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Dissecting the molecular mechanism of nuclear receptor action: transcription coactivators and corepressors

Lee JW, Cheong JH, Lee YC, Na SY, lee SK

  • KMID: 1109302
  • Exp Mol Med.
  • 2000 Jun;32(2):53-60.
No abstract available.
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Gastric Metastasis from Breast Cancer

Yoon SY, Shim KN

No abstract available.
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Lipid rafts are important for the association of RANK and TRAF6

Ha H, Kwak HB, Le SW, Kim HH, Lee ZH

  • KMID: 1109317
  • Exp Mol Med.
  • 2003 Aug;35(4):279-284.
Rafts, cholesterol- and sphingolipid-rich membrane microdomains, have been shown to play an important role in immune cell activation. More recently rafts were implicated in the signal transduction by members of...
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Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells

Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH

  • KMID: 1093633
  • J Vet Sci.
  • 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,...
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Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells

Park SN, Noh KT, Jeong YI, Jung ID, Kang HK, Cha GS, Lee SJ, Seo JK, Kang DH, Hwang TH, Lee EK, Kwon B, Park YM

  • KMID: 2154227
  • Exp Mol Med.
  • 2013 Feb;45(2):e8.
We evaluated the effectiveness of rhamnogalacturonan II (RG-II)-stimulated bone marrow-derived dendritic cells (BMDCs) vaccination on the induction of antitumor immunity in a mouse lymphoma model using EG7-lymphoma cells expressing ovalbumin...
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Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: potential role in intimal neovascularization

Kang SM, Kwon HM, Hong BK, Kim D, Kim IJ, Choi EY, Jang Y, Kim HS, Kim MS, Kwon HC

Neovascularization of the adventitial vasa vasorum with extension into the intima of atherosclerotic lesions is frequently observed, but its pathophysiological significance is still subject to debate. Recently, leptin, the product...
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Inflammatory Bowel Diseases and Inflammasome

Kim JM

Inflammatory bowel disease (IBD), the most important entities being ulcerative colitis and Crohn's disease, are chronic, relapsing and remitting inflammatory conditions that result from chronic dysregulation of the mucosal immune...
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Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity

Kim HS, Jeong SY, Lee JH, Kim BE, Kim JW, Jeong SW, Kim IK

  • KMID: 755099
  • Exp Mol Med.
  • 2000 Dec;32(4):197-203.
3-Deazaadenosine (DZA), one of the potent inhibitors of S-adenosylhomocysteine hydrolase, is known to possess several biological properties including an induction of apoptosis. To evaluate a possibility that DZA...
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Soluble glucocorticoid-induced TNF receptor (sGITR) induces inflammation in mice

Shin HH, Kim SG, Lee MH, Suh JH, Kwon BS, Choi HS

  • KMID: 1093607
  • Exp Mol Med.
  • 2003 Oct;35(5):358-364.
Glucocorticoid-induced TNF receptor (GITR) was a new member of the TNF/nerve growth factor receptor (TNFR/ NGFR) family and induced in murine T cells by dexamathasone. Recombinant soluble GITR (sGITR) induced...
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Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells.

Lim SY, Lee SC, Shin IC, Han JS

  • KMID: 1380228
  • Exp Mol Med.
  • 2002 Jul;34(3):201-210.
A20 murine lymphoma cells undergoing Fas-mediated apoptosis showed increase in the activity of phospholipase D (PLD), which is involved in proliferative or mitogenic cellular responses. Using A20 cell lines that...
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Low dietary inorganic phosphate affects the lung growth of developing mice

Xu CX, Jin H, Chung YS, Shin JY, Hwang SK, Kwon JT, Park SJ, Lee ES, Minai-Tehrani A, Chang SH, Woo MA, Noh MS, An GH, Lee KH, Cho MH

Inorganic phosphate (Pi) plays a critical role in diverse cellular functions, and regulating the Pi balance is accomplished by sodium-dependent Pi co-transporter (NPT). Pulmonary NPT has recently been identified in...
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