- Mechanism of an increase in concentration of intracellular calcium by carbachol in human gastric smooth muscle cell
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Moon W, Kim YH, Park DI, Rhee PL, Kim JJ, Koh KC, Rhee JC, Choi KW, Kang TM
- KMID: 2306142
- Korean J Med.
- 2001 May;60(5):432-438.
BACKGROUND: The contraction of smooth muscle depends on an increase in the concentration of intracellular calcium ion and the source of this increase to various stimuli is different according to... -
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- The Effects of Heparin and Protamine on Contraction of Tracheal Smooth Muscle Induced by Carbachol in the Guinea Pig
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Kwon OK, Kang SH
- KMID: 2238382
- Korean J Anesthesiol.
- 2005 Feb;48(2):177-181.
- doi: 10.4097/kjae.2005.48.2.177
BACKGROUND: Several reports have indicated that heparin has a bronchodilative effect in asthma patients, and that it enhances airway smooth muscle contraction in vitro, protamine is known to inhibit... -
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- Effects of intracameral carbachol and acetylcholine on early postoperative intraocular pressure after cataract extraction
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Kim JY, Sohn JH, Youn DH
- KMID: 1735125
- Korean J Ophthalmol.
- 1994 Dec;8(2):61-65.
- doi: 10.3341/kjo.1994.8.2.61
We performed a randomized, prospective study to evaluate the effect of intraoperative, intracameral carbachol or acetylcholine on early postoperative intraocular pressure(IOP) after extracapsular cataract extraction(ECCE) and posterior chamber lens(PCL) implantation.... -
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- Effects of Ketamine on Carbachol and Epidermal Growth Factor Contraction in Rat Trachea
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Kim JE, Woo NS, Cho SI
- KMID: 2031565
- Korean J Anesthesiol.
- 2000 Aug;39(2):219-225.
- doi: 10.4097/kjae.2000.39.2.219
BACKGROUND: It is well known that ketamine, a dissociative anesthetic, inhibits smooth muscle contractions induced by high KCl and receptor agonists such as carbachol, histamine and endothelin. It has been... -
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- The Effects of Diazepam on the Carbachol Induced Contraction of the Isolated Rat Ileum
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Kim JO, Kwon OC, Ha JH, Lee KY, Kim WJ
- KMID: 2377226
- Yeungnam Univ J Med.
- 1989 Dec;6(2):13-22.
- doi: 10.12701/yujm.1989.6.2.13
To investigate the effect of diazepam on the contractility of the intestinal smooth muscle, longitudinal muscle strip isolated from rat ileum was prepared for myography in isolated organ bath. 1) Basal... -
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- Muscarinic receptor subtype controlling the carbachol-induced muscle contraction in guinea pig gastric antrum
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Rhee JC, Uhm DY, Kang TM
- KMID: 1982596
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):105-111.
Stimulation of muscarinic receptors by carbachol (CCh) in the circular smooth muscle of the guinea pig gastric antrum causes muscle contraction. In the present study, muscarinic receptor subtype controlling the muscle contraction in... -
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- Unilateral Frontal Hyperhidrosis
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Choi GJ, Oh YJ, Kim HO, Kim CW
- KMID: 1678630
- Korean J Dermatol.
- 1982 Dec;20(6):919-923.
Unilaterl frontal hyperhidrosis, a rare disorder of the sweat gland with localized hyperhidrosis, ia discribed. A 13-year-old female patient had increased sweating on the left half of the forehead, recurring... -
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- The Pharmacological and Histological Comparison Between Detubularized and Tubularized Cystoplasty Ileum in the Rat
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Jung SY, Lee HB, Yoon JY, Chun CS
- KMID: 2060700
- Korean J Urol.
- 1997 Mar;38(3):235-240.
Bowel segments are used either in a tubular or detubular configuration in bladder augmentation and substitutions. The majority of urologists agree that detubularized segments give better clinical results,but detailed studies... -
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- Drug Interactions of Intrathecal Carbachol and Clonidine in Neuropathic Pain Model of the Rats
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Lee EJ, Lee YS, Hwang JH, Han SM
- KMID: 2039878
- Korean J Anesthesiol.
- 1998 Apr;34(4):716-724.
- doi: 10.4097/kjae.1998.34.4.716
BACKGROUND: After peripheral nerve injury in human, a syndrome of events (spontaneous pain, allodynia and hyperalgesia) may be observed that includes no response of morphine and dependency of this pain... -
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- Inhibitory Effects of Potassium Channel Blockers on Carbachol-induced Contraction in Rat Detrusor Muscle
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Oh SJ, Ahn SC
- KMID: 1130042
- J Korean Med Sci.
- 2003 Oct;18(5):701-706.
- doi: 10.3346/jkms.2003.18.5.701
We present accidental findings that potassium channel blockers, such as tetraethyl-ammonium (TEA) or 4-aminopyridine (4-AP), inhibit the sustained tonic contraction induced by carbachol in rat detrusor muscle strips. The relatively... -
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- Primary role of posterior hypothalamic cholinergic receptors in central regulation of blood pressure and heart rate in rats
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Kim SY, Sung KW, Koh HC, Lee SB
- KMID: 2285181
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):639-645.
