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Effect of Chlorella intake on Cadmium metabolism in rats

Shim JA, Son YA, Park JM, Kim MK

  • KMID: 2313372
  • Nutr Res Pract.
  • 2009 Mar;3(1):15-22.
This study was performed to investigate the effect of chlorella on cadmium (Cd) toxicity in Cd- administered rats. Sixty male Sprague-Dawley rats (14 week-old) were blocked into 6 groups. Cadmium...
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Changes of Tight Junction and Epithelial Cells after Treatment of Cadmium

Lee SJ, Kim KY, Kim DJ, Chung YH, Kim SS, Lee WB, Cho DY, Sohn DS

  • KMID: 1512957
  • Korean J Phys Anthropol.
  • 2007 Mar;20(1):69-82.
Cadmium (Cd) affects cell proliferation, differentiation, apoptosis and other cellular activities and can cause numerous molecular lesions that would be relevant to carcinogenesis. The mechanism of adverse effects of Cd...
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Evidence for Cyclooxygenase-2 Association with Caveolin-3 in Primary Cultured Rat Chondrocytes

Kwak JO, Lee WK, Kim HW, Jung SM, Oh KJ, Jung SY, Huh YH, Cha SH

The purpose of this study was to demonstrate the cellular localization of cyclooxygenase-2 (COX-2) and caveolin-3 (Cav-3) in primarily cultured rat chondrocytes. In normal rat chondrocytes, we observed relatively high...
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Effect of Thiopental on Transient Outward Current (Ito) and Inwardly Rectifying K+ Current (Ik1) in Rat Ventricular Myocytes

Kim MH, Yoon KB, Lee KM, Lee WJ, Park WK

BACKGROUND: Patients with the long QT syndrome, either congenital or acquired, have an increased development of serious ventricular arrhythmia, Torsade de Pointes. Thiopental (5 mg/kg) has been reported to prolong...
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Heterogeneity of the SR-dependent Inward Na+-Ca2+ Exchange Current in the Heavily Ca2+-buffered Rat Ventricular Myocytes

Yoon KB, Ahn SW, Ko CM

  • KMID: 1611236
  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):101-110.
Voltage-sensitive release mechanism was pharmacologically dissected from the Ca2+-induced Ca2+ release in the SR Ca2+ release in the rat ventricular myocytes patch-clamped in a whole-cell mode. SR Ca2+ release process...
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Renal Tubular Acidosis in Cadmium-Intoxicated Rats

Ahn DW, Kim KR, Choi JK, Park YS

  • KMID: 1614859
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):41-46.
Effect of cadmium (Cd) intoxication on renal acid-base regulation was studied in adult male Sprague-Dawley rats. Cd intoxication was induced by subcutaneous injections of CdCl2 at a dose of 2...
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Changes of Superoxide Dismutase Activity in Cadmium-induced Acute Nephrotoxicity of Rats

Lee SJ, Koh HC, Park CY

  • KMID: 2028164
  • Korean J Occup Environ Med.
  • 2001 Dec;13(4):393-400.
OBJECTIVES: To investigate the role of superoxide dismutase(SOD) in the pathogenesis of cadmium-induced acute nephrotoxicity. METHODS: Rats treated with a single intraperitoneal injection of cadmium(as CdCl2, 1 mg/kg) were included in...
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Forward-mode Na+ - Ca2+ exchange during depolarization in the rat ventricular myocytes with high EGTA

Kim EG, Ko CM

  • KMID: 1607137
  • Korean J Physiol Pharmacol.
  • 2001 Dec;5(6):487-494.
During depolarization, extrusion of Ca2+ from sarcoplasmic reticulum through forward-mode Na+ - Ca2+ exchange was studied in the rat ventricular myocytes patch-clamped in whole-cell configuration. In order to confine the...
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Relationship between Malondialdehyde in Renal Cortex and Urinary NAG Activity of Rats exposed to Cadmium

Lee SJ, Koh HC, Moon CJ, Park CY

  • KMID: 2144221
  • Korean J Aerosp Environ Med.
  • 2001 Sep;11(3):165-171.
BACKGROUND: To investigate the relationship between malondialdehyde in renal cortex and Urinary NAG activity of rats exposed to cadmium. METHODS: Rats were treated with a single intraperitoneal injection of cadmium...
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Separate and Combined Effect of Cadmium and Nickel on Blood Pressure in Rats

Wang SJ, Cha BS

  • KMID: 1982658
  • Korean J Prev Med.
  • 2001 May;34(2):127-130.
OBJECTIVE: To verify the separate and combined effects of cadmium and nickel on blood pressure in rats. METHODS: Following the daily administration of cadmium chloride(CdCl2) and nickel chloride(NiCl2) to rats both...
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A Study on the Congenital Anomalies induced by Cadmium Chloride

Kim EJ, Kim S, Yang EJ, Han SR, Kim SI, Kim WS

  • KMID: 2071862
  • Korean J Phys Anthropol.
  • 2000 Jun;13(2):239-251.
The purpose of this study is to observe the optimium effects of cadmium chloride on the rat fetus. Cadmium chloride 5 mg/kg was administered intraperitoneally once to the pregnant rats...
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Neurotensin enhances gastric motility in antral circular muscle strip of guinea-pig.

