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Genistein-Induced Apoptosis of p815 Mastocytoma Cell

Song KH, Song KH, Kim KH

BACKGROUND: Numerous studies demonstrated that genistein induced the decrease of proliferation and apoptosis in a variety of cells. However, there is no report about the effect of genistein on proliferation...
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Mitochondrial Permeability Transition Pore and Cardioprotection Against Ischemia-reperfusion Injury

Lee JW, Shim YH

Opening of mitochondrial permeability transition pore (mPTP) was found to have a critical role in cell death from ischemia/reperfusion (I/R) injury experimentally in the late 1980's. Thereafter, tremendous efforts have...
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Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction

Chae YJ, Kim HS, Rhim HS, Kim BE, Jeong SW, Kim IK

  • KMID: 1457543
  • Exp Mol Med.
  • 2001 Dec;33(4):284-292.
3-Deazaadenosine (DZA), a cellular methylation blocker was reported to induce the caspase-3-like activities-dependent apoptosis in U-937 cells. In this study, we analyzed the activation pathway of the caspase cascade involved...
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