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Effect of Extract of Seeds of Carthamus tinctorius L. on Mineralization in Periodontal Ligament Cells and Osteoblastic Cells

Kang JG, You HK, Shin HS

The main goal for the treatment of periodontal diseases is the regeneration of lost cementum, bone and connective tissue. Clinical and histological research suggests that it is possible to restore...
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Carthamus tinctorius L. Increases BMP-2 Gene Expression during Bone Fracture Healing in Rats

Lee KH, Sohn OJ, Ahn JC, Kim YW, Park SY, Kim JY

  • KMID: 2285325
  • Korean J Physiol Pharmacol.
  • 2006 Jun;10(3):143-147.
Carthamus tinctorius L.is known to improve fracture healing, and bone morphogenetic proteins (BMPs) are associated with the formation and healing process of bone. BMP-2 and BMP-7 are two of the...
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A Case of Cardiac Arrest with Pulseless Ventricular Tachycardia Induced by Carthamus tinctorius L. (safflower) Seed Intoxication

Lee DW, Lee JW, Moon HJ, Yoo BD, Jun DH

Carthamus tinctorius L. is commonly known as safflower. This plant is cultivated mainly for its seed, which is used as essential oil and hot water extract. C. tinctorius has recently...
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Effects of Carthamus tinctorius on Semen Quality and Gonadal Hormone Levels in Partially Sterile Male Rats

Bahmanpour S, Vojdani Z, Panjehshahin MR, Hoballah H, Kassas H

PURPOSE: Traditional herbal medicine is just one of the many different approaches using plants in the remedy of diseases. Carthamus tinctorius (CT) or safflower is a popular plant that is...
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Occurrence of Powdery Mildew on Safflower Caused by Sphaerotheca fuliginea in Korea

Kwon JH, Kang SW, Lee HS, Park CS

  • KMID: 2312313
  • Mycobiology.
  • 2000 Mar;28(1):51-53.
The powdery mildew of safflower (Carthamus tinctorius L.) extensively occurred at 1999 at the experimental farm of Kyongsangnam-do Agricultural Research and Extension Services. Both sides of the leaves and the...
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Effects of some herbal drugs on gingival fibroblast and periodontal ligament cellular activity

Doo JS, Kang JK, You HK, Shin HS

Healing of periodontal tissues require the migration and proliferation of gingival fibroblasts and periodontal ligament cells. There is many evidences that the some agents like cytokines and polypeptide growth factors...
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The biologic effects of safflower(Carthamus tinctorius Linne') extract and Dipsasi Radix extract on periodontal ligament cells and osteoblastic cells

Rhyu IC, Lee YM, Ku Y, Bae KW, Chung CP

Safflower(Carthamus tinctorius Linne'has been traditionally used for the treatment of blood stasis, and Dipsasi Radix has been used as a drug for fracture in Chinese medicine. The purpose of present...
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A Study of Safflower Seed Extracts on Bone Formation in Vitro

Lee SJ, Choi HC, Sun KJ, Song JB, Pi SH, You HK, Shin HS

The ultimate goal of periodontal therapy is the regeneration of periodontal tissue and the repair of function. For more than a decade there have been many efforts to develop ma-...
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Antimicrobial effects of natural extracts on bacteria isolated from the uterus of Hanwoo (Korean native cattle)

Park B, Kim K, Cho Y, Park S, Lee J, Jung BD, Kwon YS, Park JJ, Hahn TW

  • KMID: 1726746
  • Korean J Vet Res.
  • 2014 Sep;54(3):159-164.
Bacterial infection of the uterus in Hanwoo can kill embryos. Therefore, many antibiotics have been used to treat this infection in the uterus of repeat breeders. Incorrect use of antibiotics...
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A Case of Foreign Body Granuloma Caused by Injection of Safflower Seed Extracts

Lee JW, Yoo KH, Kim JY, Li K, Seo SJ, Hong CK

  • KMID: 2301698
  • Korean J Dermatol.
  • 2009 Feb;47(2):242-244.
Foreign body granuloma is a chronic, proliferative, inflammatory reaction caused by persistent poorly biodegradable tissue irritants. Currently, many injectable materials are being used extensively for soft tissue augmentation. Although considered...
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The effect of safflower seed fraction extract on periodontal ligament fibroblast and MC3T3-E1 cell in vitro

