- Anti-cancer Effect of Luminacin, a Marine Microbial Extract, in Head and Neck Squamous Cell Carcinoma Progression via Autophagic Cell Death
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Shin YS, Cha HY, Lee BS, Kang SU, Hwang HS, Kwon HC, Kim CH, Choi EC
- KMID: 2454352
- Cancer Res Treat.
- 2016 Apr;48(2):738-752.
- doi: 10.4143/crt.2015.102
PURPOSE: The purpose of this study is to determine whether luminacin, a marine microbial extract from the Streptomyces species, has anti-tumor effects on head and neck squamous cell carcinoma (HNSCC)... -
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- Activation of epidermal growth factor receptor is responsible for pervanadate-induced phospholipase D activation
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Kim YR, Cha HY, Lim K, Hwang BD, Hoe KL, Namgung U, Park SK
- KMID: 1097260
- Exp Mol Med.
- 2003 Apr;35(2):118-124.
Pervanadate, a complex of vanadate and H2O2, has an insulin mimetic effect, and acts as an inhibitor of protein tyrosine phosphatase. Pervanadate-induced phospholipase D (PLD) activation is known to be... -
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- Diabetes and Alzheimer's Disease: Mechanisms and Nutritional Aspects
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Lee HJ, Seo HI, Cha HY, Yang YJ, Kwon SH, Yang SJ
- KMID: 2424298
- Clin Nutr Res.
- 2018 Oct;7(4):229-240.
- doi: 10.7762/cnr.2018.7.4.229
Blood glucose homeostasis is well maintained by coordinated control of various hormones including insulin and glucagon as well as cytokines under normal conditions. However, chronic exposure to diabetic environment with... -
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- Clonal Types and Antimicrobial Susceptibilitiy Patterns in Methicillin-Resistant Staphylococcus aureus Isolates from a Korean Hospital
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Cha HY, Cho DT, Nho SO, Her SH, Lee YC, Seol SY, Chang HH, Kim SW, Lee JC
- KMID: 2168479
- J Bacteriol Virol.
- 2005 Mar;35(1):31-37.
A total of 54 non-duplicate methicillin-resistant Staphylococcus aureus (MRSA) isolates from clinical specimens and 3 MRSA isolates from healthy medical staffs were obtained from Kyungpook National University Hospital. They were... -
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- Epigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion
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Kwak IH, Shin YH, Kim M, Cha HY, Nam HJ, Lee BS, Chaudhary , Pai KS, Lee JH
- KMID: 1097268
- Exp Mol Med.
- 2011 Feb;43(2):111-120.
- doi: 10.3858/emm.2011.43.2.013
Aberrant activation of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor, Met, is involved in the development and progression of many human cancers. In the cell-based screening assay, (-)epigallocatechin-3-gallate (EGCG)... -
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- Therapeutic effect of hepatocyte growth factor-secreting mesenchymal stem cells in a rat model of liver fibrosis
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Kim MD, Kim SS, Cha HY, Jang SH, Chang DY, Kim W, Suh-Kim H, Lee JH
- KMID: 2155375
- Exp Mol Med.
- 2014 Aug;46(8):e110.
- doi: 10.1038/emm.2014.49
Bone marrow-derived mesenchymal stromal cells (MSCs) have been reported to be beneficial for the treatment of liver fibrosis. Here, we investigated the use of genetically engineered MSCs that overexpress hepatocyte... -
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