Koh TY, Kim SJ, Lee SJ, Kang TM, Yeoul JJ, Sim JH, So I, Kim KW

  • KMID: 1580809
  • Korean J Physiol Pharmacol.
  • 2000 Jun;4(3):227-234.
Many reports suggest that neurotensin (NT) in the gastrointestinal tract may play a possible role as a neurotransmitter, a circulating hormone, or a modulator of motor activity. NT exerts various actions in the...
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Comparative Hepatotoxicity Assessment of Cadmium and Nickel with Isolated Perfused Rat Liver(IPRL)

Cha BS, Wang SJ, Chang SJ, Lee JW

  • KMID: 2283092
  • Korean J Prev Med.
  • 2000 Mar;33(1):117-124.
OBJECTIVES: It is the objective of this study to compare hepatotoxicity of nickel chloride and cadmium chloride with each other through IPRL(Isolated Perfused Rat Liver) method. METHODS: Biochemical indicator of hepatic...
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Hepatic Effect of Simultaneous Exposure to Nickel and Cadmium in Rats

Cha BS, Wang S, Chang SJ

  • KMID: 2028090
  • Korean J Occup Environ Med.
  • 2000 Mar;12(1):111-118.
OBJECTIVES: This research was intended to verify hepatic effect of simutaneously combined exposure of nickel chloride and cadmium chloride with IPRL(Isolated Perfused Rat Liver) method. METHODS: AST(aspartate aminotransferase), ALT(alanine aminotransferase),...
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Histological and Biochemical Study on the Effect of Cadmium Chloride on the Rat Testis

Kim WS, Myung PK, Yang EJ, Cho KJ

  • KMID: 2092712
  • Korean J Anat.
  • 2000 Feb;33(1):29-40.
Although cadmium is a well known heavy metal which has an influence testis and brings about male infertility, the mechanism of action in the testis is still fully unknown. In...
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Changes in phosphate transporter activity evaluated by phosphonoformic acid binding in cadmium-exposed renal brush-border membranes

Chung JM, Ahn DW, Kim KR, Park YS

  • KMID: 2071553
  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):513-519.
Direct exposure of renal tubular brush-border membranes (BBM) to free cadmium (Cd) causes a reduction in phosphate (Pi) transport capacity. Biochemical mechanism of this reduction was investigated in the present study. Renal proximal...
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Effect of Cadmium and Zinc on IL-6 Secretion in a Human Monocytic Cell Line, THP-1

Shin DH, Suh SK, Suh SI

  • KMID: 1532053
  • Korean J Occup Environ Med.
  • 1999 Sep;11(3):332-339.
OBJECTIVES: This study was performed to investigate effects of cadmium and zinc on IL-6 secretion using human monocyte in a culture system. METHODS: We have used frypan blue dye exclusion...
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A Study on the Protective Effects of Glutathione on Cytotoxicity of Mercury and Cadmium

Jeong JH, Kim JY, Koh DH

  • KMID: 2282994
  • Korean J Prev Med.
  • 1999 Jun;32(2):170-176.
OBJECTIVES: To evaluate the protective effects of glutathione (GSH) on the cytotoxicity of mercurial compounds(CH3HgCl, HgCl2) or cadmium chloride(CdCl2) in EMT-6 cells. METHODS: The compounds investigated were CH3HgCl, HgCl2, CdCl2, GSH,...
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Effects of Chelators on Liver Cadmium Contents in Chronic Cadmium Intoxication Rats

Lee SH, Lee KT, Lee JH, Lee JK, Rhee PL, Kim JJ, Koh KC, Paik SW, Rhee JC, Choi KW

  • KMID: 2241335
  • Korean J Hepatol.
  • 1998 Mar;4(1):59-68.
BACKGROUND/AIMS: The heavy metals like cadmium (Cd) are neither destroyed nor produced in human body and may infiltrated into air, water, soil, food, human body and redistributed by biological and geographical circulation....
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Effect of Antioxidant on the Toxicity Induced by Cadmium in Preimplantatio Embryos In Vitro

Hong GY, Lee BJ, Rhee HS, Kim HG, Min BK, Kim KS, Park ST

  • KMID: 1924376
  • Korean J Obstet Gynecol.
  • 1997 May;40(5):935-940.
In order to elucidate the mechanism of oxidative damage of cadimu(Cd) on culturedmouse preimplantation embyors.The embryotoxocity of Cd was examined after cultured mouse preimplantation embryoswere exposed to various concentrations of...
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