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In vivo antitumor effects of lactic acid bacteria on sarcoma 180 and mouse lewis lung carcinoma

Kim HY, Bae HS, Baek YJ

  • KMID: 1742116
  • J Korean Cancer Assoc.
  • 1991 Jun;23(2):188-196.
No abstract available.
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Antitumor and Antimetastatic Effects of Toxoplasma Gondii in Mice with Lewis Lung Carcinoma

Kim JO, Jung SS, Park HS, Kim MH, Lee YH, Kim SY

  • KMID: 2318364
  • Tuberc Respir Dis.
  • 2002 Apr;52(4):317-329.
BACKGROUND: Immunotherapy is another treatment modality for various cancers. There is little information on the antitumor effects of immunotherapy on implanted lung cancer mouse models. Toxoplasma gondii is able to...
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Effect of Interleukin-12 on the Expression of E-selectin in Mouse Model of Lewis Lung Carcinoma

Lee SH, Shin Y, Yoon HK, Lee SY, Kim SC, Kweon SS, Kim YK, Kim KH, Moon HS, Song JS, Park SH

BACKGROUND: Interleukin-12 (IL-12) can induce antitumor effects in vivo. This antitumor effect is associated with T cell infiltration but the effect of IL-12 on the steps of T cell migration...
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The Effects of Photodynamic Therapy with Photogem and Laser with Power Density of 600 mW/cm2 on Lewis Lung Carcinoma Cells Tumor Graft in Mouse

Kwon SJ, Kim JO, An JY, Jung SS, Lim HS, Song KS, Lee YH, Kim SY

  • KMID: 1881517
  • J Lung Cancer.
  • 2005 Dec;4(2):101-106.
PURPOSE: Photodynamic therapy was used to lung cancer. We have made a light microscpic study on the effects of photodynamic therapy to tumor graft in skin of mice, when the...
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Herpes Simplex virus thymidine kinase gene therapy delivered by retroviral or adenoviral vector in mouse model of lewis lung carcinoma

Kwon HC, Jeong JM, Kim JH, Ham YH, Seo JS, Chang KH, Kim M, Lee HS, Lee CT

BACKGROUND: The antitumor effects of herpes simplex virus thymidine kinase(HSV-tk) and ganciclovir(GCV) strategies for cancer gene therapy have a the following advantages:1) a direct cytotoxicity to HSV-tk modified cancer cells...
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Inoculation of Lewis lung carcinoma cells enhances formalin-induced pain behavior and spinal Fos expression in mice

Choi JG, Kim JM, Kang DW, Choi JW, Park JB, Ahn SH, Ryu Y, Kim HW

The incidence of lung cancer has rapidly increased and cancer patients at a later cancer stage frequently suffer from unbearable cancer-associated pain. However, the pathophysiology of lung cancer pain has...
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Inhibition of Lewis Lung Carcinoma Growth by Toxoplasma gondii through Induction of Th1 Immune Responses and Inhibition of Angiogenesis

Kim JO, Jung SS, Kim SY, Kim TY, Shin DW, Lee JH, Lee YH

Toxoplasma gondii is an obligate intracellular protozoan parasite that induces antitumor activity against certain types of cancers. However, little information is available regarding the immunologic mechanisms that regulate these effects....
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Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity

Hu J, Chen LJ, Liu L, Chen X, Chen PL, Yang G, Hou WL, Tang MH, Zhang F, Wang XH, Zhao X, Wei YQ

Honokiol is an active compound purified from magnolia that has been shown to induce cell differentiation, apoptosis, and anti-angiogenesis effects, as well as an enhancement in tumor growth delay in...
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Dendritic Cell (DC) Vaccine in Mouse Lung Cancer Minimal Residual Model; Comparison of Monocyte-derived DC vs. Hematopoietic Stem Cell Derived-DC

Baek S, Lee SJ, Kim MJ, Lee H

The anti-tumor effect of monocyte-derived DC (MoDC) vaccine was studied in lung cancer model with feasible but weak Ag-specific immune response and incomplete blocking of tumor growth. To overcome this...
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Combination Gene Therapy of Herpes Simplex Virus Thymidine Kinase and Cytokines in Lung Cancer

Kim G, Park KH, Seol JY, Yoo CG, Lee CT, Kim YW, Han SK, Shim YS

BACKGROUND: One of the important mechanisms responsible for a tumor escaping the immune response is an absence of the tumor associated antigen (TAA) on the cancer cell surface. To overcome...
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Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells

Park HW, Song JY, Kim KS, Han Y, Kim CW, Yi SY, Yun YS

  • KMID: 1123762
  • Exp Mol Med.
  • 2004 Oct;36(5):411-419.
Ceramide generated from sphingomyelin in response to ionizing radiation has been implicated as a second messenger to induce cellular proapoptotic signals. Both ceramide and its metabolic inhibitor, N, N-dimethyl-D-erythro-sphingosine (DMS),...
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Immunogenic Cell Death Induced by Ginsenoside Rg3: Significance in Dendritic Cell-based Anti-tumor Immunotherapy

Son KJ, Choi KR, Lee SJ, Lee H

Cancer is one of the leading causes of morbidity and mortality worldwide; therefore there is a need to discover new therapeutic modules with improved efficacy and safety. Immune-(cell) therapy is...
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Cyclooxygenase-2 (COX-2) Inhibitors Reduce Immune Tolerance through Indoleamine 2,3-dioxygenase (IDO)

Lee SY, Lee KJ, Jung JY, Lee EJ, Kang EH, Jung KH, Lee SY, Kim JH, Shin C, Shim JJ, In KH, Kang KH, Yoo SH

PURPOSE : Cyclooxygenase-2 (COX-2) and its metabolite, PGE2 affect multiple tumorigenesis, including angiogenesis, invasion, and tumor-induced immune suppression. Their overexpression is association with impaired immune cell function in many tumors....
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