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Mycophenolate Mofetil Overdose Induced Ventricular Tachycardia in a Patient with Systemic Lupus Erythematosus

Kim JH, Chung H, Lee KA, Kim HR, Lee SH

Mycophenolate mofetil (MMF) is an immunosuppressive agent used to treat severe lupus, including lupus nephritis. Common adverse effects of MMF include gastrointestinal and hematological manifestations; however, cardiac toxicity in association...
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A Case of Methimazole-Resistant Severe Graves' Disease: Dramatic Response to Cholestyramine

Chae SB, Kim ES, Lee YI, Min BR

A 22-year-old woman with severe Graves' disease was referred from a local clinic because of her refractory hyperthyroidism. She presented with exophthalmos, diffuse goiter, and tachycardia. She was treated with...
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Cholestyramine Use for Rapid Reversion to Euthyroid States in Patients with Thyrotoxicosis

Ha J, Jo K, Kang B, Kim MH, Lim DJ

Cholestyramine (CS) is an ion exchange resin, which binds to iodothyronines and would lower serum thyroid hormone level. The use of CS added to conventional antithyroid drugs to control thyrotoxicosis...
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Refractory Graves' Disease Successfully Cured by Adjunctive Cholestyramine and Subsequent Total Thyroidectomy

Yang Y, Hwang S, Kim M, Lim Y, Kim MH, Lee S, Lim DJ, Kang MI, Cha BY

The three major forms of treatment for Graves thyrotoxicosis are antithyroid drugs, radioactive iodine therapy and thyroidectomy. Surgery is the definitive treatment for Graves thyrotoxicosis that is generally recommended when...
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Pharmacologic Agents for Chronic Diarrhea

Lee KJ

Chronic diarrhea is usually associated with a number of non-infectious causes. When definitive treatment is unavailable, symptomatic drug therapy is indicated. Pharmacologic agents for chronic diarrhea include loperamide, 5-hydroxytryptamine type...
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Leflunomide-induced Toxic Epidermal Necrolysis in a Patient with Rheumatoid Arthritis

Je JH, Lee HJ, Na YJ, Seo JH, Seo YH, Kim JH, Choi SJ, Lee YH, Ji JD, Song GG

Leflunomide was licensed for the treatment of rheumatoid arthritis in 1998 and has been available in Korea since 2003. Allergic cutaneous reactions (rash, purpura) are common (
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Diagnosis and Management of Chronic Diarrhea

Choi MG

  • KMID: 2263403
  • Korean J Med.
  • 2012 Nov;83(5):585-590.
Diarrhea is exceedingly common and produces high economic burden. Understanding pathophysiologic mechanisms of chronic diarrhea facilitates a rational approach to diagnosis and management. Careful history taking and physical examination can...
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Cholestyramine resin for erythropoietic protoporphyria with severe hepatic disease: a case report

Yoo DJ, Lee HC, Yu E, Jin YJ, Shim JH, Kim KM, Lim YS, Chung YH, Lee YS, Suh DJ

Erythropoietic protoporphyria (EPP) is a rare disorder of heme biosynthesis caused by mutations in the gene encoding the enzyme ferrochelatase. In EPP, deficient ferrochelatase activity leads to the excessive production...
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A Case of Interstitial Pneumonitis in a Patient with Rheumatoid Arthritis Treated with Leflunomide

Shin AY, Kim SS, Kim KH, Ju IN, Ko HJ

  • KMID: 2319182
  • Tuberc Respir Dis.
  • 2009 Jun;66(6):477-481.
Leflunomide, a disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis has been available in Korea since 2003. Leflunomide-associated interstitial pneumonitis has been appearing recently. A 25-year-old woman with...
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Successful Treatment of Interstitial Pneumonitis Induced by Leflunomide

Sheen DH, Lim MK, Shim SC, Lee SO, Kang SW, Song JK, Lee YS

Leflunomide is a disease-modifying antirheumatic drug that has been available in Korea since 2003. Leflunomide induced interstitial pneumonitis has been reported as an adverse effect in other countries but not...
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Effect of Oral Administration of Dioctahedral Smectite and Cholestyramine with Phototherapy in the Treatment of Neonatal Hyperbilirubinemia

Kwon JB, Oh MH, Sim JG, Kim MH

  • KMID: 2099015
  • J Korean Soc Neonatol.
  • 2000 May;7(1):39-44.
PURPOSE: Dioctahedral smectite is an alumina silicate of phyllitic structure and absorbs bile acid in the intestine, forming a non-absorbable complex preventing enterohepatic circulation. The purpose of this study is...
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A Clinical Investigation of Clostridium difficile-Associated Disease

Lee CR, Lee JK, Cho YS, Yoo HM, Kim WH, Lee KW

  • KMID: 2084899
  • Korean J Gastroenterol.
  • 1999 Mar;33(3):338-347.
BACKGROUND/AIMS: Clostridium difficile-associated disease (CDAD) is a common cause of anti biotics-associated diarrhea. The purpose of this study is to understand the clinical, microbiological endoscopic and pathological features of CDAD....
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4 Cases of Pseudomembranous Colitis Confirmed by Clostridium Culture

Lee NM, Won JH, Lee MS, Kim JH, Cho SW, Shim CS

  • KMID: 1928914
  • Korean J Gastrointest Endosc.
  • 1989 Nov;9(2):221-226.
Diarrhea is a common complication of antibiotics usage. The diarrhea ascribed to antibiotics usually consist of loose or watery stools, sometimes containing mucus but rarely grossly evident blood. Almost every...
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A Clinical Study on Pseudomembranous Colitis

Lim PS, Yun HD, Yim KW, Song IS, Choi KW, Kim CY

  • KMID: 2243885
  • Korean J Gastrointest Endosc.
  • 1987 Nov;7(1):13-17.
The purpose of this study is to review the clinical and pathological features of pseudomembranous colitis in Korea. Ten cases of psedomembranous colitis, which were diagnosed by sigmoidoscopy and biopsy...
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