- Frequency of Loss of Heterozygosity on Chromosome 17 in Intrahepatic Cholangiocarcinoma
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Kim HJ, Kang CD, Lee SJ, Cho SJ, Kim JS
- KMID: 782762
- Korean J Gastroenterol.
- 2006 Sep;48(3):188-194.
BACKGROUND/AIMS: Intrahepatic cholangiocarcinoma is the second most common intrahepatic neoplasm. Carcinogenesis is believed to be a multistage process that occurs as a result of mutations in oncogenes and tumor suppressor... -
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- Genetic Alterations in Intrahepatic Cholangiocarcinoma as revealed by Degenerate Oligonucleotide Primed PCR-Comparative Genomic Hybridization
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Lee JY, Park YN, Uhm KO, Park SY, Park SH
- KMID: 1733509
- J Korean Med Sci.
- 2004 Oct;19(5):682-687.
- doi: 10.3346/jkms.2004.19.5.682
Intrahepatic cholangiocarcinoma (ICC), a malignant neoplasm of the biliary epithelium, is usually fatal because of difficulty in early diagnosis and lack of availability of effective therapy. The genetic mechanisms involved... -
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- Genetic and expression alterations in association with the sarcomatous change of cholangiocarcinoma cells
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Yoo HJ, Yun BR, Kwon JH, Ahn HS, Seol MA, Lee MJ, Yu GR, Yu HC, Hong B, Choi K, Kim DG
- KMID: 1109433
- Exp Mol Med.
- 2009 Feb;41(2):102-115.
- doi: 10.3858/emm.2009.41.2.013
Cholangiocarcinoma (CC) is an intrahepatic bile duct carcinoma with a high mortality rate and a poor prognosis. Sarcomatous change/epithelial mesenchymal transition (EMT) of CC frequently leads to aggressive intrahepatic spread... -
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