- Inflammatory Bowel Diseases and Inflammasome
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Kim JM
- KMID: 1043328
- Korean J Gastroenterol.
- 2011 Dec;58(6):300-310.
- doi: 10.4166/kjg.2011.58.6.300
Inflammatory bowel disease (IBD), the most important entities being ulcerative colitis and Crohn's disease, are chronic, relapsing and remitting inflammatory conditions that result from chronic dysregulation of the mucosal immune... -
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- NLRP3 Inflammasome and Host Protection against Bacterial Infection
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Kim JJ, Jo EK
- KMID: 1777675
- J Korean Med Sci.
- 2013 Oct;28(10):1415-1423.
- doi: 10.3346/jkms.2013.28.10.1415
The inflammasome is a multi-protein complex that induces maturation of inflammatory cytokines interleukin (IL)-1beta and IL-18 through activation of caspase-1. Several nucleotide binding oligomerization domain-like receptor family members, including NLRP3,... -
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- IL-1beta Acts in Synergy with Endogenous IL-1beta in A375-S2 Human Melanoma Cell Apoptosis Through Mitochondrial Pathway
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Wang C, Wang MW, Tashiro SI, Onodera S, Ikejima T
- KMID: 1712732
- J Korean Med Sci.
- 2005 Aug;20(4):555-561.
- doi: 10.3346/jkms.2005.20.4.555
Interleukin-1beta (IL-1beta) is a pivotal proinflammatory cytokine. To investigate the mechanism of IL-1beta-induced cell death in human malignant melanoma A375-S2 cells, MTT assay, photomicroscopical observation, DNA agarose gel electrophoresis, radioimmunoassay... -
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