- Reconstitution of class I MHC molecules expressed in E. coli and complexed with single antigenic peptides
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Kim J, Kim MY, Chwae YJ, Park JH
- KMID: 1081047
- J Korean Med Sci.
- 1997 Aug;12(4):280-285.
- doi: 10.3346/jkms.1997.12.4.280
The HLA-Cw3 heavy chain has been expressed at high level as insoluble protein aggregates in E. coli. The protein aggregates dissolved in strong denaturant solution were efficiently reconstituted by... -
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- Association of Killer Cell Ig-like Receptor (KIR) with an Adaptor Protein Shc
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Cho HI, Chwae YJ, Park SM, Kim J
- KMID: 2150616
- Immune Netw.
- 2006 Jun;6(2):67-75.
- doi: 10.4110/in.2006.6.2.67
BACKGROUND: Cytotoxic function of killer cells is inhibited by specific recognition of class I MHC molecules on target cells by inhibitory killer Ig-like receptors (KIR) expressed on NK cells and... -
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- Identification of the CDR3 Gene Sequence on the beta Chain of the T Cell Receptor in T Cell Leukemia Cell Line
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Choi IH, Kim SJ, Kim JD, Chwae YJ
- KMID: 1548379
- Korean J Immunol.
- 1997 Dec;19(4):541-548.
In order to develop a method for the detection of minimal residual leukemic disease (MRD) in T cell acute lymphocytic leukemia (T cell ALL), T cell leukemia cell line was... -
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- Phosphatidylinositol 4-phosphate 5-kinase alpha is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses
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Lee SY, Kim B, Yoon S, Kim YJ, Liu T, Woo JH, Chwae YJ, Joe EH, Jou I
- KMID: 983958
- Exp Mol Med.
- 2010 Sep;42(9):662-673.
- doi: 10.3858/emm.2010.42.9.066
In brain tissue, astrocytes play defensive roles in central nervous system integrity by mediating immune responses against pathological conditions. Type I phosphatidylinositol 4-phosphate 5-kinase alpha (PIP5Kalpha) that is responsible for... -
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- Radiation-Induced Autophagy Contributes to Cell Death and Induces Apoptosis Partly in Malignant Glioma Cells
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Jo GH, Bogler O, Chwae YJ, Yoo H, Lee SH, Park JB, Kim YJ, Kim JH, Gwak HS
- KMID: 2132801
- Cancer Res Treat.
- 2015 Apr;47(2):221-241.
- doi: 10.4143/crt.2013.159
PURPOSE: Radiation-induced autophagy has been shown to play two different roles, in malignant glioma (MG) cells, cytocidal or cytoprotective. However, neither the role of radiation-induced autophagy for cell death nor... -
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- B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1
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Choi YW, Kim HJ, Kim YH, Park SH, Chwae YJ, Lee J, Soh EY, Kim JH, Park TJ
- KMID: 2155385
- Exp Mol Med.
- 2014 Nov;46(11):e120.
- doi: 10.1038/emm.2014.68
B-RafV600E mutant is found in 40-70% of papillary thyroid carcinoma (PTC) and has an important role in the pathogenesis of PTC. The sodium iodide symporter (NIS) is an integral plasma... -
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- The role of autophagy in allergic inflammation: a new target for severe asthma
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Liu JN, Suh DH, Trinh HK, Chwae YJ, Park HS, Shin YS
- KMID: 2361530
- Exp Mol Med.
- 2016 Jul;48(7):e243.
- doi: 10.1038/emm.2016.38
Autophagy has been investigated for its involvement in inflammatory diseases, but its role in asthma has been little studied. This study aimed to explore the possible role of autophagy and... -
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