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The role of the gut microbiome and diet in the pathogenesis of non-alcoholic fatty liver disease

Jennison E, Byrne CD

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease, with a prevalence that is increasing in parallel with the global rise in obesity and type 2...
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Noninvasive serum biomarkers for liver fibrosis in NAFLD: current and future

Reinson T, Buchanan RM, Byrne CD

In the last 20 years, noninvasive serum biomarkers to identify liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) have been developed, validated against liver biopsy (the gold standard...
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Lifestyle Interventions for Non-Obese Patients Both with, and at Risk, of Non-Alcoholic Fatty Liver Disease

Zhang XL, Wang TY, Targher G, Byrne CD, Zheng MH

Non-alcoholic fatty liver disease occurring in non-obese subjects (the so-called non-obese NAFLD) is a highly prevalent but neglected liver condition, which is closely associated with metabolic disorders and suboptimal lifestyles....
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Old and new classes of glucose-lowering agents as treatments for non-alcoholic fatty liver disease: A narrative review

Miao L, Xu J, Targher G, Byrne CD, Zheng MH

Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease with a global prevalence of about 55% in people with type 2 diabetes mellitus (T2DM). T2DM, obesity...
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