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Pattern of Apoptosis by NS398, a Selective COX-2 Inhibitor, in Hepatocellular Carcinoma Cell Lines

Park MK, Kim MK, Kim JC, Sung YK

  • KMID: 2166122
  • Cancer Res Treat.
  • 2005 Oct;37(5):313-317.
PURPOSE: NS398, a selective COX-2 inhibitor, is known to inhibit the growth of COX-2 expressing hepatocellular carcinoma cells. The present study investigated whether the cytotoxic effect of NS398 was COX-2...
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Genistein-Induced Apoptosis of p815 Mastocytoma Cell

Song KH, Song KH, Kim KH

BACKGROUND: Numerous studies demonstrated that genistein induced the decrease of proliferation and apoptosis in a variety of cells. However, there is no report about the effect of genistein on proliferation...
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Characterization of Cigarette Smoke Extract (CSE)-induced Cell Death in Lung Epithelial Cells

Choi EK, Kim YS, Park JS, Jee YK, Lee KY

Emphysema is characterized by air space enlarge?ment and alveolar destruction. The mechanism responsible for the development of emphysema was thought to be protease/antiprotease imbalance and oxidative stress. A very recent...
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Peroxisome proliferator-activated receptor gamma ligands exert antineoplastic effects in hepatocellular carcinoma cells

Chae MJ, Shim J, Kim BH, Hwangbo Y, Lee YJ, Ha SH, Jang JY, Dong SH, Kim HJ, Chang YW, Chang R

  • KMID: 2258779
  • Korean J Med.
  • 2008 Sep;75(3):288-299.
BACKGROUND/AIMS: Thiazolidinediones, which are synthetic insulin sensitizers, are known activators of peroxisome proliferator-activated receptor gamma (PPARgamma). PPARgamma ligands, including endogenous 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2), are thought to elicit antineoplastic effects in...
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Antineoplastic effect of endogenous peroxisome proliferator-activated receptor gamma ligand, 15-deoxy-delta(12,14)-prostaglandin J2, on cholangiocarcinoma cells

Jung SH, Kim BH, Kim YI, Shim J, Hwangbo Y, Jang JY, Dong SH, Kim HJ, Chang YW, Chang R, Kim DG

  • KMID: 2259206
  • Korean J Med.
  • 2010 Jan;78(1):75-86.
BACKGROUND/AIMS: Peroxisome proliferator-activated receptor (PPAR)-gamma ligand is known to inhibit the growth of several kinds of cancer cells, yet its effect on cholangiocarcinoma is indecisive. We investigated the effect of...
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6-hydroxydopamine Induces Neuronal Apoptosis in Mouse Cortical Cell Cultures

Jung JH, Kang HJ, Sohn S, Chung YK, Gwag BJ, Noh JS

  • KMID: 2340467
  • J Korean Neuropsychiatr Assoc.
  • 2000 May;39(3):656-665.
OBJECTIVES: We examined the patterns of cell death induced by the 6-hydroxydopamine, a selective dopaminergic toxin that used to produce Parkinson's disease model. METHOD: Neocortices from 14- or 15-day-old fetal mice...
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