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Doxorubicin Promotes Migration and Invasion of Breast Cancer Cells through the Upregulation of the RhoA/MLC Pathway

Liu CL, Chen MJ, Lin JC, Lin CH, Huang WC, Cheng SP, Chen SN, Chang YC

PURPOSE: Cancer cells develop acquired resistance induced by chemotherapeutic drugs. In this study, we investigated the effects of brief treatment with cytotoxic drugs on the phenotype of breast cancer cells. METHODS:...
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The Evaluation of Otilonium Bromide Treatment in Asian Patients With Irritable Bowel Syndrome

Chang FY, Lu CL, Luo JC, Chen TS, Chen MJ, Chang HJ

  • KMID: 2325842
  • J Neurogastroenterol Motil.
  • 2011 Oct;17(4):402-410.
BACKGROUND/AIMS: Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to...
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The Feasibility of Using Simulated Targets in the Stomachs of Live Pigs for Full Endoscopic Submucosal Dissection Training

Wang HY, Shih SC, Hung CY, Liu CY, Shieh TY, Chen MJ

BACKGROUND/AIMS: In endoscopic submucosal dissection (ESD) training, only a flat target lesion can usually be simulated in the normal mucosa. This study aimed to evaluate the feasibility of simulated targets...
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