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Autocrine Extracellular Signal-regulated Kinase Activation in Normal Human Keratinocytes is not Interrupted by Calcium Triggering and is Involved in the Control of Cell Cycle at the Early Stage of Calciuminduced Differentiation

Park GT, Kim HY, Kim EK, Yang JM

Normal human epidermal keratinocytes (NHEK) respond to the autocrine activated extracellular signal-regulated kinase (ERK) signaling pathway, which contributes to the survival of keratinocytes. However, during the condition of calcium-induced differentiation,...
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Methyl-beta-cyclodextrin inhibits cell growth and cell cycle arrest via a prostaglandin E(2) independent pathway

Choi YA, Chin BR, Rhee DH, Choi HG, Chang HW, Kim JH, Baek SH

  • KMID: 755669
  • Exp Mol Med.
  • 2004 Feb;36(1):78-84.
Methyl-beta-cyclodextrin, a cyclic oligosaccharide known for its interaction with the plasma membrane induces several events in cells including cell growth and anti-tumor activity. In this study, we have investigated the...
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Changes in expression of cell cycle regulators after G1 progression upon repetitive thioacetamide treatment in rat liver

Hong SH, Lee GD, Chung JY, Cho KS, Park SH, Kim IH, Jeong JS

  • KMID: 755208
  • Exp Mol Med.
  • 2002 Nov;34(5):361-366.
Repetitive low dose thioacetamide (TA) treatment of hepatocytes was found to induce cells in G2 arrest. In the present study, an attempt was made to investigate alterations in expression of...
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