- Salternamide E from a Saltern-derived Marine Actinomycete Streptomyces sp.
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Kim SH, Shin Y, Lee SK, Shin J, Oh DC
- KMID: 2312909
- Nat Prod Sci.
- 2015 Dec;21(4):273-277.
- doi: 10.20307/nps.2015.21.4.273
Comprehensive chemical analysis of extracts and fractions of marine actinomycete strains led to the discovery of a new minor secondary metabolite, salternamide E (1), from a saltern-derived halophilic Streptomyces strain.... -
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- Cooperative binding interaction of ethidium with allosteric DNA
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Suh D
- KMID: 755044
- Exp Mol Med.
- 1999 Sep;31(3):151-158.
The specific association of drugs with deoxyoligonucleotides, containing a B-Z junction between left-handed Z-DNA and right-handed B-DNA, was examined by fluorescence and circular dichroism (CD) technique. Ethidium was chosen for a simple DNA... -
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- D-RADA16-RGD-Reinforced Nano-Hydroxyapatite/Polyamide 66 Ternary Biomaterial for Bone Formation
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Zhao W, He B, Zhou A, Li Y, Chen X, Yang Q, Chen B, Qiao B, Jiang D
- KMID: 2449248
- Tissue Eng Regen Med.
- 2019 Apr;16(2):177-189.
- doi: 10.1007/s13770-018-0171-5
BACKGROUND: Nano-hydroxyapatite/polyamide 66 (nHA/PA66) is a composite used widely in the repair of bone defects. However, this material is insufficient bioactivity. In contrast, D-RADA16-RGD self-assembling peptide (D-RADA16-RGD sequence containing all... -
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- Binding Specificity of Philyra pisum Lectin to Pathogen-Associated Molecular Patterns, and Its Secondary Structure
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Park BT, Kim BS, Park H, Jeong J, Hyun H, Hwang HS, Kim HH
- KMID: 2285483
- Korean J Physiol Pharmacol.
- 2013 Dec;17(6):547-551.
- doi: 10.4196/kjpp.2013.17.6.547
We recently reported a Philyra pisum lectin (PPL) that exerts mitogenic effects on human lymphocytes, and its molecular characterization. The present study provides a more detailed characterization of PPL based... -
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- The N-terminal 1-16 peptide derived in vivo from protein seminal vesicle protein IV modulates alpha-thrombin activity: potential clinical implications
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Lepretti M, Costantini S, Ammirato G, Giuberti G, Caraglia M, Facchiano , Metafora S, Stiuso P
- KMID: 1104808
- Exp Mol Med.
- 2008 Oct;40(5):541-549.
- doi: 10.3858/emm.2008.40.5.541
We have previously shown that seminal vesicle protein IV (SV-IV) and its 1-70 N-terminal fragment have anti-inflammatory activity and modulate anti-thrombin III (AT) activity. Moreover, mass spectrometry analysis of purified... -
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- Effect of Amino Acid Polymorphisms of House Dust Mite Der p 2 Variants on Allergic Sensitization
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Tanyaratsrisakul S, Jirapongsananuruk O, Kulwanich , Hales BJ, Thomas WR, Piboonpocanun S
- KMID: 2166650
- Allergy Asthma Immunol Res.
- 2016 Jan;8(1):55-62.
- doi: 10.4168/aair.2016.8.1.55
PURPOSE: The sequence variations of the Der p 2 allergen of Dermatophagoides pteronyssinus diverge along 2 pathways with particular amino acid substitutions at positions 40,47,111, and 114. The environmental prevalence... -
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- A Novel Heterozygous Missense Variant (c.667G>T;p.Gly223Cys) in USH1C That Interferes With Cadherin-Related 23 and Harmonin Interaction Causes Autosomal Dominant Nonsyndromic Hearing Loss
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Song JS, Bahloul A, Petit C, Kim SJ, Moon IJ, Lee J, Ki CS
- KMID: 2466015
- Ann Lab Med.
- 2020 May;40(3):224-231.
- doi: 10.3343/alm.2020.40.3.224
BACKGROUND: Pathogenic variants of USH1C, encoding a PDZ-domain-containing protein called harmonin, have been known to cause autosomal recessive syndromic or nonsyndromic hearing loss (NSHL). We identified a causative gene in... -
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- Environments of ethidium binding to allosteric Dna: II. Accessibility, mobility and mode of binding
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Suh DC
- KMID: 755100
- Exp Mol Med.
- 2000 Dec;32(4):204-209.
DNA binding compounds were previously shown to bind to the right-handed DNA forms and hybrid B-Z forms in a highly cooperative manner and indicate that structural specificity plays... -
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- Structure and Function of a Minimal Receptor Activation Domain of Parathyroid Hormone
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Lee EJ, Kim HY, Cho MK, Lee W, Lim SK
- KMID: 1734123
- Yonsei Med J.
- 2004 Jun;45(3):419-427.
- doi: 10.3349/ymj.2004.45.3.419
The structure and function of short-length amino terminal PTH analogues were studied. The substitution of Leu7 with Phe in [Ala3, 10Leu7Arg11]rPTH (1-11) NH2 analogue peptides did not show any reduction... -
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- Purification and characterization of recombinant murine endostatin in E. coli
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You WK, So SH, Lee H, Park SY, Yoon MR, Chang SI, Kim HK, Joe YA, Hong YK, Chung SI
- KMID: 1029927
- Exp Mol Med.
- 1999 Dec;31(4):197-202.
Endostatin, a carboxyl-terminal fragment of collagen XVIII is known as an anti-angiogenic agent, that specifically inhibits the proliferation of endothelial cell and the growth of several primary tumor.... -
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- Structure-activity relationships of anti-HIV-1 peptides with disulfide linkage between D- and L-cysteine at positions i and i+3, respectively, derived from HIV-1 gp41 C-peptide
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Lee MK, Kim HK, Lee TY, Hahm KS, Kim KL
- KMID: 1105273
- Exp Mol Med.
- 2006 Feb;38(1):18-26.
The constrained alpha-helical structure of a C-peptide is useful for enhancing anti-HIV-1 activity. The i and i+3 positions in an alpha-helical structure are located close together, therefore D-Cys (dC) and... -
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- Comparative binding of antitumor drugs to DNA containing the telomere repeat sequence
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Suh D, Oh YK, Ahn BC, Hur MW, Kim HJ, Lee MH, Joo HS, Auh CK
- KMID: 755203
- Exp Mol Med.
- 2002 Nov;34(5):326-331.
Telomeres are the ends of the linear chromosomes of eukaryotes and consist of tandem GT-rich repeats in telomere sequence i.e. 500-3000 repeats of 5'-TTAGGG-3' in human somatic cells, which are... -
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