- Characterization of cytoplasmic Form of Human CTLA - 4 Molecule
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Cho YJ, Chung YH, Han HS
- KMID: 1548223
- Korean J Immunol.
- 1997 Jun;19(2):219-228.
CTLA-4 (=CD152), a T cell activation antigen, has been known to be homologous to CD28 in its molecular and genomic structure. Both of these two molecules are sharing their counterreceptors,... -
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- CTLA-4 Polymorphism in Myasthenia Gravis
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Park JH, Lee CH, Lee JS, Kim HS, Kim WJ, Lee KY, Choi YC
- KMID: 2137943
- J Korean Neurol Assoc.
- 2004 Oct;22(5):504-507.
BACKGROUND: Cytotoxic T lymphocyte associated antigen 4 (CTLA-4) plays a role in down-regulating both the cellular and the humoral responses by suppressing the ongoing responses of activated T-cells. There are... -
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- Characterization of CTLA-4 Antigen Expression Identification of Molecules Composing Intracellular CTLA-4 Multiprotein Complex
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Rhim DC, Chung YH
- KMID: 1571390
- Immune Netw.
- 2002 Mar;2(1):35-40.
- doi: 10.4110/in.2002.2.1.35
BACKGROUND: CTLA-4 (Cytotoxic T Lymphocyte associated Antigen 4, CD152) has been known as a homologue of CD28, an accessory molecule providing a key costimulatory signal for successful antigen-driven activations of... -
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- Phenotypic Characteristics of PD-1 and CTLA-4 Expression in Symptomatic Acute Hepatitis A
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Cho H, Kang H, Kim CW, Kim HY, Jang JW, Yoon SK, Lee CD
- KMID: 2363975
- Gut Liver.
- 2016 Mar;10(2):288-294.
- doi: 10.5009/gnl14368
BACKGROUND/AIMS: The immunoregulatory molecules programmed death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) are associated with the dysfunction of antiviral effector T-cells, which leads to T-cell exhaustion and... -
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- Cancer Immunotherapy Related Endocrine Adverse Effects
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Kim H, Cho SW, Park YJ
- KMID: 2465062
- Int J Thyroidol.
- 2019 Nov;12(2):97-104.
- doi: 10.11106/ijt.2019.12.2.97
Cancer immunotherapy has emerged as a promising therapy for a wide variety of tumors. Immune checkpoint inhibitors including anti cytotoxic T lymphocyte antigen 4 (CTLA-4), programmed death 1 (PD-1) and... -
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- Immune-related Adverse Events: Overview and Management Strategies for the Use of Immune Checkpoint Inhibitors
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Jeung HC, Oh SE, Kim JH
- KMID: 2459447
- J Rheum Dis.
- 2019 Oct;26(4):221-234.
- doi: 10.4078/jrd.2019.26.4.221
Recent studies on T cell immunology have been instrumental in developing therapies to overcome cancer immune escape, and immune checkpoint inhibitors have emerged as one of the most promising therapeutic... -
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- Update on immune checkpoint inhibitors in gynecological cancers
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Heong V, Ngoi N, Tan DS
- KMID: 2413459
- J Gynecol Oncol.
- 2017 Mar;28(2):e20.
- doi: 10.3802/jgo.2017.28.e20
In recent years, progress in our understanding of immune-modulatory signaling pathways in immune cells and the tumor microenvironment (TME) has led to rejuvenated interest in cancer immunotherapy. In particular, immunotherapy... -
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- Immunotherapy for Non-small-cell Lung Cancer: Current Status and Future Obstacles
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Cho JH
- KMID: 2400624
- Immune Netw.
- 2017 Dec;17(6):378-391.
- doi: 10.4110/in.2017.17.6.378
Lung cancer is one of the leading causes of death worldwide. There are 2 major subtypes of lung cancer, non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC). Studies show... -
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- Immune-Checkpoint Inhibitors in the Era of Precision Medicine: What Radiologists Should Know
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Braschi-Amirfarzan M, Tirumani S, Hodi FS, Nishino M
- KMID: 2468121
- Korean J Radiol.
- 2017 Feb;18(1):42-53.
- doi: 10.3348/kjr.2017.18.1.42
Over the past five years immune-checkpoint inhibitors have dramatically changed the therapeutic landscape of advanced solid and hematologic malignancies. The currently approved immune-checkpoint inhibitors include antibodies to cytotoxic T-lymphocyte antigen-4,... -
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- Clinical Update in Aspects of the Management of Autoimmune Thyroid Diseases
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Topliss DJ
- KMID: 2373066
- Endocrinol Metab.
- 2016 Dec;31(4):493-499.
- doi: 10.3803/EnM.2016.31.4.493
Aspects of autoimmune thyroid disease updated in this review include: immunoglobulin G4 (IgG4)-related thyroid disease (Riedel's thyroiditis, fibrosing variant of Hashimoto's thyroiditis, IgG4-related Hashimoto's thyroiditis, and Graves' disease with elevated... -
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- Diagnostic value of peripheral blood immune profiling in colorectal cancer
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Choi J, Maeng HG, Lee SJ, Kim YJ, Kim DW, Lee HN, Namgung JH, Oh HM, Kim TJ, Jeong JE, Park SJ, Choi YM, Kang YW, Yoon SG, Lee JK
- KMID: 2412401
- Ann Surg Treat Res.
- 2018 Jun;94(6):312-321.
- doi: 10.4174/astr.2018.94.6.312
PURPOSE: Little is known about the clinical value of peripheral blood immune profiling. Here, we aimed to identify colorectal cancer (CRC)-related peripheral blood immune cells and develop liquid biopsy-based immune... -
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