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Interferon-gamma upregulates the stromelysin-1 gene expression by human skin fibroblasts in culture

Lee KS, Ryoo YW, Song JY

  • KMID: 754989
  • Exp Mol Med.
  • 1998 Jun;30(2):59-64.
The equilibrium between deposition and degradation of extracellular matrix(ECM) is essential to normal tissue development and repair of wound or inflammatory responses. It has recently become apparent that several cytokines and growth factors...
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Transcriptional activation of insulin-like growth factor binding protein 6 by 17beta-estradiol in SaOS-2 cells

Zhao YY, Guo L, Zhao XJ, Liu H, Lei T, Ma DJ, Gao XY

Osteoblasts can synthesize the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs), which may either enhance or attenuate IGF-stimulated bone cell proliferation. Since estrogen induced osteoblastic differentiation and proliferation...
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Cloning and characterization of 5'-upstream region of human phospholipase C-beta2 gene

Yun ES, Lee SJ, Kim MJ, Ryu SH, Suh PG

  • KMID: 1085743
  • Exp Mol Med.
  • 2001 Jun;33(2):76-82.
5'-upstream region of the phospholipase C-beta2 gene, 810 bp, was cloned and characterized. S1 nuclease mapping and primer extension analyses revealed that a single transcriptional start site locates at 284...
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