Huh JS, Kang JH, Yoo YJ, Kim CS, Cho KS, Choi SH

Recently, use of natural medicine is getting more attention, and some of them are believed to be effective in the treatment of periodontitis. Among them, the seeds of safflower(Carthamus tinctorius...
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Anti-inflammatory Effect of Methanol Extract from Safflower Seeds

Kim HJ

Periodontitis is an inflammatory disease, which destroys the connective tissue and the alveolar bone. Recently, it has been suggested that the effect of natural substances could be induced into an...
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Effects of Safflower Seed Extracts and Bovine Bone on Regeneration of Bone Defects in Mongrel Dogs

Seo JJ, Kim T, Pi SH, Yun GY, You HK, Shin HS

Many natural medicines have been studied for their capacity and effects of anti-bacterial, anti-inflammatory and regenerative potential in periodontal tissues. Safflower seed has been traditionally used as a drug for...
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Effects of Locally Applicated Safflower Seeds Extract on Bone Regeneration of Rat Calvarial Defects

Kim DK, Hong SW, You KT, Seo JJ, Kim HS, You HK, Shin HS

The ultimate goal of periodontal treatment is the regeneration of periodontal tissues which have been lost due to periodontal disease. Recently, many natural medicines have been studied for their potential...
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Effect of Extracts from Safflower Seeds on Osteoblastic Differentiation and Intracellular Free Calcium Concentration in MC3T3-E1 Cells

Jang HO, Eom HS, Roh SB, Yun I

  • KMID: 2285310
  • Korean J Physiol Pharmacol.
  • 2005 Feb;9(1):55-62.
Very little research has been carried out on safflower seed for the prevention and treatment of the bone deficiency diseases, including osteoporosis, which are supported by scientific evidences. In the...
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Healing after Implantation of Bone Substitutes and Safflower Seeds Feeding in Rat Calvarial Defects

You KT, Choi KS, Yun GY, Kim EC, You HK, Shin HS

  • KMID: 2321549
  • J Korean Acad Periodontol.
  • 2000 Mar;30(1):91-103.
Many synthetic bone materials have been studied for their potential of regenerative effects in periodontal tissue. Safflower seeds have been traditionally used as a drug for the treatment of fracture...
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Comparative effect of dietary borage oil and safflower oil on anti-proliferation and ceramide metabolism in the epidermis of essential fatty acid deficient guinea pigs

Lee SR, Cho Y

PURPOSE: Borage oil (BO) and safflower oil (SO) are efficacious in reversing epidermal hyperproliferation, which is caused by the disruption of epidermal barrier. In this study, we compared the antiproliferative...
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Phytoestrogen-Induced Phosphorylation of MAP Kinase in Osteoblasts is Mediated by Membrane Estrogen Receptor

Park YH, Park HK, Lee HJ, Park SM, Choi SW, Lee WJ

  • KMID: 2285247
  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):165-170.
We have previously demonstrated that phytoestrogens isolated from safflower seeds significantly attenuated bone loss in ovariectomized rats, and directly stimulated proliferation and differentiation of cultured osteoblastic cells. In an attempt...
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The Effect of Safflower Seed or Matairesinol on Spontaneous Bone Formation in Surgically Induced Bone Defect in Young Rabbit

Song HR, Ra DK, Kim GS, Chang KC, Hwang JM, Yeon SC, Park HB, Choi SW

PURPOSE: To investigate the effect of defatted safflower seed or matairesinol on spontaneous bone formation in surgically induced bone defects in young rabbits MATERIALS AND METHODS: Bone defects(20% of original...
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Effect of Korean Traditional Tea Materials Water Extract on Hepatic Oxygen Free Radical Generating and Scavenging Enzyme Activities in Lead Administered Rats

Kim DJ, Cho SY, Shin KH, Lee MK, Kim MJ

  • KMID: 2269635
  • Korean J Nutr.
  • 2003 Mar;36(2):117-124.
This study was designed to test the effect of Korean traditional tea materials on oxygen-free radical metabolism in lead (Pb) -administered rats. Male rats were divided into normal, Pb-control (Pb-Con)...
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