- The effects of laminin on the characteristics and differentiation of neuronal cells from epidermal growth factor-responsive neuroepithelial cells
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Park DS, Park JS, Yeon DS
- KMID: 711537
- Yonsei Med J.
- 1998 Apr;39(2):130-140.
- doi: 10.3349/ymj.1998.39.2.130
Many extracellular matrix molecules are expressed in the embryonic nervous system and there is some evidence that they are important regulators of neural development. Of these molecules, laminin appears to... -
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- Neural cell adhesion molecule (NCAM) promotes the differentiation of hippocampal precursor cells to a neuronal lineage, especially to a glutamatergic neural cell type
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Shin MH, Lee EG, Lee SH, Lee YS, Son H
- KMID: 1121093
- Exp Mol Med.
- 2002 Dec;34(6):401-410.
Rat hippocampal precursor cells isolated from hippocampi of embryonic day 16.5 (E16.5) rat embryos were found to proliferate in the presence of basic fibroblast growth factor. Addition of soluble... -
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- Enhanced induction of Bax gene expression in H460 and H1299 cells with the combined treatment of cisplatin and adenovirus mediated wt-p53 gene transfer
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Choi JH, Ahn KS, Kim JG, Hong YS
- KMID: 927130
- Exp Mol Med.
- 2000 Mar;32(1):23-28.
Cytotoxic effect of either cisplatin or p53 gene transfection of lung cancer cells may be different depending on the p53 status of cells. We investigated cytotoxic effects on the combined... -
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- The biologic role of ganglioside in neuronal differentiation: effects of GM1 ganglioside on human neuroblastoma SH-SY5Y cells
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Lee MC, Lee WS, Park CS, Juhng SW
- KMID: 1422174
- J Korean Med Sci.
- 1994 Apr;9(2):179-187.
- doi: 10.3346/jkms.1994.9.2.179
Human neuroblastoma SH-SY5Y cell is a cloned cell line which has many attractive features for the study of neuronal proliferation and neurite outgrowth, because it has receptors for insulin, IGF-I... -
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- Ideal concentration of growth factors in rabbit's flexor tendon culture
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Kang HJ, Kang ES
- KMID: 1099875
- Yonsei Med J.
- 1999 Feb;40(1):26-29.
- doi: 10.3349/ymj.1999.40.1.26
Growth factors have the ability to stimulate matrix synthesis and cell proliferation in rabbit flexor tendon. Maximal stimulation effects of growth factors have a wide variation. It depends... -
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- The mechanism of antiproliferative effect of desferrioxamine on human hepatoma cell lines
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Kim DY, Kim WH, Kang JK, Park IS, Kwon OH
- KMID: 1381218
- Yonsei Med J.
- 1994 Mar;35(1):62-71.
- doi: 10.3349/ymj.1994.35.1.62
We investigated the effect of desferrioxamine (DFO), an iron chelator, on the DNA synthesis and the cell cycle of cultured hepatoma cells. Using Hep 3B cells as the hepatoma cell... -
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- Varying Effects of Intravenous Immunoglobulin on Mononuclear Cell Proliferation In Vitro
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Lee KY, Koh DK, Lee JS, Whang KT
- KMID: 2157559
- J Korean Med Sci.
- 2001 Oct;16(5):544-548.
- doi: 10.3346/jkms.2001.16.5.544
Intravenous immunoglobulin (IVIG) is being increasingly used to treat numerous immune-mediated diseases. However, there is a paucity of knowledge on the specific mode of action of IVIG in vivo. In... -
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- Effect of suramin on differentiation of human stomach cancer cell lines
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Choe G, Kim WH, Park JG, Kim YI
- KMID: 1081036
- J Korean Med Sci.
- 1997 Oct;12(5):433-442.
- doi: 10.3346/jkms.1997.12.5.433
This study was designed to demonstrate that differentiation of stomach cancer cells can be modified by microenvironmental change and to look for a method inducing or promoting tumor cell... -
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- TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells
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Lee JH, Park BJ, Park JH, Yang MH, Chi SG
- KMID: 755040
- Exp Mol Med.
- 1999 Sep;31(3):126-133.
To characterize the TGF-beta1 response of monocytic leukemia cells, we analyzed the effects of TGF-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic U937 cells. Treatment of cells with TGF-beta1 in... -
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- Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway
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Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY
- KMID: 1093610
- Exp Mol Med.
- 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)... -
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- The effect of dichlorotriazinyl aminofluorescein on human keratocytes in vitro
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Wee WR, Rofougaran R, Pakkar A, Hayashi S, McDonnell
- KMID: 1735160
- Korean J Ophthalmol.
