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The Role of Oxidative Stress in the Pathogenesis of Diabetic Vascular Complications

Sasaki S, Inoguchi T

Oxidative stress has been paid increasing attention to as an important causative factor for diabetic vascular complications. Among possible various sources, accumulating evidence has indicated that NAD(P)H oxidase may be...
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Role of Mast Cells in Allergic Inflammation and Innate Immunity

Ahn K

  • KMID: 1655406
  • Korean J Pediatr.
  • 2004 Nov;47(11):1137-1141.
Mast cells play a key role in elicitation of the early-phase and late-phase IgE-mediated allergic inflammatory reactions. Mast cells are derived from pluripotent stem cells from the bone marrow. These...
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The Influence of IgE on Cultured Human Mast Cells

Frandsen P, Krohn IJ, Hoffmann H, Schiotz PO

PURPOSE: The mast cell plays a pivotal role in the human immune response. Crosslinking of 2 IgE molecules bound to the high affinity IgE receptor (FcepsilonRI) on the surface of...
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Mast Cells in 10-Dimethyl-1,2 Benzanthracene (DMBA)-Induced Rat Mammary Carcinomas: Relationship with Matrix Metallproteinase (MMP)-2 and MMP-9 Expression

Lee HH, Kim AR, Yeom BW, Kim I

  • KMID: 1725818
  • Korean J Pathol.
  • 2001 Aug;35(4):306-313.
BACKGROUND: It has been suggested that mast cells are involved in the tumor growth and progression by production of a variety of enzymes and growth factors. They were studied in...
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Association of the Polymorphisms in the PSMA6 (rs1048990) and PSMB5 (rs2230087) Genes with Type 2 Diabetes in Korean Subjects

Kim HK, Kim SW, Doh YJ, Kim SR, Kim MK, Park KG, Kim HS, Park KS, Yoo M, Kim JG, Kim BW, Lee IK

BACKGROUND: The 26S ubiquitin-proteasome system (UPS) is a principal proteolytic pathway of intracellular molecules regulating apoptosis, cell cycle, cell proliferation or differentiation, inflammation and etc. The recent study suggests that...
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Mucosal mast cell-derived chondroitin sulphate levels in and worm expulsion from FcRgamma-knockout mice following oral challenge with Strongyloides venezuelensis

Onah DN, Nawa Y

  • KMID: 1099835
  • J Vet Sci.
  • 2004 Sep;5(3):221-226.
Mucosal mast cell-derived chondroitin sulphates (sulphated proteoglycans) were assayed in gut washings and homogenate of FcRgamma-knockout (KO) and wild-type (WT) C57BL/6 mice challenged with Strongyloides venezuelensis in order to assess...
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