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New Functions for Telomerase

Hahn WC

  • KMID: 1972865
  • Cancer Res Treat.
  • 2003 Dec;35(6):467-471.
Telomeres are nucleoprotein structures that compose the ends of eukaryotic chromosomes and that regulate chromosome integrity and cell proliferative lifespan. Stabilization of telomere length correlates with cell immortalization, and constitutive...
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Effect of High Concentration of Estradiol on Thyroid Specific Genes Expression and Cell Growth

Kim DW, Park HY, Kim DH, Kim HJ, Chung HK

BACKGROUND: Since various thyroid diseases have dominant prevalence in women, it has been suggested that female sex hormone have important role on thyroid cell physiology. Interestingly, many thyroid disorders are...
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Expression of Mouse Homolog of Glucosamine-6-Phosphate Deaminase in Reproductive Organs

Gye MC, Kim CG, Ahn HS, Kim YS

  • KMID: 1859348
  • Korean J Androl.
  • 2000 Apr;18(1):41-46.
PURPOSE: To verify the expression of the mouse homolog of glucosamine-6-phosphate deaminase (GNPDA) in the testis and reproductive organs. MATERIALS AND METHODS: Expression of GNPDA was examined using a polyclonal antibody...
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Development of Tetracycline-regulated Adenovirus Expression Vector System

Son KH, Lee SH, Kim JS, Choi JJ, Lee JH

  • KMID: 1536942
  • J Genet Med.
  • 1999 Dec;3(1):33-36.
Recombinant adenovirus vector systems with strong promoters have been used to achieve high level production of recombinant protein. However, this overexpression system cause some problems such as disturbance of cell...
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Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma

Liu Y, Jia L, Liu ZC, Zhang H, Zhang PJ, Wan Q, Wang R

Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial hypocontractility is the major underlying mechanism,...
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Identification of the Marker-Genes for Dioxin(2,3,7,8-tetradibenzo-p-dioxin)-Induced Immune Dysfunction by Using the High-Density Oligonucleotide Microarray

Kim JA, Lee EJ, Kim HL

  • KMID: 2166168
  • Genomics Inform.
  • 2004 Jun;2(2):75-80.
In a variety of animal species, the perinatal exposure of experimental animals to the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) leads to the immune dysfunction, which is more severe and persistent than that caused...
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The Analysis of Epidermal Proteins in Patients with Psoriasis by Two-Dimensional Gel Electrophoresis

Lee DH, Lee KH, Park YK

  • KMID: 2303030
  • Korean J Dermatol.
  • 2003 Feb;41(2):207-213.
BACKGROUND: Psoriasis is a common, chronic, recurrent, inflammatory disease of the skin characterized by circumscribed, erythematous, thick plaques covered by silvery white scales. Although many researchers are working hard on...
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