- 1996 Dec;10(2):63-67.
- doi: 10.3341/kjo.1996.10.2.63
Dichlorotriazinyl aminofluorescein (DTAF) has been used to stain corneal stromal collagen as part of in vivo animal experiments for many years. Toxicity of this drug, if present, might alter the... -
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- Effect of Nitric Oxide on the Proliferation of Cultured Porcine Trabecular Meshwork Cells
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Kim JW, Heo H, Lee HW
- KMID: 754335
- Korean J Ophthalmol.
- 2003 Jun;17(1):1-6.
- doi: 10.3341/kjo.2003.17.1.1
To investigate the effect of nitric oxide (NO) on the proliferation of trabecular meshwork (TM) cells, primarily cultured porcine TM cells were exposed to NO donor (SNAP, -nitroso-N-acetyl-D, L-penicillamine) with... -
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- Interaction of TGF-beta1 and rhBMP-2 on Human Bone Marrow Stromal Cells Cultured in Collagen Gel Matrix
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Kim MK, Niyibizi C
- KMID: 720631
- Yonsei Med J.
- 2001 Jun;42(3):338-344.
- doi: 10.3349/ymj.2001.42.3.338
Transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-2 (BMP-2) are abundant proteins in the bone matrix. However, their interaction in controlling osteoblast differentiation is not clearly understood. In this study,... -
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- The effective concentration and exposure time of mitomycin-C for the inhibition of lens epithelial cell proliferation in rabbit eyes
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You YS, Lim SJ, Chung HS, Lee YG, Kim CY, Hong YJ
- KMID: 1758507
- Yonsei Med J.
- 2000 Apr;41(2):185-189.
- doi: 10.3349/ymj.2000.41.2.185
The proliferation of residual lens epithelial cells following cataract surgery is assumed to be a major cause of posterior capsular opacification. To assess the efficacy of mitomycin-C in preventing posterior... -
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- The effect of lovastatin on proliferation of cultured rat mesangial and aortic smooth muscle cells
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Choi KH, Kang SW, Lee SW, Lee HY, Han DS, Kang BS
- KMID: 1123180
- Yonsei Med J.
- 1995 Jun;36(3):251-261.
- doi: 10.3349/ymj.1995.36.3.251
In order to investigate the anti-proliferative effect of 3-hydroxy-3-methylglutaryl coenzyme. A reductase inhibitor, we evaluated the effects of lovastatin on DNA replication and the proliferation of rat mesangial and aortic... -
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- The effect of anti-hypertensive drugs on DNA synthesis and proliferation of ultured rat aortic smooth muscle cells
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Kang SW, Lee IH, Choi KH, Lee HY, Han DS
- KMID: 699945
- Yonsei Med J.
- 1997 Jun;38(3):160-166.
- doi: 10.3349/ymj.1997.38.3.160
The aim of this study was to elucidate the effects of anti-hypertensive drugs, nifedipine, furosemide, hydrochlorothiazide, captopril, and atenolol on DNA synthesis and proliferation of cultured rat aortic... -
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- Effect of short-term ethanol on the proliferative response of Swiss 3T3 cells to mitogenic growth factors
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Yeo EJ, Lim HK, Park SC
- KMID: 755081
- Exp Mol Med.
- 2000 Sep;32(3):161-169.
Both adaptive and deleterious responses of cells to ethanol are likely triggered by short-term interactions of the cells with ethanol. Many studies have demonstrated the direct effect of ethanol... -
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- Synthesized TGF-beta s in RPE regulates cellular proliferation
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Lee SC, Seong GJ, Kim SH, Kwon OW
- KMID: 1081831
- Korean J Ophthalmol.
- 1999 Jun;13(1):16-24.
- doi: 10.3341/kjo.1999.13.1.16
Retinal pigment epithelial (RPE) cells transdifferentiate in culture, a transition which is accompanied by a shift in biological activity. The present study investigates whether transforming growth factor (TGF)-beta has the... -
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- The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis
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Kim SK, Cho SM, Kim H, Seok H, Kim SO, Kwon TK, Chang JS
- KMID: 2154238
- Exp Mol Med.
- 2013 Apr;45(4):e19.
New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report... -
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- Effect of gamma-interferon on fibroblast proliferation and collagen synthesis after glaucoma filtering surgery in white rabbits
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Lee YC, Park MH, Baek NH
- KMID: 1735081
- Korean J Ophthalmol.
- 1991 Dec;5(2):59-67.
- doi: 10.3341/kjo.1991.5.2.59
Failure of a glaucoma filtering operation mainly results from scarring at the filtering wound, and postoperative proliferation and migration of fibroblasts play an important role histologically in the formation of... -
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