- Loss of heterozygosity on chromosome 10, 13q(Rb), 17p, and p53 gene mutations in human brain gliomas
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Lee SH, Kim JH, Rhee CH, Kang YS, Lee JH, Hong SI, Choi KS
- KMID: 927177
- J Korean Med Sci.
- 1995 Dec;10(6):442-448.
- doi: 10.3346/jkms.1995.10.6.442
Using the methods of restriction fragment length polymorphism (RFLP) and single strand conformation polymorphism (SSCP) analyses, we have examined 33 cases of human gliomas with various malignant grades to detect... -
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- Molecular genetic study of primary malignant brain tumors:loss of heterozygosity on chromosome 10, 13q, 17q and 22q
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Lee SH, Kim JH, Lee CH, Kang YS, Lee JH
- KMID: 1694371
- J Korean Cancer Assoc.
- 1993 Oct;25(5):717-724.
No abstract available. -
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- A case of terminal deletion of chromosome 10p
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Cho JH, Park JE, Ko MK, Kim EJ, Park JK, Lee SA, Lee JH, Paik WY
- KMID: 2274055
- Korean J Obstet Gynecol.
- 2011 Jul;54(7):386-389.
- doi: 10.5468/KJOG.2011.54.7.386
Chromosome 10p deletion (partial monosomy 10p) is rare chromosomal disorder. It was first reported in 1970. Since then, as far as we know, about 45 patients have been described. The... -
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- Clathrin Assembly Lymphoid Myeloid Leukemia-AF10-positive Acute Leukemias: A Report of 2 Cases with a Review of the Literature
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Huh JY, Chung S, Oh D, Kang MS, Eom HS, Cho EH, Han MH, Kong SY
- KMID: 1096795
- Korean J Lab Med.
- 2010 Apr;30(2):117-121.
- doi: 10.3343/kjlm.2010.30.2.117
The translocation t(10;11)(p13;q14q21) has been found to be recurrent in acute lymphoblastic and myeloid leukemias, and results in the fusion of the clathrin assembly lymphoid myeloid leukemia (CALM) gene with... -
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- A Case of Partial Monosomy lOq Syndrome
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Kim YK, Park YW, Lee CG, Kim SW
- KMID: 2041991
- J Korean Pediatr Soc.
- 1999 Jun;42(6):863-867.
It has been estimated that chromosomal aberrations account for 2.3% to 3% of normal pregnancies and of them 85% are aborted. Therefore, the survival rate of neonates with chromosomal aberrations... -
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- Loss of Heterozygosity on Chromosome 10, 13, 17 and p53 Gene Mutations in Human Brain Gliomas
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Lee SH, Kim JH, Rhee CH, Kang YS, Lee JH, Choi KS
- KMID: 2187842
- J Korean Neurosurg Soc.
- 1993 Apr;22(4):537-550.
Gliomas, the most common primary tumors of the human central nervous system, are usually malignant and virtually incurable. They can be classified according to their cellular differentiation:astrocytoma, oligodendroglioma, and ependymoma.... -
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- A Case of Trisomy 10p with Vertebral Anomaly and Hypospadias
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Kim HS, Baek SC, Kim CH
- KMID: 1838163
- Korean J Perinatol.
- 2003 Dec;14(4):427-432.
Tisomy 10p syndrome is a rarely reported chromosomal abnormality with distinct craniofacial anomalies, severe growth and psychomotor retardation, osteoarticular anomalies, and organ malformations. Most of reported cases were due to... -
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- Multiorgan Involvements of Cowden Disease in a 50-Year-Old Woman: A Case Report and Literature Overview
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Lee EJ, Jung WS, Ko JM, Park HJ
- KMID: 2208809
- J Korean Soc Radiol.
- 2013 Sep;69(3):251-255.
- doi: 10.3348/jksr.2013.69.3.251
Cowden disease is the prototype of phosphate and, tensin homologue deleted on the chromosome 10 (PTEN) hamartoma tumor syndrome caused by germline mutations in the tumor suppressor PTEN, which is... -
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- Synchronous Bilateral Breast Carcinoma in a Patient with Cowden Syndrome with PTEN Mutation: A Case Report
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Kwon SY, Yeo SH, Ha JS, Kang SH
- KMID: 2434908
- J Breast Dis.
- 2018 Dec;6(2):79-83.
- doi: 10.14449/jbd.2018.6.2.79
Cowden syndrome (CS), also known as multiple hamartomas syndrome, is a rare hereditary autosomal dominant disorder caused by a germline mutation in the phosphatase and tensin homolog (PTEN) gene mapped... -
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- Mapping of the Faded (fe) Gene to a Region between D10mit191 and D10mit44 on Mouse Chromosome 10
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Oh SH, Nam Y, Suh JG
- KMID: 2391857
- Lab Anim Res.
- 2011 Mar;27(1):41-46.
- doi: 10.5625/lar.2011.27.1.41
The faded mouse is a coat color mutant that shows faded coat color and age-related loss of pigmentation. This mutation is transmitted by an autosomal recessive gene with 100% penetrance.... -
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- Over-expression of PTEN Involved in Troglitazone-induced Apoptosis in Human Osteosarcoma Cells
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Yoon SJ, Zhou L, Kim JR
- KMID: 2137040
- J Korean Bone Joint Tumor Soc.
