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Identifying Trends in Oncology Research through a Bibliographic Analysis of Cancer Research and Treatment

Lee Ck, Choo JM, Ahn YC, Kim J, Rha SY, Rim CH, On behalf of the 50th Anniversary Committee of the Korean Cancer Association

During the celebration of the 50th anniversary of the founding of the Korean Cancer Association, articles published in Cancer Research and Treatment from 2004 to 2023 were assessed based on...
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The Cancer Clinical Library Database (CCLD) from the Korea-Clinical Data Utilization Network for Research Excellence (K-CURE) Project

Lee S, Choi YH, Kim HM, Hong MA, Park P, Kwak IH, Kang YJ, Choi KS, Kong HJ, Cha H, Kim HJ, Ryu KS, Jeon YS, Kim H, Jung JM, Im JS, Chae H

The common data model (CDM) has found widespread application in healthcare studies, but its utilization in cancer research has been limited. This article describes the development and implementation strategy for...
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Trends in Cancer-Screening Rates in Korea: Findings from the National Cancer Screening Survey, 2004-2023

Kang E, Choi KS, Jun JK, Kim Y, Lee HJ, Choi CK, Kim TH, Lee SH, Suh M

Purpose This study aimed to report the overall national trends in the rates of cancer screening based on recommendations and provide insights into the changing trends of these rates across...
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Factors Associated with Postoperative Recurrence in Stage I to IIIA Non–Small Cell Lung Cancer with Epidermal Growth Factor Receptor Mutation: Analysis of Korean National Population Data

Kim KY, Kim HC, Kim TJ, Kim HK, Moon MH, Beck KS, Suh YG, Song CH, Ahn JS, Lee JE, Jeon JH, Jung CY, Cho JS, Choi YD, Hwang SS, Choi CM, Jang SH, Lim JU, Korean Association for Lung Cancer, Korea Central Cancer Registry

Purpose Recent development in perioperative treatment of resectable non–small cell lung cancer (NSCLC) have changed the landscape of early lung cancer management. The ADAURA trial has demonstrated the efficacy of...
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Grit and the Relationships among Psychological Distress and Suicidality in Female Patients with Breast Cancer

You JS, Park CHK

Purpose The risk of suicide is approximately two times higher in patients with breast cancer compared to the general population. Suicide risk factors are widely investigated but research on the...
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Association of TP53 Mutation Status and Sex with Clinical Outcome in Non–Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors: A Retrospective Cohort Study

Choi S, Kim SH, Lee S, Seo J, Kang M, Jung EH, Kim SA, Suh KJ, Lee JY, Kim JW, Kim JW, Lee JO, Kim YJ, Lee KW, Kim JH, Bang SM, Lee JS

Purpose Some studies suggest that TP53 mutations are associated with the response to immune checkpoint inhibitors (ICI) in patients with non–small cell lung cancer (NSCLC) and also contribute to sex...
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The Oncogenic Role of TNFRSF12A in Colorectal Cancer and Pan-Cancer Bioinformatics Analysis

Wang C, Zhao Y, Chen Y, Shi Y, Yang Z, Wu W, Ma R, Wang B, Sun Y, Yuan P

Purpose Cancer has become a significant major public health concern, making the discovery of new cancer markers or therapeutic targets exceptionally important. Elevated expression of tumor necrosis factor receptor superfamily...
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Salvage Radiotherapy for Loco-regional Recurrence of Esophageal Cancer Following Surgery

Cho WK, Noh JM, Oh D, Ahn YC, Sun JM, Kim HK, Shim YM

Purpose There is few evidence regarding the optimal salvage treatment options for loco-reginal recurrence of esophageal cancer. This study aimed to evaluate the clinical outcomes of salvage radiotherapy (RT) in...
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Molecular Classification of Breast Cancer Using Weakly Supervised Learning

Jang W, Lee J, Park KH, Kim A, Lee SH, Ahn S

Purpose The molecular classification of breast cancer is crucial for effective treatment. The emergence of digital pathology has ushered in a new era in which weakly supervised learning leveraging whole-slide...
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Proximal Gastrectomy Is Associated with Lower Incidence of Anemia and Vitamin B12 Deficiency Compared to Total Gastrectomy in Patients with Upper Gastric Cancer

Song JH, Park SH, Cho M, Kim YM, Hyung WJ, Kim HI

Purpose Proximal gastrectomy is an alternative to total gastrectomy (TG) for early gastric cancer (EGC) treatment in the upper stomach. However, its benefits in terms of perioperative and long-term outcomes...
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Endoxifen Concentration Is Associated with Recurrence-Free Survival in Hormone-Sensitive Breast Cancer Patients

Lee B, Nam SJ, Kim SW, Yu J, Chae BJ, Lee SK, Ryu JM, Lee JE, Lee SY

Purpose The metabolism of tamoxifen is influenced by various cytochrome p450 enzymes, including CYP2D6 and CYP2C19, leading to variations in the levels of endoxifen, even with the same tamoxifen dose....
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A Single-Arm Phase II Clinical Trial of Fulvestrant Combined with Neoadjuvant Chemotherapy of ER+/HER2– Locally Advanced Breast Cancer: Integrated Analysis of 18F-FES PET-CT and Metabolites with Treatment Response

Shao Q, Zhang N, Pan X, Zhou W, Wang Y, Chen X, Wu J, Zeng X

Purpose This Phase II trial was objected to evaluate the efficacy and safety of adding fulvestrant to neoadjuvant chemotherapy in patients with estrogen receptor (ER)+/human epidermal growth factor receptor 2...
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The Survival and Financial Benefit of Investigator-Initiated Trials Conducted by Korean Cancer Study Group

Kim BJ, Maeng CH, Keam B, Im YH, Ro J, Jung KH, Im SA, Kim TW, Lee JL, Heo DS, Kim SW, Park K, Ahn MJ, Cho BC, Kim HK, Kang YK, Cho JY, Yun HJ, Nam BH, Zang DY

Purpose The Korean Cancer Study Group (KCSG) is a nationwide cancer clinical trial group dedicated to advancing investigator-initiated trials (IITs) by conducting and supporting clinical trials. This study aims to...
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Upfront Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy in Elderly Patients with Brain Metastases from Non–Small Cell Lung Cancer: A Retrospective Analysis of a 10-Year Bi-institutional Experience

Kim M, Cha J, Kim HJ, Kim WC, Lee J

Purpose Stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) are increasingly used as initial therapies for brain metastases (BM). We aimed to assess the outcomes of SRS/FSRT in patients aged...
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Integrating Deep Learning–Based Dose Distribution Prediction with Bayesian Networks for Decision Support in Radiotherapy for Upper Gastrointestinal Cancer

Kim DY, Jang BS, Kim E, Chie EK

Purpose Selecting the better techniques to harbor optimal motion management, either a stereotactic linear accelerator delivery using TrueBeam (TBX) or magnetic resonance–guided gated delivery using MRIdian (MRG), is time-consuming and...
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Fecal Microbial Dysbiosis Is Associated with Colorectal Cancer Risk in a Korean Population

Kim J, Gunathilake M, Yeo HY, Oh JH, Kim BC, Han N, Kim B, Pyun H, Lim MY, Nam YD, Chang HJ

Purpose The association between the fecal microbiota and colorectal cancer (CRC) risk has been suggested in epidemiologic studies. However, data from large-scale population-based studies are lacking. Materials and Methods In this...
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Recurrence Dynamics of Pathological N2 Non–Small Cell Lung Cancer Based on IASLC Residual Tumor Descriptor

Kim IH, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Yun JK

Purpose This study investigated the recurrence patterns and timing in patients with pathologic N2 (pN2) non-small cell lung cancer (NSCLC) according to the residual tumor (R) descriptor proposed by the International...
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Assessing the Efficacy of Bortezomib and Dexamethasone for Induction and Maintenance Therapy in Relapsed/Refractory Cutaneous T-Cell Lymphoma: A Phase II CISL1701/BIC Study

Choi YS, Shim J, Kang KW, Yoon SE, Hong JS, Lim SN, Yhim HY, Kwon JH, Lee GW, Yang DH, Oh SY, Shin HJ, Eom HS, Yoon DH, Lee HG, Jeong SH, Kim WS, Kim SJ

Purpose This multicenter, open-label, phase II trial evaluated the efficacy and safety of bortezomib combined with dexamethasone for the treatment of relapsed/refractory cutaneous T-cell lymphoma (CTCL) in previously treated patients...
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Differences in the Prognostic Impact between Single-Zone and Multi-Zone N2 Node Metastasis in Patients with Station-Based Multiple N2 Non–Small Cell Lung Cancer

Kim S, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Yun JK

Purpose The International Association for the Study of Lung Cancer suggests further subdivision of pathologic N (pN) category in non–small-cell lung cancer (NSCLC) by incorporating the location and number of...
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Enhancing Identification of High-Risk cN0 Lung Adenocarcinoma Patients Using MRI-Based Radiomic Features

Kim H, Kim J, Hwang S, Oh YJ, Ahn JH, Kim MJ, Hong TH, Park SG, Choi JY, Kim HK, Kim J, Shin S, Lee HY

Purpose This study aimed to develop a magnetic resonance imaging (MRI)–based radiomics model to predict high-risk pathologic features for lung adenocarcinoma: micropapillary and solid pattern (MPsol), spread through air space,...
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