- Mutational Analysis of Caspase-7 and 8 Genes in Non-small Cell Lung Cancer
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Soung YH, Lee JW, Moon SW, Jo KH, Wang YP, Kim SY, Nam SW, Park WS, Lee JY, Yoo NJ, Lee SH
- KMID: 1895268
- J Lung Cancer.
- 2005 Jun;4(1):38-41.
PURPOSE : Several lines of evidence have indicated that deregulation of apoptosis is involved in the mechanism of cancer development. Caspase-8 activation plays a central role in the initiation phase... -
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- Mechanism Underlying Curcumin-induced Apoptosis and Cell Cycle Arrest on SCC25 Human Tongue Squamous Cell Carcinoma Cell Line
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Moon JB, Lee KH, Kim IR, Kim GC, Kwak HH, Park BS
- KMID: 1703488
- Int J Oral Biol.
- 2014 Mar;39(1):23-33.
Several studies have shown that curcumin, which is derived from the rhizomes of turmeric, possesses antimicrobial, antioxidant and anti-inflammatory properties. The antitumor properties of curcumin have also now been demonstrated... -
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- Apoptotic Effects of Co-Treatment with a Chios Gum Mastic and Eugenol on G361 Human Melanoma Cells
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Jo JB, Oh SH, Kim IR, Kim GC, Kwak HH, Park BS
- KMID: 2170780
- Int J Oral Biol.
- 2013 Sep;38(3):101-110.
We investigated the synergistic apoptotic effects of co-treatments with Chios gum mastic (CGM) and eugenol on G361 human melanoma cells. An MTT assay was conducted to investigate whether this co-treatment... -
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- Cellular Effects of Troglitazone on YD15 Tongue Carcinoma Cells
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Ta Thi L, Yoo H
- KMID: 2354198
- Int J Oral Biol.
- 2016 Sep;41(3):113-118.
- doi: 10.11620/IJOB.2016.41.3.113
An FDA approved drug for the treatment of type II diabetes, Troglitazone (TRO), a peroxisome proliferator–activated receptor gamma agonist, is withdrawn due to severe idiosyncratic hepatotoxicity. In the search for... -
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- Mechanism Underlying NaF-induced Apoptosis and Cell Cycle Arrest on G361 Human Melanoma Cell Line
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Kim DK, Sohn HJ, Kim IR, Kim GC, Park BS, Kwak HH
- KMID: 1449615
- Korean J Phys Anthropol.
- 2011 Dec;24(4):203-216.
Fluoride is widely used in dentistry to prevent dental caries, even though the safety of fluoride is a controversial issue. There are no known adverse effects of long-term fluoride ingestion... -
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- Mechanism of FHIT-Induced Apoptosis in Lung Cancer Cell Lines
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Yoo JS, Kim CH
- KMID: 2132973
- Tuberc Respir Dis.
- 2004 May;56(5):450-464.
- doi: 10.4046/trd.2004.56.5.450
BACKGROUND: The FHIT (fragile histidine triad) gene is a frequent target of deletions associated with abnormal RNA and protein expression in lung cancer. Previous studies have shown FHIT gene transfer... -
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- Apoptotic Effects of A Cisplatin and Eugenol Co-treatment of G361 Human Melanoma Cells
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Park JY, Jo JB, Kim IR, Kim GC, Kwak HH, Park BS
- KMID: 2170747
- Int J Oral Biol.
- 2011 Sep;36(3):155-162.
Eugenol (4-allyl-2-methoxyphenol) is a naturally occurring phenolic compound that is widely used in dentistry as a component of zinc oxide eugenol cement that is commonly applied to the mouth environment.... -
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- Tannic acid-induced apoptosis in FaDu hypopharyngeal squamous cell carcinoma
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Ta LT, Nguyen TT, Yoo H
- KMID: 2452746
- Int J Oral Biol.
- 2019 Jun;44(2):43-49.
