- Thalidomide Accelerates the Degradation of Extracellular Matrix in Rat Hepatic Cirrhosis via Down-Regulation of Transforming Growth Factor-beta1
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Lv P, Meng Q, Liu J, Wang C
- KMID: 2345885
- Yonsei Med J.
- 2015 Nov;56(6):1572-1581.
- doi: 10.3349/ymj.2015.56.6.1572
PURPOSE: The degradation of the extracellular matrix has been shown to play an important role in the treatment of hepatic cirrhosis. In this study, the effect of thalidomide on the... -
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- Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/beta-Catenin Signaling Pathway
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Li W, Zhu C, Li Y, Wu Q, Gao R
- KMID: 1774562
- Gut Liver.
- 2014 May;8(3):282-291.
BACKGROUND/AIMS: The Wnt/beta-catenin signaling pathway has been reported to play an important role in liver fibrosis. This study was designed to investigate whether mesoderm-specific transcript homologue (Mest), a strong negative... -
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- Elk-3 Contributes to the Progression of Liver Fibrosis by Regulating the Epithelial-Mesenchymal Transition
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Li TZ, Kim SM, Hur W, Choi JE, Kim JH, Hong SW, Lee EB, Lee JH, Yoon SK
- KMID: 2412161
- Gut Liver.
- 2017 Jan;11(1):102-111.
- doi: 10.5009/gnl15566
BACKGROUND/AIMS: The role of Elk-3 in the epithelial-mesenchymal transition (EMT) during liver fibrogenesis remains unclear. Here, we determined the expression of Elk-3 in in vitro and in vivo models and... -
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- Histochemical and Ultrastructural Studies of Hepatic Fibrogenesis; Its Initiation and the Effect of Dexamethasone in Rats
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Kim CJ, Park CI, Kim CS, Lee YB
- KMID: 692940
- Yonsei Med J.
- 1982 Dec;23(2):89-100.
- doi: 10.3349/ymj.1982.23.2.89
Intralobular fibrogenesis of the liver following hepatocellular damage has long been a controversial subject in regard to its initiation and prevention. To investigate the site of hepatic fibrogenesis and the... -
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