Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

42 results
Display

The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis

Kim SK, Cho SM, Kim H, Seok H, Kim SO, Kwon TK, Chang JS

  • KMID: 2154238
  • Exp Mol Med.
  • 2013 Apr;45(4):e19.
New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Isolation of Endothelial Progenitor Cells from Cord Blood and Induction of Differentiation by Ex Vivo Expansion

Shin JW, Lee DW, Kim MJ, Song KS, Kim HS, Kim HO

Endothelial progenitor cells (EPCs) have been reported to possess the capacity to colonize vascular grafts and hold promise for therapeutic neovascularization. However, limited quantities of EPCs have been the major...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Inhibitory Effect of Curcumin on the Growth of Human Colon Cancer Cells (HT-29, WiDr) in vitro

Kim KH, Park HY, Nam JH, Park JE, Kim JY, Park MI, Chung KO, Park KY, Koo JY

  • KMID: 772765
  • Korean J Gastroenterol.
  • 2005 Apr;45(4):277-284.
BACKGROUND/AIMS: The effects of curcumin on the growth of human colon cancer cell lines, HT-29 and WiDr cells were examined and the effects of 5-fluorouracil (5-FU) were also studied....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of Recombinant Human BMP-7, Prepared from a COS-7 Expression System, on the Proliferation and Differentiation of Rat Newborn Calvarial Osteoblasts

Lee DH, Suh H, Han DW, Park BJ, Lee JW, Park JC

A family of proteins, the bone morphogenetic proteins (BMPs), which promote osteoblast differentiation and bone mineralization, have recently been identified. One, BMP-7, has shown the ability to induce cartilage and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Nitric Oxide on the Proliferation of Cultured Porcine Trabecular Meshwork Cells

Kim JW, Heo H, Lee HW

To investigate the effect of nitric oxide (NO) on the proliferation of trabecular meshwork (TM) cells, primarily cultured porcine TM cells were exposed to NO donor (SNAP, -nitroso-N-acetyl-D, L-penicillamine) with...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of Tamoxifen on Human Hepatocelluar Carcinoma Cell Proliferation and Transforming Growth Factor-beta1 Expression

Shin JW, Chung YH, Park MI, Kim JA, Choi MH, Lee YJ, Ryu SH, Park NH, Lee HC, Lee YS, Suh DJ, Yu ES

  • KMID: 1011390
  • Korean J Hepatol.
  • 2003 Mar;9(1):10-16.
BACKGROUND/AIMS: Tamoxifen has been tried in patients with hepatocellular carcinoma (HCC), however, its inhibitory mechanism remains unknown. In this study, we evaluated the effects of tamoxifen on HCC cell...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-HER2/neu Peptide Producing Vector System for Biologic Therapy - Is It Possible to Mass-produce the Peptide?

Park BW, Kim KS, Heo MK, Lee KS, Kim EK, Kim KS

A humanized monoclonal antibody against HER2 has been using in a clinical setting and has been shown to possess therapeutic properties. A mimetic peptide against HER2 was also reported to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain

Kim KS, Hong YK, Lee Y, Shin JY, Chang SI, Chung SI, Joe YA

  • KMID: 1119342
  • Exp Mol Med.
  • 2003 Dec;35(6):578-585.
The serine protease urokinase-type plasminogen activator (uPA) is implicated in pericellular proteolysis in a variety of physiological and pathological processes including angiogenesis and tumor metastasis. The kringle domain of uPA...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway

Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY

  • KMID: 1093610
  • Exp Mol Med.
  • 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Expression and Regulation of Endothelial Nitric Oxide Synthase by Vascular Endothelial Growth Factor in ECV 304 Cells

Park JS, Hong GR, Baek SW, Shin DG, Kim YJ, Shim BS

Nitric oxide (NO) seems to play a pivotal role in the vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation. This study was designed to investigate the role and intracellular signal...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neural cell adhesion molecule (NCAM) promotes the differentiation of hippocampal precursor cells to a neuronal lineage, especially to a glutamatergic neural cell type

Shin MH, Lee EG, Lee SH, Lee YS, Son H

  • KMID: 1121093
  • Exp Mol Med.
  • 2002 Dec;34(6):401-410.
Rat hippocampal precursor cells isolated from hippocampi of embryonic day 16.5 (E16.5) rat embryos were found to proliferate in the presence of basic fibroblast growth factor. Addition of soluble...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Requirement of Metabolic Activation for Estrogenic Activity of Pueraria mirifica

Lee YS, Park JS, Cho SD, Son JK, Cherdshewasart W, Kang KS

  • KMID: 1097343
  • J Vet Sci.
  • 2002 Dec;3(4):273-277.
A wide range of chemicals derived from plant and human-made xenobiotics are reported to have hormonal activities. The present study was performed to examine the estrogenic effect of Kwao Keur,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Interaction of TGF-beta1 and rhBMP-2 on Human Bone Marrow Stromal Cells Cultured in Collagen Gel Matrix

Kim MK, Niyibizi C

Transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-2 (BMP-2) are abundant proteins in the bone matrix. However, their interaction in controlling osteoblast differentiation is not clearly understood. In this study,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
TGF-betas Synthesized by RPE Cells Have Autocrine Activity on Mesenchymal Transformation and Cell Proliferation

Lee SC, Kim SH, Koh HJ, Kwon OW

The present study investigated the effects of transforming growth factor (TGF)-beta on retinal pigment epithelial (RPE) transformation in a simplified model and also whether or not TGF-beta exhibits similar proliferation...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines

Duda RB, Kang SS, Archer SY, Meng S, Hodin RA

American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Inhibition of rac1 Reduces PDGF-induced Reactive Oxygen Species and Proliferation in Vascular Smooth Muscle Cells

Kong G, Lee S, Kim KS

In vascular smooth muscle cells, reactive oxygen species (ROS) were known to mediate platelet-derived growth factor (PDGF)-induced cell proliferation and NADH/NADPH oxidase is the major source of ROS. NADH/NADPH oxidase...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Detection of Telomerase Activity in Psoriasis Lesional Skin and Correlaton with Ki-67 Expression and Suppression by Retinoic Acid

Jang HS, Oh CK, Jo JH, Kim YS, Kwon KS

Telomerase activity is usually detected in most tumor tissues but not in normal tissues. Recently, there is increasing evidence that telomerase activity is associated with cell proliferation without malignancy, whereas...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Varying Effects of Intravenous Immunoglobulin on Mononuclear Cell Proliferation In Vitro

Lee KY, Koh DK, Lee JS, Whang KT

Intravenous immunoglobulin (IVIG) is being increasingly used to treat numerous immune-mediated diseases. However, there is a paucity of knowledge on the specific mode of action of IVIG in vivo. In...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of short-term ethanol on the proliferative response of Swiss 3T3 cells to mitogenic growth factors

Yeo EJ, Lim HK, Park SC

  • KMID: 755081
  • Exp Mol Med.
  • 2000 Sep;32(3):161-169.
Both adaptive and deleterious responses of cells to ethanol are likely triggered by short-term interactions of the cells with ethanol. Many studies have demonstrated the direct effect of ethanol...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: interim analysis

Iqbal MP, Burney IA, Sultana F, Mehboobali N, Siddiqui T

  • KMID: 1109307
  • Exp Mol Med.
  • 2000 Jun;32(2):84-87.
The precise mechanism whereby granulocytes proliferate when haematopoietic colony stimulating factors (CSFs) are used in neutropenic cancer patients is poorly understood. The purpose of this study was to investigate whether...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr