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Proinflammatory Effects of High Mobility Group B1 (HMGB1) Versus LPS and the Mechanism of IL-8 Promoter Stimulation by HMGB1

Jeon EJ, Kwak HW, Song JH, Lee YW, Chung JW, Choi JC, Shin JW, Park IW, Choi BW, Kim JY

BACKGROUND: High mobility group box 1 (HMGB1) is a novel, late mediator of inflammation. This study compared the pro-inflammatory effects of LPS and HMGB1. The transcriptional factors that play an...
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