The purpose of the present study is to determine the role of muscarinic cholinergic receptors of posterior hypothalamus in the central blood pressure regulation when respiration is controlled. In anesthetized and artificially ventilated... -
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- The Role of Intracellular Ca2+ in Inhibiting Somatostatin-Induced Pancreatic Amylase Release
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Rhie DJ, Kim HW, Song IY, Yi SY, Yoon SH, Hahn SJ, Sim SS, Kim MS, Jo YH
- KMID: 2304684
- Korean J Gastroenterol.
- 1998 Dec;32(6):782-791.
BACKGROUND/AIMS: We previously found that somotostatin (SS) inhibited amylase release partly by inhibiting basal cellular cAMP formation in pancreatic acini. In the present study, we verified the effect of SS... -
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- Local Effects of Antimuscarinics on Muscarinic Receptors in Bladder Sensory Nerves
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Park MS, Cho SW, Han KH, Lee SC, Kim WJ, Kim YT
- KMID: 2330522
- J Korean Continence Soc.
- 2006 Jun;10(1):17-22.
PURPOSE: To investigate the role of muscarinic receptors in bladder sensory mechanism. MATERIALS AND METHODS: Normal adult volunteers collected voided urine after taking five days of trospium(20 mg bid), tolterodine LA(4... -
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- Organophosphate Cholinesterase Inhibitor (Diisopropylfluorophosphate) Induces Acetylcholinesterase-mediated Nicotinic Receptor Facilitation
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Sung JJ, Park KS, Lee KW
- KMID: 2342859
- J Korean Neurol Assoc.
- 2000 Nov;18(6):735-740.
BACKGROUND: Cholinesterase inhibitors (ChEIs) which have been widely used clinically are known to have diverse actions on the neuromuscular synaptic transmissions, suggesting that inhibiting cholinesterase (ChE) might not be their... -
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- The Role of the Central Parasympathetic Nervous System in Modulating Glucose Metabolism in Streptozotocin-induced Diabetic Rats
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Lee KE, Pae YS
- KMID: 1964933
- Ewha Med J.
- 1995 Jun;18(2):97-103.
- doi: 10.12771/emj.1995.18.2.97
Insulin controls the levels of blood sugar by inhibiting glucose release from liver and by stimulating glucose utilization in muscle and adipose tissues. In addition to its peripheral effects, insulin... -
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- Inhibitory effect of caffeine on carbachol-induced nonselective cationic current in guinea-pig gastric myocytes
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Kim SJ, Min KW, Kim YC, Lee SJ, So I, Kim KW
- KMID: 1849843
- Korean J Physiol Pharmacol.
- 1998 Jun;2(3):353-359.
In gastrointestinal smooth muscle, muscarinic stimulation by carbachol (CCh) activates nonselective cation channel current (ICCh) which is facilitated by intracellular (Ca2+) increase. Caffeine is widely used in experiments to mobilize Ca2+ from intracellular... -
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- Stimulation of Cl- secretion by AlF4- and vanadate in T84 cells
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Hwang TH, Jung JS, Bae HR, Yun I, Lee SH
- KMID: 644842
- J Korean Med Sci.
- 1994 Dec;9(6):497-504.
- doi: 10.3346/jkms.1994.9.6.497
We investigated the mechanism of Cl- secretion by fluoroaluminate(AlF4-) and sodium orthovanadate(vanadate) using the human colonic T84 cell line. T84 cell monolayers grown on collagen-coated filters were mounted in Ussing... -
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- Evaluation of Colonic Physiologic Properties in Old Rats using in vitro and in vivo Techniques
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Kim SE, Jung SA
- KMID: 2171135
- Ewha Med J.
- 2004 Mar;27(1):3-9.
- doi: 10.12771/emj.2004.27.1.3
OBJECTIVES: As the lifespan of men have been extended, the interest in functional aging process of each organs is increasing. The aim of this study was to investigate lbjectively several... -
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- Epithelial Modulation on Guinea-pig Tracheal Smooth Muscle Tension to Contractile Agents
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Koo BN, Koh SO, Kim WO, Kim KJ, Nam YT, Seo MS, Kim SJ
- KMID: 1936308
- Korean J Anesthesiol.
- 2000 May;38(5):920-926.
- doi: 10.4097/kjae.2000.38.5.920
BACKGROUND: Asthma can be described as the hypersensitivity of the airway to various stimuli. Injury to tracheal epithelial cells could be the reason for tracheal hypersensitivity in asthma or... -
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- Enhanced coupling of M-1 muscarinic receptors to activation of phospholipase C upon mutation of a transposed amino acid triplet repeat
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Lee SY, Sung KW, Kim ON, Lee SB
- KMID: 2285154
- Korean J Physiol Pharmacol.
- 1997 Feb;1(1):19-25.
The C-terminus ends of the second putative transmembrane domains of both M-1 and M-2 Muscarinic receptors contain a triplet of amino acid residues consisting of leucine (L), tyrosine (Y) and threonine (T). This... -
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