- Circadian Rhythms in Urinary Functions: Possible Roles of Circadian Clocks?
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Noh JY, Han DH, Yoon JA, Kim MH, Kim SE, Ko IG, Kim KH, Kim CJ, Cho S
- KMID: 2232796
- Int Neurourol J.
- 2011 Jun;15(2):64-73.
Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and... -
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- Mammalian Molecular Clocks
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Kwon I, Choe HK, Son GH, Kim K
- KMID: 2165342
- Exp Neurobiol.
- 2011 Mar;20(1):18-28.
- doi: 10.5607/en.2011.20.1.18
As a consequence of the Earth's rotation, almost all organisms experience day and night cycles within a 24-hr period. To adapt and synchronize biological rhythms to external daily cycles, organisms... -
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- Nocturia: The circadian voiding disorder
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Kim JW, Moon YT, Kim KD
- KMID: 2426490
- Investig Clin Urol.
- 2016 May;57(3):165-173.
- doi: 10.4111/icu.2016.57.3.165
Nocturia is a prevalent condition of waking to void during the night. The concept of nocturia has evolved from being a symptomatic aspect of disease associated with the prostate or... -
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- AMP-activated protein kinase as a key molecular link between metabolism and clockwork
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Lee Y, Kim EK
- KMID: 2154252
- Exp Mol Med.
- 2013 Jul;45(7):e33.
Circadian clocks regulate behavioral, physiological and biochemical processes in a day/night cycle. Circadian oscillators have an essential role in the coordination of physiological processes with the cyclic changes in the... -
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- Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2
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Kim M, de la Peña JB, Cheong JH, Kim HJ
- KMID: 2420386
- Biomol Ther.
- 2018 Jul;26(4):358-367.
- doi: 10.4062/biomolther.2017.131
Most organisms have adapted to a circadian rhythm that follows a roughly 24-hour cycle, which is modulated by both internal (clock-related genes) and external (environment) factors. In such organisms, the... -
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- Anatomy and Physiology in Human Circadian Rhythms
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Sohn CH
- KMID: 2317295
- Sleep Med Psychophysiol.
- 1998 Jun;5(1):1-11.
Chronobiology is the area of medicine that is, how time-related event shape our daily biologic responses and apply to any aspect of medicine with regard to altering pathophysiology and treatment... -
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- Human Circadian Rhythms
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Lee H, Cho CH, Kim L
- KMID: 2317590
- Sleep Med Psychophysiol.
- 2014 Dec;21(2):51-60.
- doi: 10.14401/KASMED.2014.21.2.51
A 'circadian rhythm' is a self-sustained biological rhythm (cycle) that repeats itself approximately every 24 hours. Circadian rhythms are generated by an internal clock, or pacemaker, and persist even in... -
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- Regulation of the Circadian Gene CLOCK Expression by KCl Depolarization in B35 Rat Neuroblastoma Cells
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Jeon WJ, Kim SH, Seo MS, Kang UG, Kim YS, Ahn YM
- KMID: 2341154
- J Korean Neuropsychiatr Assoc.
- 2006 Jan;45(1):21-27.
OBJECTIVES: To investigate the effects of KCl on regulation of circadian gene CLOCK expression, we observed whether induction of CLOCK is influenced by KCl depolarization in B35 rat neuroblastoma cells. METHODS:... -
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- Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice
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Noh JY, Han DH, Kim MH, Ko IG, Kim SE, Park N, Choe HK, Kim KH, Kim K, Kim CJ, Cho S
- KMID: 2155346
- Exp Mol Med.
- 2014 Mar;46(3):e81.
- doi: 10.1038/emm.2013.153
Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and... -
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- Influence of Circadian Disruption Associated With Artificial Light at Night on Micturition Patterns in Shift Workers
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Kim SJ, Kim JW, Cho YS, Chung KJ, Yoon H, Kim KH
- KMID: 2468711
- Int Neurourol J.
- 2019 Dec;23(4):258-264.
- doi: 10.5213/inj.1938236.118
Shift workers often experience problems associated with circadian disruption associated with artificial light at night and nocturia is commonly noted in night-shift workers. Nocturia associated with circadian disruption is due... -
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- Circadian Regulation by REV-ERBα Mediates Hippocampal E-LTP in a Time-dependent Manner
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Choi JE, Kim S, Lee J, Kim K, Kaang BK
- KMID: 2424729
- Exp Neurobiol.