- 2011 Jun;17(1):23-29.
- doi: 10.5292/jkbjts.2011.17.1.23
PURPOSE: We investigated the effects of phosphatase and tensin homologue deleted on chromosome 10 gene phosphatase and tensin homologue deleted on chromosome 10 gene (PTEN) expression on the cell proliferation... -
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- A high resolution genetic mapping of the faded (fe) gene to a region between D10mit156 and D10mit193 on mouse chromosome 10
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Oh SH, Nam H, Suh JG
- KMID: 2312101
- Lab Anim Res.
- 2013 Mar;29(1):33-38.
- doi: 10.5625/lar.2013.29.1.33
The C57BL/6J-fe/fe mouse is a coat color mutant. The coat color of the homozygote mouse becomes progressively lighter with advancing age. The faded gene (fe) of C57BL/6J-fe/fe was mapped in... -
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- Two Cases of Multiple Endocrine Neoplasia Type II with RET Mutaion
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Yoo SY, Choi YH, Lee MK, Kim MS, Hwang PH
- KMID: 2279829
- Clin Pediatr Hematol Oncol.
- 2014 Oct;21(2):163-167.
- doi: 10.0000/cpho.2014.21.2.163
Multiple endocrine neoplasia type 2(MEN2) is a rare autosomal dominant inherited disorder characterized by the presence of medullary thyroid carcinoma, pheochromocytoma and other hyperplasia and/or neoplasia of different endocrine tissues... -
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- Loss of PTEN Expression in Primary Lung Cancer
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Roh MS
- KMID: 2275559
- Korean J Pathol.
- 2002 Oct;36(5):286-291.
BACKGROUND: The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) gene, a candidate tumor suppressor, is localized to chromosome 10q23 and shares extensive homology with cytoskeletal proteins auxilin and... -
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- PTEN expression and single nucleotide polymorphisms in epithelial tumors of the ovary
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Hwang JS, Park IS, Lee YS
- KMID: 2244534
- Korean J Gynecol Oncol.
- 2007 Dec;18(4):308-317.
OBJECTIVE: Phosphate and tensin homolog deleted on chromosome 10 (PTEN) is a potent tumor suppressor gene, localized to chromosome 10q23, and shows extensive homology with auxilin and tension. PTEN has... -
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- A Case of Papillary Thyroid Carcinoma Combined with Multiple Endocrine Neoplasia Type 2A
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Kim JK, Chung HW, Seo HS, Kim DJ, Chung SS, Song YD, Kwon KH, Jin YM, Lee MK, Lim SK, Kim IJ, Kang HC, Park JH, Park JG
- KMID: 2200061
- J Korean Soc Endocrinol.
- 2002 Oct;17(5):730-738.
Multiple endocrine neoplasia (MEN) type 2A is a syndrome of medullary thyroid carcinomas, pheochromocytomas and parathyroid hyperplasia. The simultaneous occurrence of medullary, and papillary, thyroid carcinomas is rare because they... -
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- An unusual de novo duplication 10p/deletion 10q syndrome: The first case in Korea
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Lee BY, Park JY, Lee YW, Oh AR, Lee SY, Choi EY, Kim MY, Ryu HM, Park SY
- KMID: 2055590
- J Genet Med.
- 2015 Jun;12(1):49-56.
- doi: 10.5734/JGM.2015.12.1.49
We herein report an analysis of a female baby with a de novo dup(10p)/del(10q) chromosomal aberration. A prenatal cytogenetic analysis was performed owing to abnormal ultrasound findings including a choroid... -
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- Polymorphism of Codon 54 and Promoter of Mannose-binding Lectin Gene in Korean Atopic Dermatitis Patients
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- KMID: 2299777
- Korean J Asthma Allergy Clin Immunol.
- 2005 Mar;25(1):16-22.
BACKGROUND: Atopic dermatitis (AD) is an IgE mediated hypersensitivity reaction, generally considered to be caused by interaction of genetic and environmental factors. Human mannose-binding lectin (MBL) belongs to a group... -
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- MiR-182-5p Knockdown Targeting PTEN Inhibits Cell Proliferation and Invasion of Breast Cancer Cells
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Zhao YS, Yang WC, Xin HW, Han JX, Ma SG
- KMID: 2431631
- Yonsei Med J.
- 2019 Feb;60(2):148-157.
- doi: 10.3349/ymj.2019.60.2.148
PURPOSE: Breast cancer (BC) is one of the most common malignant tumors, affecting a significant number of women worldwide. MicroRNAs (miRNAs) have been reported to play important roles in tumorigenesis.... -
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- Expression of RET in Thyroid Diseases of a Korean Population
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Lee SH, Hong SW, Moon WC, Oh MR, Lee JK, Cha BS, Ahn CW, Kim KR, Lim SK, Lee HC
- KMID: 2331170
- J Korean Soc Endocrinol.
- 2003 Apr;18(2):140-152.
BACKGROUND: Activation of the RET proto-oncogene, located on the long arms of chromosome 10, contributes to the development of thyroid cancers in two different ways. Somatic rearrangements of RET with... -
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