- doi: 10.11620/IJOB.2019.44.2.43
Tannic acid (TA) is a water-soluble polyphenol compound found in various herbal plants. We investigated the chemopreventive effects of TA on FaDu hypopharyngeal squamous carcinoma cells. In an 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide... -
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- Apoptotic Effect of Co-treatment with Curcumin and Cisplatin on SCC25 Human Tongue Squamous Cell Carcinoma Cell Line
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Sohn HJ, Kim IR, Kim YH, Kim GC, Kwak HH, Park BS
- KMID: 1727434
- Int J Oral Biol.
- 2014 Sep;39(3):159-167.
Curcumin is a widely used flavoring agent in food, and it has been reported to inhibit cell growth, to induce apoptosis, and to have antitumor activity in many cancers. Cisplatin... -
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- Arsenic Trioxide (As2O3) Induced Apoptosis in NB4 Cell lines
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Park KB, Hong DS, Suh WS, Lee NS, Park SG, Won JH, Jung HJ, Kim SJ, Hong YS, Jin JY, Park HS, Shin SM
- KMID: 1641957
- Korean J Hematol.
- 2002 Aug;37(3):200-211.
BACKGROUND: Recently, inorganic arsenic trioxide (As2O3) was reported to induce complete remission in a high proportion of patients with refractory acute promyelocytic leukemia (APL). To illustrate cellular and molecular mechanisms... -
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- Apoptotic Effect of Co-Treatment with a Natural Product, Chios Gum Mastic, and a Proteasome Inhibitor, Lactacystin, on Human Osteosarcoma Cells
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Baek CJ, Heo JY, Kim GC, Kwak HH, Kim IR, Lee SE, Kim CH, Jeong NY, Park BS
- KMID: 1484903
- Korean J Anat.
- 2008 Jun;41(2):129-138.
Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently, it was reported that CGM... -
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- Apoptotic Effect of Combination Treatment with a Proteasome Inhibitor, Lactacystin, and a Histone Deacetylase Inhibitor, Trichostatin A, on MCF-7 Cells
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Kim GC, Shin YJ, Kim IR, Lee MH, Hwang YS, Gil YG, Park BS
- KMID: 1510218
- Korean J Anat.
- 2006 Dec;39(6):443-452.
Although much information has been accumulated about the synergistic interaction of proteasome inhibitors and HDAC inhibitors to induce apoptosis in a certain type of cells, much less is known currently... -
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- Knockdown of Bcl-xL Enhances Growth-Inhibiting and Apoptosis-Inducing Effects of Resveratrol and Clofarabine in Malignant Mesothelioma H-2452 Cells
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Lee YJ, Hwang IS, Lee YJ, Lee CH, Kim SH, Nam HS, Choi YJ, Lee SH
- KMID: 2069926
- J Korean Med Sci.
- 2014 Nov;29(11):1464-1472.
- doi: 10.3346/jkms.2014.29.11.1464
Mcl-1 and Bcl-xL, key anti-apoptotic proteins of the Bcl-2 family, have attracted attention as important molecules in the cell survival and drug resistance. In this study, we investigated whether inhibition... -
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- Ethanol Extracts of Angelica decursiva Induces Apoptosis in Human Oral Cancer Cells
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Lee MH, Kim MM, Kook JK, Kim DK, Kim HR, Kim HJ, Kim CS
- KMID: 1457216
- Int J Oral Biol.
- 2010 Dec;35(4):215-220.
Angelica decursiva has been used in Korean traditional medicine as an antitussive, an analgesic, an antipyretic and a cough remedy. However, its anti-cancer properties have not yet been well defined.... -
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- Induction of apoptosis by Hibiscus protocatechuic acid in human uterine leiomyoma cells
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Shon WK, Cho CH, Ramachandran S, Song DK, Shin SJ, Kwon SH, Cha SD
- KMID: 1979501
- Korean J Gynecol Oncol.
- 2008 Mar;19(1):48-56.
- doi: 10.3802/kjgo.2008.19.1.48
OBJECTIVE: Hibiscus protocatechuic acid (PCA) is a food-derived polyphenol antioxidants used as a food additive and a traditional herbal medicine. In this study, PCA was to determine its effect on... -
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