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Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells

Lampiasi N, Azzolina A, Montalto G, Cervello M

  • KMID: 1047079
  • Exp Mol Med.
  • 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on...
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Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib

Kang D, Han Z, Oh GH, Joo Y, Choi HJ, Song JJ

PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism...
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