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5-Fluorouracil-induced leukoencephalopathy in patients with breast cancer

Choi SM, Lee SH, Yang YS, Kim BC, Kim MK, Cho KH

The purpose of this study is to determine the characteristic clinical features, radiologic findings, and precipitating and prognostic factors in the patients with breast cancer and with 5-Fluorouracil (5-FU)-induced leukoencephalopathy....
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Cerebral energy metabolism following ESWL brain injury model and effects of cerebral protective drugs

Whang CJ, Kwon Y

The goal of this study was to introduce a new method inducing an experimental brain injury model using ESWL(Extracorporeal Shock Wave Lithotripsy) and to evaluate findings of localized lesions on...
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Effects of alpha-Phenyl-N-tert-Butyl Nitrone (PBN)on Brain Cell Membrane Function and Energy Metabolism during Transient Global Cerebral Hypoxia-Ischemia and Reoxygenation-Reperfusion in Newborn Piglets

Choi CW, Hwang JH, Chang YS, Shin SM, Park WS, Lee M

We sought to know whether a free radical spin trap agent, alpha-phenyl-N-tert-butyl nitrone (PBN) influences brain cell membrane function and energy metabolism during and after transient global hypoxia-ischemia (HI) in...
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Brain MRI Findings of Carbon Disulfide Poisoning

Cha JH, Kim SS, Han H, Kim RH, Yim SH, Kim MJ

OBJECTIVE: To evaluate the findings of brain MRI in patients with carbon disulfide poisoning. MATERIALS AND METHODS: Ninety-one patients who had suffered carbon disulfide poisoning [male:female=87:4; age, 32-74 (mean 53.3) years]...
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Establishment of minimal positive-control conditions to ensure brain safety during rapid development of emergency vaccines

Baek H, Kim KH, Park MY, Kim K, Ko B, Seo HS, Kim BS, Hahn TW, Yi SS

With the increase in international human and material exchanges, contagious and infectious epidemics are occurring. One of the effective methods of epidemic inhibition is the rapid development and supply of...
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Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata

Lee KH, Huh JW, Choi MM, Yoon SY, Yang SJ, Hong HN, Cho SW

  • KMID: 1093472
  • Exp Mol Med.
  • 2005 Aug;37(4):371-377.
When treated with protopine and alkalized extracts of the tuber of Corydalis ternata for one year, significant decrease in glutamate level and increase in glutamate dehydrogenase (GDH) activity was observed...
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Regional differences in the levels of biogenic amines and their metabolites in rat brain after tricyclic antidepressant treatments

Chung MY, Kim DG, Yoo KJ, Hong SS

Changes in the levels of biogenic amines in different brain regions and the cerebrospinal fluid in rats were measured after acute or chronic treatment with tricyclic antidepressants. After single or...
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Differences in Regional Glucose Metabolism of the Brain Measured with F-18-FDG-PET in Patients with Essential Tremor According to Their Response to Beta-Blockers

Song IU, Ha SW, Yang YS, Chung YA

OBJECTIVE: In this study, there was an investigation as to whether there is a functional difference in essential tremor (ET), according to responses to beta-blockers, by evaluating regional changes in...
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