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Regulation of fibronectin gene expression by cyclic AMP and phorbol myristate acetate in HT-1080 human fibrosarcoma cells

Lee BH, Park RW, Kim IS

  • KMID: 755015
  • Exp Mol Med.
  • 1998 Dec;30(4):240-245.
We studied the regulation of fibronectin (FN) gene expression by cAMP and phorbol-12-myristate-13-acetate (PMA) in HT-1080 human fibrosarcoma cells. Dibutyryl cAMP increased FN synthesis and mRNA levels, while PMA inhibited...
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Phosphorylation of phospholipase D1 and the modulation of its interaction with RhoA by cAMP-dependent protein kinase

Jang MJ, Lee MJ, Park HY, Bae YS, Min DS, Ryu SH, Kwak JY

  • KMID: 1380212
  • Exp Mol Med.
  • 2004 Apr;36(2):172-178.
Agents that elevate cellular cAMP are known to inhibit the activation of phospholipase D (PLD). We investigated whether PLD can be phosphorylated by cAMP-dependent protein kinase (PKA) and PKA-mediated phosphorylation...
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Human SNF2L Gene Is Regulated Constitutively and Inducibly in Neural Cells via a cAMP-Response Element

Xia Y, Wang L, Ma C, Gong Y, Zhao Y

PURPOSE: SNF2L belongs to Imitation Switch family and plays an essential role in neural tissues and gonads. In our previous studies, we have demonstrated that the basal transcription of human...
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Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins

Shah BH

  • KMID: 1029937
  • Exp Mol Med.
  • 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells...
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CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells

Lee EJ, Lee HG, Park SH, Choi EY, Park SH

  • KMID: 1093617
  • Exp Mol Med.
  • 2003 Oct;35(5):438-447.
CD99 is a 32-kDa cell surface molecule present on thymocytes, peripheral T cells, many other hematopoietic stem cells and somatic cells were implicated in cell-cell adhesion and cell-activation phenomena. Two...
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