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High Activities of Protein Kinases C and M in Fresh Human Stomach and Breast Tumors

Lim IK, Lee DJ, Lee KH, Yun TK

The activities of Ca+2-PL dependent protein Kinase (PKC) and independent protein kinase(RKM) were measured in human stomach and breast tumors and in the respective counterparts of normal tissue. Expression of...
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Alternative splicing in 5'-untranslational region of STK-15 gene, encoding centrosome associated kinase, in breast cancer cell lines

Shin SO, Lee KH, Kim JH, Baek SH, Park JW, Gabrielson EW, Kwon TK

  • KMID: 755098
  • Exp Mol Med.
  • 2000 Dec;32(4):193-196.
Centrosomes maintain genomic stability by establishing the bipolar spindles during cell division and, execute accurate segregation of chromosomes during mitosis. In this study, we have demonstrated that there...
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A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-beta1-induced MMP-1 and MMP-9 expression in breast cancer cells

Kim S, Han J, Shin I, Kil WH, Lee JE, Nam SJ

  • KMID: 1387358
  • Exp Mol Med.
  • 2012 Aug;44(8):473-482.
Overexpression of HER2 correlates with more aggressive tumors and increased resistance to cancer chemotherapy. However, a functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on tumor metastasis has not...
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Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women

Lee SA, Kang D, Nishio H, Lee MJ, Kim DH, Han W, Yoo KY, Ahn SH, Choe KJ, Hirvonen A, Noh DY

  • KMID: 1380205
  • Exp Mol Med.
  • 2004 Apr;36(2):116-121.
To evaluate the interactive effect of methylenetetrahydrofolate reductase (MTHFR) genotype and dietary factors on the development of breast cancer, a hospital based case-control study was conducted in South Korean study...
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Genetic polymorphism of CYP17 and breast cancer risk in Korean women

Shin MH, Lee KM, Yang JH, Nam SJ, Kim JW, Yoo KY, Park SK, Noh DY, Ahn SH, Kim B, Kang D

  • KMID: 1033096
  • Exp Mol Med.
  • 2005 Feb;37(1):11-17.
CYP17 gene is involved in steroidogenesis and steroid metabolism. Epidemiologic results on the association between the CYP17 polymorphism and breast cancer risk have been inconsistent. We examined the association between...
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