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A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells

Jang J, Yoon Y, Oh DJ

BACKGROUND: Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif and is produced by endothelial cells stimulated with lipopolysaccharide (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon-γ. There...
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Tissue-specific Role of CX₃CL1 Expressing Immune Cells and Their Relationships with Human Disease

Lee M, Lee Y, Song J, Lee J, Chang SY

Chemokine (C-X3-C motif) ligand 1 (CX₃CL1, also known as fractalkine) and its receptor chemokine (C-X3-C motif) receptor 1 (CX₃CR1) are widely expressed in immune cells and non-immune cells throughout organisms....
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Investigation of the Expression of Fractalkine and the Infiltration Characteristics of Fractalkine Receptor Positive Cells and Macrophages in Cisplatin-induced Acute Renal Failure in Mice

Kim TY, Jin NW, Kim SM, Lee KE, Ahn J, Kim SH, Oh DJ, Yu SH

  • KMID: 1477207
  • Korean J Nephrol.
  • 2008 Nov;27(6):642-649.
PURPOSE: The aim of the present study was to investigate the expression and the infiltration characteristics of fractalkine (CX3CL1)/ its receptor (CX3CR1) positive cells and macrophages in cisplatininduced ARF (CisARF). METHODS:...
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Alpha-Lipoic acid Inhibits TNF-alpha-Induced Fractalkine Expression in Rat aortic Smooth Muscle Cells

Park KG, Kim HS, Ryu SY, Nam CW, Chae BK, Jung ED, Kim JG, Kim BW, Lee IK

  • KMID: 2008233
  • J Korean Diabetes Assoc.
  • 2005 Sep;29(5):409-417.
BACKGOUND: The induction of vascular inflammation via the proinflammatory cytokine/ nuclear factor (NF)-kappaB pathway is one of the key mechanisms in the development and progression of atherosclerosis. Accumulating evidence suggests...
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Ascochlorin Derivative, AS-6, Inhibits TNF-alpha-Induced fractalkine, MCP-1 and VCAM-1 Expression in Rat Aortic Smooth Muscle Cells

Jang YY, Kim SY, Kim NK, Kim MK, Kim HK, Kim HS, Nam CW, Ryu SY, Nam SI, Park KG

  • KMID: 2008232
  • J Korean Diabetes Assoc.
  • 2005 Sep;29(5):401-408.
BACKGOUND: Inflammation is one of the key mechanisms in the development and progression of atherosclerosis. Accumulating evidence suggests that peroxisome proliferators- activated receptorgamma(PPARgamma) plays an important role in the prevention...
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Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome

Rodríguez-Fandiño OA, Hernández-Ruiz J, López-Vidal Y, Charúa-Guindic L, Escobedo G, Schmulson

  • KMID: 2433529
  • J Neurogastroenterol Motil.
  • 2017 Apr;23(2):281-288.
  • doi: 10.5056/jnm16137
BACKGROUND/AIMS: Abnormal immune regulation and increased intestinal permeability augmenting the passage of bacterial molecules that can activate immune cells, such as monocytes/macrophages, have been reported in irritable bowel syndrome (IBS)....
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