- 2018 Oct;27(5):344-349.
- doi: 10.5607/en.2018.27.5.344
Circadian rhythms are driven by circadian oscillators, and these rhythms result in the biological phenomenon of 24-h oscillations. Previous studies suggest that learning and memory are affected by circadian rhythms.... -
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- The Effect of Sleep Disturbances and Melatonin in Inflammatory Bowel Disease
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Park YS
- KMID: 2233113
- Intest Res.
- 2011 Aug;9(2):85-89.
- doi: 10.5217/ir.2011.9.2.85
Inflammatory bowel disease (IBD) is an idiopathic condition which increases and decreases in intensity and results in a poor quality of life for those afflicted. Advances in the molecular machinery... -
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- High-fat Intake is Associated with Alteration of Peripheral Circadian Clock Gene Expression
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Park HK, Park JY, Lee H
- KMID: 2361646
- J Korean Biol Nurs Sci.
- 2016 Nov;18(4):305-317.
- doi: 10.7586/jkbns.2016.18.4.305
PURPOSE: Recent studies demonstrated disruption of the circadian clock gene is associated with the development of obesity and metabolic syndrome. Obesity is often caused by the high calorie intake, In... -
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- A study on the expression of immediate-early genes by light stimuli in the rat suprachiasmatic nucleus using differential display
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Park HT, Kim WI, Kang EK, Park JK, Bae KW
- KMID: 2040090
- Korean J Anat.
- 1999 Aug;32(4):451-457.
The hypothalamic suprachiasmatic nucleus (SCN) of the mammal is the circadian pacemaker responsible for generation of circadian rhythms. Several immediate-early genes are expressed in the SCN by light stimuli which... -
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- A Role for Timely Nuclear Translocation of Clock Repressor Proteins in Setting Circadian Clock Speed
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Lee E, Kim EY
- KMID: 2165522
- Exp Neurobiol.
- 2014 Sep;23(3):191-199.
- doi: 10.5607/en.2014.23.3.191
By means of a circadian clock system, all the living organisms on earth including human beings can anticipate the environmental rhythmic changes such as light/dark and warm/cold periods in a... -
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- Differential gene expression analysis of human cumulus cells
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Demiray SB, Goker EN, Tavmergen , Yilmaz O, Calimlioglu N, Soykam HO, Oktem G, Sezerman U
- KMID: 2452646
- Clin Exp Reprod Med.
- 2019 Jun;46(2):76-86.
- doi: 10.5653/cerm.2019.46.2.76
OBJECTIVE: This study was performed to explore the possibility that each oocyte and its surrounding cumulus cells might have different genetic expression patterns that could affect human reproduction. METHODS: Differential gene... -
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- Effect of Resveratrol, a SIRT1 Activator, on the Interactions of the CLOCK/BMAL1 Complex
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Park I, Lee Y, Kim HD, Kim K
- KMID: 2169476
- Endocrinol Metab.
- 2014 Sep;29(3):379-387.
- doi: 10.3803/EnM.2014.29.3.379
BACKGROUND: In mammals, the CLOCK/BMAL1 heterodimer is a key transcription factor complex that drives the cyclic expression of clock-controlled genes involved in various physiological functions and behavioral consequences. Recently, a... -
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- Jet Lag and Circadian Rhythms
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Kim L
- KMID: 2317279
- Sleep Med Psychophysiol.
- 1997 Jun;4(1):57-65.
As jet lag of modern travel continues to spread, there has been an exponential growth in popular explanations of jet lag and recommendations for curing it. Some of this attention... -
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- Neuroanatomy of Sleep-Wake Regulation and its Application to Pharmacotherapy
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Kim HC
- KMID: 2286720
- Korean J Psychopharmacol.
- 2007 May;18(3):133-142.
A current hypothesis of sleep-wake regulation proposes that the sleep process starts with the activation of sleep-promoting neurons located in the preoptic area of the anterior hypothalamus. This activation leads... -
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- Human Physiological Models of Insomnia
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Sim HB, Yu BH
- KMID: 2317467
- Sleep Med Psychophysiol.
- 2009 Jun;16(1):5-9.
Relatively little is known about the neurobiology of insomnia, despite its wide prevalence and broad medical impact. Although much is still to be learned about the pathophysiology of the disorder,... -
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