chueh HW

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an autoimmune disorder presenting low platelet count in peripheral blood without any other abnormalities in other blood cell lineage. There were many studies that...
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Iron Contents in Rice Food Derived from the Iron Pot, and In Vitro Study Regarding Heme Oxygenase-1 Activity

Kim KY, An YM, Kim TW, Jun YH, Lee JE, Jang JH, Kim SK

BACKGROUND: Iron pots have long been used for cooking in several countries. Early studies have shown that the use of such iron pots can increase the iron content of food...
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Anti-GD2 Monoclonal Antibody (dinutuximab) with GM-CSF, Interleukin 2, and Cis-retinoic Acid for the Treatment of High-risk Neuroblastoma

Jeon IS

Neuroblastoma, one of the most common solid tumors in early childhood, exhibits aberrant cell-surface glycosylation patterns. In neuroblastoma, disialoganglioside (GD2) is expressed homogeneously and abundantly on 100% of neuroblastoma cells....
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