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Response of Human Renal Cell Carcinoma Cells to Bone Morphogenetic Proteins, and the Expression of Bone Morphogenetic Protein Receptors

Lee DH, Chung JH, Kim IY

  • KMID: 2293755
  • Korean J Urol.
  • 2003 Feb;44(2):160-167.
PURPOSE: Bone morphogenetic protein (BMP) is a pleiotropic growth factor, which has been suggested to play a critical role during the development and homeostasis of the kidney. We evaluated the...
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Genetics in heritable pulmonary arterial hypertension

Lee YJ

  • KMID: 2259198
  • Korean J Med.
  • 2010 Jan;78(1):20-27.
Pulmonary arterial hypertension is caused by vascular remodeling including muscularization of arteries, loss of small precapillary arteries, and formation of neointima and plexiform lesion, resulting in a progressive increase in...
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Changes in the Expression of Bone Morphogenetic Protein Receptor Type IA, IB and II in Human Prostate by the Suppression of Dihydrotestosterone

Kwon SM, Kim SI, Lee JR, Lee DH, Hong SJ

  • KMID: 2292522
  • Korean J Urol.
  • 2002 Dec;43(12):1045-1050.
PURPOSE: To investigate whether the expression of type IA, IB and II bone morphogenetic protein receptors (hBMPRs) are affected by the suppression of dihydrotestosterone (DHT) in the prostate tissues of...
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Bone Morphogenetic Protein Receptor in the Osteogenic Differentiation of Rat Bone Marrow Stromal Cells

Wang A, Ding X, Sheng S, Yao Z

PURPOSE: Several signaling pathways have been shown to regulate the lineage commitment and terminal differentiation of bone marrow stromal cells (BMSCs). Bone morphogenetic protein (BMP) signaling has important effects on...
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15 years journey of idiopathic pulmonary arterial hypertension with BMPR2 mutation

Ahn KJ, Jang AY, Park SJ, Chung WJ

Pulmonary arterial hypertension (PAH) is known as one of diseases with the worst prognosis. Recently, targeted PAH drugs have been developed and approved for use; therefore, the treatment strategy and...
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Field Cancerization in Sporadic Colon Cancer

Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4...
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