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Clinical Characteristics and Treatment Outcomes of Non-anaplastic Peripheral T-Cell Lymphoma in Children and Adolescents: A Single-center Experience

Lee D, Koh KN, Byun Y, Kim HJ, Suh JK, Lee SW, Im HJ, Seo JJ

BACKGROUND: Peripheral T-cell lymphoma (PTCL) is a rare form of non-Hodgkin's lymphoma (NHL), and it is usually associated with poor outcome. Here, we report our experience in treating this disease...
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A Case Report of Solitary Fibrous Tumor in the Axilla of a 4-year-old Girl with Additional Marker Chromosome

Park JH, Kim EJ, Noh OK, Jung HJ, Park JE

Solitary fibrous tumor (SFT) is uncommon and known to affect in middle-aged adults, with rare reports of occurrences in children. Although frequently involving the pleura, recent reports show that SFT...
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A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm in a Child

Park KM, Yang EJ, Seo JH, Shin DH, Lim YT

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare hematological malignancy in children that is characterized by bruise-like skin lesions, with or without bone marrow involvement. Because the clinical...
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A Huge Anterior Mediastinal Thymoma of an Infant: A Case Report

Hwang IK, Hahn SM, Kim HS, Han JW, Lyu CJ

A seven months old male infant visited Severance Children's Hospital for evaluation of anterior mediastinal mass. With chest computed tomography (CT) image and biopsy, precursor T-cell lymphoblastic lymphoma was suspected...
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Two Cases of Infant Hemophilia A Patients with Inhibitors

Yu DU, Park JK, Park YS

Development of inhibitors is currently one of the most serious complications of hemophilia treatment. Typically, the propensity to develop an inhibitor is likely influenced by both genetic and non-genetic factors....
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The Benefit for Preoperative Coagulation Screening Test in Children

Park JH, Yoo KY, Jung HJ, Park JE

BACKGROUND: We evaluated the value of preoperative screening for coagulopathy in children who have undergone elective surgery. METHODS: We retrospectively evaluated laboratory and bleeding histories in 39,884 patients aged greater than...
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Spontaneous Remission in a Teenage Girl with Acquired Pure Red Cell Aplasia

Kwon SE, Kwon HW, Kim DH, Moon Y, Hong YJ, Kim SK

Acquired pure red cell aplasia (PRCA) can be induced by various factors such as viral infection, thymoma, connective tissue disease, lymphoma, and adverse drug reactions. PRCA has not been reported...
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Hereditary Antithrombin Deficiency with Hemorrhagic Cerebral Infarction and Cardiac Thrombosis Occurred in Neonatal Period: A Case Report

Park JS, Choi YJ, Hahn SM, Kim HS, Han JW, Oh SH, Lyu CJ

Antithrombin (AT) is the main inhibitor of blood coagulation proteases. Hereditary AT deficiency is an autosomal-dominant thrombophilic disorder caused by a SERPINC1 abnormality, it represents a risk factor for thromboembolic...
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Clinical Characteristics and Treatment Outcome of the Desmoplastic Small Round Cell Tumor

Lee HJ, Choi JY, Hong CR, Lee JW, Kang HJ, Park KD, Shin HY, Ahn HS

BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is an aggressive malignancy with a poor prognosis. DSRCT is a rare disease, and therefore a standard treatment regimen has not been established....
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Tacrolimus and Mini-dose Methotrexate for Prevention of Graft-Versus-Host Disease after Unrelated Hematopoietic Stem Cell Transplantation in Children: A Single-center Study in Korea

Yang EJ, Park KM, Seo JH, Lim YT

BACKGROUND: Currently, data on the role of tacrolimus and mini-dose methotrexate (MTX) in pediatric unrelated hematopoietic stem cell transplantation (HSCT) is limited. We report the outcomes of unrelated hematopoietic stem...
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Bronchiolitis Obliterans Syndrome after Allogenic Hematopoietic Stem Cell Transplantation in Pediatric Patients

Lim JY, Hahn SM, Kim HS, Han JW, Lyu CJ

BACKGROUND: Bronchiolitis obliterans syndrome (BOS) is a life-threatening lung complication after allogenic hematopoietic stem cell transplantation (HSCT). As long-term survival following allogenic HSCT has improved, the number of BOS patients...
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A Hypervascular Inflammatory Myofibroblastic Tumor in the Mediastinum Resected Completely Following Embolization of the Feeding Vessels

Kang HN, Shin EJ, Rah WJ, Yoon K, Song SY, Jeon SC, Lee JH, Jung WS, Jang K, Lee YH

Inflammatory myofibroblastic tumors (IMTs) are rare tumors of intermediate malignant potential that can occur anywhere in the body. We describe an interesting case of a hypervascular IMT in the mediastinum...
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Lupus Anticoagulant-hypoprothrombinemia Syndrome that did not Progress to Systemic Lupus Erythematosus: A Case Report

Hwang YE, Park HK, Yeom JS, Park JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS

Lupus anticoagulant-hypoprothrombinemia syndrome (LA-HPS) is a rare disorder, and appears mostly in children. The primary concern is its potential development into systemic lupus erythematosus (SLE). A 5-year-old patient was hospitalized...
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A Case of Long-term Survival with Autologous Recovery after Double Cord Blood Transplantation for Juvenile Myelomonocytic Leukemia

Lee HJ, Choi JY, Hong CR, Lee JW, Kang HJ, Park KD, Shin HY, Ahn HS

A 1.1 year old boy was admitted to the Seoul National University Children's Hospital because of incidental findings of hepatosplenomegaly, skin lesion and multiple intra- abdominal lymphadenopathies. Anemia and thrombocytopenia...
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A Case of Kasabach-Merritt Syndrome Successfully Treated with Interferon-alpha 2b and Propranolol

Lee JW, Jung HL, Shim JW, Kim DS, Shim JY, Park MS, Park HJ

Kasabach-Merritt syndrome (KMS) is a rare, life-threatening disease characterized by rapidly enlarging hemangioma and consumptive coagulopathy. We report a case of KMS in a 28-day-old female neonate with a huge...
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Evaluation of Immune Response after Vaccinations Post-chemotherapy in Childhood Cancer Survivors

Shin EJ, Rah WJ, Lee YH

BACKGROUND: Survivors of childhood cancers are recommended to receive revaccinations after chemotherapy, although the universally recommended vaccination schedule for such children has not been established. We evaluated immune response following...
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Invasive Pulmonary Aspergillosis after Recent Influenza in a Child with Acute Myeloid Leukemia

Kim BJ, Kim SK, Han SB, Lee JW, Yoon JS, Chung NG, Cho B, Kang JH, Kim HK

Respiratory viral infection has been reported as a risk factor for invasive pulmonary aspergillosis (IPA) in hematopoietic cell transplantation (HCT) recipients, and IPA following influenza has been reported. We report...
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Comparison of Survival by Risk-stratified Therapy in Children and Adolescents with Acute Lymphoblastic Leukemia in a Single Institute

Oh HJ, Cheon KR, Jang HI, Cho JH, Jeong K, Baek HJ, Kook H

BACKGROUND: Impressive improvement of survival rate has been achieved in childhood acute lymphoblastic leukemia (ALL). In an effort to balance the risks and benefits of therapy, risk-stratified therapy has been...
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