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Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas

Mandrioli , Panarese S, Cesari A, Mandara MT, Marcato PS, Bettini G

Telomere length maintenance is regarded as a fundamental step in tumorigenesis, as most human brain tumors, including meningiomas, stabilize the ends of their chromosomes using telomerase. This investigation represents an...
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Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression

Hur JH, Park MJ, Park IC, Yi DH, Rhee CH, Hong SI, Lee SH

To evaluate possible roles of matrix metalloproteinase (MMP)-1, -2, tissue inhibitor of metalloproteinase (TIMP)-1, -2 and membrane-type-1 matrix metalloproteinase (MT1-MMP) in invasion of human gliomas, expressions of these proteins were...
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Prognostic Implication of Telomerase Activity in Patients with Brain Tumors

Kim CH, Cheong JH, Bak KH, Kim JM, Oh SJ

Telomerase adds telomeric repeats to the ends of telomeres to compensate for their progressive loss. A favorable prognosis is associated with low or no telomerase in some tumors. The authors...
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