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IL-4 and IL-5 Secretions Predominate in the Airways of Wistar Rats Exposed to Toluene Diisocyanate Vapor

Kouadio K, Zheng KC, Toure AA, Dosso M, Todoriki H

  • KMID: 1791969
  • J Prev Med Public Health.
  • 2014 Jan;47(1):57-63.
OBJECTIVES: We established a Wistar rat model of asthma caused by toluene diisocyanate (TDI) exposure, and investigated the relationship between TDI exposure concentrations and respiratory hypersensitivity, airway inflammation, and cytokine...
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Alveolar macrophages modulate allergic inflammation in a murine model of asthma

Bang BR, Chun E, Shim EJ, Lee HS, Lee SY, Cho SH, Min KU, Kim YY, Park HW

The role of alveolar macrophages (AMs) in the pathogenesis of asthma is still unknown. The aim of the present study was to investigate the effects of AM in the murine...
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Are pulmonary hemostasis and fibrinolysis out of balance in equine chronic pneumopathies?

Barton AK, Wirth C, Bondzio A, Einspanier R, Gehlen H

Clinical examination, bronchoalveolar lavage fluid (BALF) cytology, acute-phase protein, and pulmonary hemostasis and fibrinolysis marker (fibrinogen, serum amyloid A [SAA], and D-dimer) results were compared between control and respiratory disease-affected...
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Proteomic differences with and without ozone-exposure in a smoking-induced emphysema lung model

Uh ST, Koo SM, Jang AS, Park SW, Choi JS, Kim YH, Park CS

BACKGROUND/AIMS: Acute exacerbations in chronic obstructive pulmonary disease may be related to air pollution, of which ozone is an important constituent. In this study, we investigated the protein profiles associated...
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An antioxidant modulates expression of receptor activator of NF-kappaB in asthma

Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L, Lee YC

  • KMID: 1094147
  • Exp Mol Med.
  • 2006 Jun;38(3):217-229.
Oxidative stress plays critical roles in airway inflammation that is usually accompanied by increased vascular permeability and plasma exudation. VEGF increases vascular permeability and leads to airway inflammation. In addition,...
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