- 2-Deoxy-D-glucose regulates dedifferentiation through beta-catenin pathway in rabbit articular chondrocytes
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Yu SM, Kim HA, Kim SJ
- KMID: 1104210
- Exp Mol Med.
- 2010 Jul;42(7):503-513.
- doi: 10.3858/emm.2010.42.7.051
2-deoxy-D-glucose (2DG) is known as a synthetic inhibitor of glucose. 2DG regulates various cellular responses including proliferation, apoptosis and differentiation by regulation of glucose metabolism in cancer cells. However, the... -
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- ERK-1/-2 and p38 Kinase Oppositely Regulate 15-deoxy-delta(12,14)-prostaglandinJ2-Induced PPAR-gamma Activation That Mediates Dedifferentiation But Not Cyclooxygenase-2 Expression in Articular Chondrocytes
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Yoon EK, Lee WK, Lee JH, Yu SM, Hwang SG, Kim SJ
- KMID: 1785763
- J Korean Med Sci.
- 2007 Dec;22(6):1015-1021.
- doi: 10.3346/jkms.2007.22.6.1015
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a ligand-activated transcription factor and plays an important role in growth, differentiation, and inflammation in different tissues. In this study, we investigated the effects... -
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